APO®-CEFACLOR Apotex Cefaclor Antibiotic Action And Clinical Pharmacology: Like other b-lactam antibiotics, cefaclor owes its antibacterial activity to its ability to bind to and inhibit the action of certain bacterial cell wall synthetic enzymes, the penicillin-binding proteins. Cefaclor is well absorbed after oral administration to fed and fasted subjects. Following doses of 250 mg, 500 mg, and 1 g to fasted subjects, average peak serum levels of approximately 7, 13…
You searched for : 'E'
Apo1 (Cefaclor)
(Pharmaceutical)Antibiotic Cold Sore Oinment (Polymyxin B)
(Pharmaceutical)ANTIBIOTIC COLD SORE OINTMENT Novartis Consumer Health Polymyxin B Compound Cold Sore Therapy Indications And Clinical Uses: Symptomatic treatment of cold sores and fever blisters. Prevention of secondary bacterial infection. Contra-Indications: Hypersensitivity to any of the components. Manufacturers’ Warnings In Clinical States: It is dangerous to apply any product containing menthol or camphor to the nostrils of an infant. To do so may cause difficulty in breathing and collapse. Precautions:…
Antiphlogistine Rub A (Methyl Salicylate)
(Pharmaceutical)ANTIPHLOGISTINE RUB A-535 Carter Horner Methyl Salicylate – Camphor – Menthol – Eucalyptus Oil Topical Analgesic Indications And Clinical Uses: External counterirritant cream for temporary pain relief of stiff and sore muscles, backache, strains, arthritic and rheumatic pain, sciatica, lumbago and bursitis. Contra-Indications: Salicylate hypersensitivity. Precautions: For external use only. Do not apply to wounds or damaged skin and avoid contact with eyes and mucous membranes. Discontinue use if…
Antivenom
(Pharmaceutical)Antivenin (Latrodectus Mactans) MSD Black Widow Spider Antivenin Indications And Clinical Uses: Used to treat patients suffering from symptoms due to bites from the black widow spider. Early use of the antivenin is emphasized for prompt relief. Manufacturers’ Warnings In Clinical States: Prior to treatment with any product prepared from horse serum, a careful review of the patient’s history should be taken emphasizing prior exposure to horse serum or any…
Antivert (Meclizine)
(Pharmaceutical)ANTIVERT Pfizer Meclizine HCl – Nicotinic Acid Vertigo Therapy Action And Clinical Pharmacology: Meclizine has antihistaminic and anticholinergic properties. Nicotinic acid is a vasodilator agent which has been found effective in the treatment of vertigo due to cerebral arteriosclerosis. The site and mechanism of action of meclizine in controlling vertigo arising from various conditions, have not been clearly defined. Pharmacological studies conducted with other antihistamines show that the peripheral labyrinthine…
Anturan (Sulfinpyrazone)
(Pharmaceutical)ANTURAN® Novartis Pharmaceuticals Sulfinpyrazone Platelet Inhibitory Agent – Uricosuric Agent – Prophylactic Agent for Reduction of Mortality Post-myocardial Infarction Action And Clinical Pharmacology: Sulfinpyrazone inhibits thrombotic processes that are associated with platelet adhesion, aggregation and reduced platelet survival. Sulfinpyrazone reduces serum urate levels, prevents formation of new tophi, and promotes resorption of existing tophi by increasing clearance of uric acid and water through the kidneys. Sulfinpyrazone has been shown to…
Ansaid (Flurbiprofen)
(Pharmaceutical)ANSAID® Pharmacia & Upjohn Flurbiprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Flurbiprofen, a phenylalkanoic acid derivative, is a nonsteroidal anti-inflammatory agent which also possesses analgesic and antipyretic activities. Its mode of action, like that of other nonsteroidal anti-inflammatory agents, is not known. However, its therapeutic action is not due to pituitary-adrenal stimulation. Flurbiprofen is an inhibitor of prostaglandin synthesis. The resulting decrease in prostaglandin synthesis may partially explain the…
Antabuse (Disulfiram)
(Pharmaceutical)ANTABUSE® Wyeth-Ayerst Disulfiram Alcohol Deterrent Action And Clinical Pharmacology: Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage. During alcohol metabolism after disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of…
Androcur (Cyproterone Acetate)
(Pharmaceutical)ANDROCUR® ANDROCUR® DEPOT Berlex Canada Cyproterone Acetate Antiandrogen Action And Clinical Pharmacology: Cyproterone is a steroid which clinically demonstrates 2 distinct properties: Antiandrogenic: Cyproterone blocks the binding of dihydrotestosterone – the active metabolite of testosterone – to the specific receptors in the prostatic carcinoma cell. Progestogenic/antigonadotrophic: Cyproterone exerts a negative feed-back on the hypothalamo-pituitary axis, by inhibiting the secretion of LH leading to diminished production of testicular testosterone. The absorption…
Andriol (Testosterone Undecanoate)
(Pharmaceutical)ANDRIOL Organon Testosterone Undecanoate Androgen Action And Clinical Pharmacology: Testosterone undecanoate, an orally active testosterone preparation, is a fatty acid ester of the natural androgen testosterone. Unlike other oral testosterone preparations, testosterone undecanoate is able to by-pass the liver via the lymphatic system and is therefore orally bioavailable. Therapy with Andriol increases plasma levels of testosterone and its active metabolites, leading to a regular therapeutic effect. In eugonadal men, peak…