Replens (Polycarbophil)




Vaginal Moisturizer – Lubricant

Action And Clinical Pharmacology: Polycarbophil, the key ingredient, is a bioadhesive polymer which can carry up to 60 times its weight in water. It adheres to the epithelial cells lining the vaginal walls and delivers electrolytes and water. The polymer is detached only upon the shedding of the outer layer of cells or mucin, a normal healthy process which occurs every 2 or 3 days. The polycarbophil is negatively charged and this causes the water and electrolytes to be driven into the underlying cells. Electrolytes are also driven into the vasculature causing vasodilation, which results in (i) an increase in blood supply to the tissue and (ii) a greater transudation of fluids which pass into and through the tissues. The electrolytes and water moisturize and lubricate the vaginal tissue and thus relieve the discomfort caused by vaginal dryness. The increased blood flow can lead to enhanced secretion as vaginal fluids diffuse from blood.

In addition, the polymer, polycarbophil, has a low pH of 2.8 and has the ability to keep the pH of the vagina stable. It maintains vaginal pH in the physiologically normal range (4.5 to 5.5, or fairly acid) thereby making it less susceptible to bacterial infection.

Indications: Relieves vaginal dryness, itching and painful intercourse for up to 3 days with a single application.

Warnings: Keep out of the reach of children. Replens is not a contraceptive. Does not contain spermicide or hormones.

Dosage: Use as needed. One application every 2 to 3 days is recommended.

Availability And Storage: Each single-use disposable applicator delivers 2.5 g. Nonstaining, fragrance-free, paraben-free, unflavored and nongreasy. Nonmedicinal ingredients: carbomer 934P, glycerin, hydrogenated palm oil glyceride, mineral oil, polycarbophil, purified water and sorbic acid. Individually-wrapped prefilled applicators, boxes of 3 and 8.

REPLENS® Roberts Polycarbophil Vaginal Moisturizer – Lubricant

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