You searched for : 'U'

NOZINAN® Rhône-Poulenc Rorer Methotrimeprazine Neuroleptic Action And Clinical Pharmacology: Methotrimeprazine possesses antipsychotic, tranquilizing, anxiolytic, sedative and analgesic properties and it is also a potent potentiator of anesthetics. Methotrimeprazine possesses strong sedative properties. It potentiates ether and hexobarbital anesthesia as well as morphine analgesia. It also exerts a potent anti-apomorphine effect, a hypothermic action 3 times more potent than that of chlorpromazine and strong antispasmodic and anti-histaminic effects. Methotrimeprazine is capable…

NOVO-VALPROIC Novopharm Valproic Acid Anticonvulsant Action And Clinical Pharmacology: Although not yet established, the mechanism of valproic acid’s anticonvulsant activity may be related to increased brain concentrations of gamma-aminobutyric acid (GABA). The effect of the drug on the neuronal membrane is unknown. Valproic acid is rapidly absorbed after oral administration, with peak serum levels occurring approximately 1 to 4 hours after a single oral dose. The half-life of valproic acid…

NOVO-VERAMIL SR Novopharm Verapamil HCl Antiarrhythmic – Antianginal – Antihypertensive Antihypertensive Action And Clinical Pharmacology: Angina and Arrhythmia: Verapamil, a calcium ion influx inhibitor (calcium entry blocker or calcium ion antagonist) is believed to exert its antiarrhythmic and antianginal effects by selectively inhibiting transmembrane influx of calcium ions in cardiac muscle, coronary and systemic arteries and in cells of the intracardiac conduction system. Verapamil blocks the transmembrane influx of calcium…

NOVOCAIN® Sanofi Procaine HCl Local Anesthetic Action And Clinical Pharmacology: Local anesthetics block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the action potential. In general, the progression of anesthesia is related to the diameter, myelination, and conduction velocity of affected nerve fibres….

NOVAMOXIN® Novopharm Amoxicillin Trihydrate Antibiotic Action And Clinical Pharmacology: Amoxicillin exerts its bactericidal action by interfering with bacterial cell wall synthesis. Indications And Clinical Uses: The treatment of infections due to susceptible strains of the following microorganisms: Gram-negative organisms: H. influenzae, P. mirabilis and N. gonorrhea. Gram-positive organisms: streptococci (including S. faecalis and S. pneumoniae). Amoxicillin is not active against P. aeruginosa, indole-positive Proteus species, S. marcescens, Klebsiella and Enterobacter…

NOVAHISTEX® C Hoechst Marion Roussel Codeine Phosphate – Phenylephrine HCl Antitussive – Decongestant Indications And Clinical Uses: The treatment of adults with cough associated with inflamed mucosa, which does not respond to products of lesser potency. Dosage: Adults: 5 mL every 4 to 6 hours. Children: 6 to 12 years, one-half adult dosage; not recommended for children under 6 years. Availability And Storage: Each 5 mL of red, raspberry flavored…

NOVANTRONE® Wyeth-Ayerst Mitoxantrone HCl Antineoplastic Action And Clinical Pharmacology: Although its mechanism of action has not been determined, mitoxantrone is a DNA-reactive agent. It induces nuclear aberrations with chromosome scattering in cell cultures (human colon carcinoma line) and is a potent inhibitor of RNA and DNA synthesis. Compared on an equimolar basis, mitoxantrone is 7 times more potent than doxorubicin in inhibiting the uptake of -uridine and 4 times more…

NOVAHISTEX® DM NOVAHISTEX® DM Decongestant NOVAHISTEX® DM Decongestant Expectorant NOVAHISTINE® DM NOVAHISTINE® DM Decongestant NOVAHISTINE® DM Decongestant Expectorant Hoechst Marion Roussel Dextromethorphan HBr Dextromethorphan HBr – Pseudoephedrine HCl Dextromethorphan HBr – Pseudoephedrine HCl – Guaifenesin Dextromethorphan HBr Dextromethorphan HBr – Pseudoephedrine HCl Dextromethorphan HBr – Pseudoephedrine HCl – Guaifenesin Antitussive Antitussive – Decongestant Antitussive – Decongestant – Expectorant Antitussive Antitussive – Decongestant Antitussive – Decongestant – Expectorant Action And Clinical…

NOVAHISTEX® DH EXPECTORANT Hoechst Marion Roussel Hydrocodone Bitartrate – Guaifenesin – Phenylephrine HCl Antitussive – Expectorant – Decongestant Indications And Clinical Uses: In adults, to facilitate expectoration and control cough associated with inflamed mucosa and tenacious sputum which does not respond to products of lesser potency. Contraindications, Precautions, Adverse Effects  Guaifenesin has been shown to produce a color interference with certain clinical laboratory determinations of 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic…

NOVAHISTEX® DH Hoechst Marion Roussel Hydrocodone Bitartrate – Phenylephrine HCl Antitussive – Decongestant Indications And Clinical Uses: The treatment of adults with cough associated with inflamed mucosa, which does not respond to products of lesser potency. Contra-Indications: Patients undergoing therapy with MAO inhibitors, hypersensitivity to any of the components. Precautions: Before prescribing medication to suppress or modify cough, it is important to ascertain that the underlying cause of the cough…