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RESONIUM CALCIUM Sanofi Calcium Polystyrene Sulfonate Ion Exchange Resin Action And Clinical Pharmacology: Calcium polystyrene sulfonate is a cation exchange resin prepared in the calcium phase. Each gram of resin has a theoretical in vitro exchange capacity of about 1.3 to 2 mmol of potassium. In vivo, the actual amount of potassium bound will be less than this. The sodium content of the resin is less than 1 mg/g. The…

REQUIP™ SmithKline Beecham Ropinirole HCl Antiparkinsonian Agent – Dopamine Agonist Action And Clinical Pharmacology: Ropinirole is a non-ergoline dopamine agonist, which activates postsynaptic dopamine receptors. In vitro studies have shown that ropinirole binds with high affinity to cloned human D2, D3, and D4 receptors. The antiparkinson activity of ropinirole is believed to be due to its stimulatory effects on central postsynaptic dopamine D2 receptors within the caudate-putamen. Ropinirole is a…

RESOURCE® DIABETIC Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: A high nitrogen, fibre containing complete liquid formula. Designed for persons with Type 1 or Type 2 diabetes or stress hyperglycemia and normal gastrointestinal function. For oral or tube feeding use. Not recommended when a low residue tube feeding is required. Precautions: Not for parenteral administration. Dosage And Administration: 1 250 mL or 5 550 kJ (5 cans or 1…

RESOURCE® FRUIT BEVERAGE Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: For patients requiring oral supplementation. For the dietary management of increased protein and calorie needs in the following patient groups: oncology, anorexia, pre-and post-operative, bowel preparation and fat malabsorption. Follow physician’s instructions for use. Precautions: Not for parenteral administration. Dosage: 8 Tetra Paks [1 880 mL or 6 020 kJ (1 440 kcal)] provides 1 440 kcal and at…

RENOVA® Janssen-Ortho Tretinoin Agent for the Treatment of Photodamaged Skin Action And Clinical Pharmacology: Tretinoin significantly reduces clinical signs of photodamaged skin such as fine wrinkles, mottled hyperpigmentation and roughness. While the exact mechanism of action of tretinoin is unknown, the clinical improvements are accompanied by the following histologic changes: increased epidermal and granular layer thickness, reduced melanin content and stratum corneum alterations. Indications And Clinical Uses: For the treatment…

RENEDIL® Hoechst Marion Roussel Felodipine Antihypertensive Agent Action And Clinical Pharmacology: Felodipine is a calcium ion influx inhibitor (calcium channel blocker). Felodipine is a member of the dihydropyridine class of calcium channel blockers. Mechanism of Action: The therapeutic effect of this group of drugs is believed to be related to their specific cellular action of selectively inhibiting transmembrane influx of calcium ions into cardiac muscle and vascular smooth muscle. The…

REOPRO™ Lilly Abciximab Chimeric Monoclonal Antiplatelet Antibody Action And Clinical Pharmacology: General: Abciximab is the Fab fragment of the chimeric monoclonal antibody 7E3. It selectively binds to the glycoprotein IIb/IIIa (GPIIb/IIIa) receptor located on the surface of human platelets. Abciximab inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor and other adhesive molecules to GPIIb/IIIa receptor sites on activated platelets. Pharmacokinetics: Following i.v. administration of abciximab, free…

REPLENS® Roberts Polycarbophil Vaginal Moisturizer – Lubricant Action And Clinical Pharmacology: Polycarbophil, the key ingredient, is a bioadhesive polymer which can carry up to 60 times its weight in water. It adheres to the epithelial cells lining the vaginal walls and delivers electrolytes and water. The polymer is detached only upon the shedding of the outer layer of cells or mucin, a normal healthy process which occurs every 2 or…

RECOMBIVAX HB® MSD Hepatitis B Vaccine (Recombinant) Vaccine Action And Clinical Pharmacology: Hepatitis B virus is one of at least 3 hepatitis viruses that cause a systemic infection, with major pathology in the liver. The others are hepatitis A virus, and non-A, non-B hepatitis viruses. Hepatitis B virus is an important cause of viral hepatitis. There is no specific treatment for this disease. The incubation period for type B hepatitis…

REDOXON® Roche Ascorbic Acid Vitamin Indications And Clinical Uses: Prevention and treatment of deficiency of ascorbic acid. Ascorbic acid is essential for the formation of collagen and intercellular material, and hence for the development of cartilage, bone and teeth, and for wound healing. It influences the formation of hemoglobin, erythrocyte maturation, and certain immunological reactions in the body. The reducing properties of ascorbic acid are useful in the treatment of…