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URISPAS® Pharmascience Flavoxate HCl Urinary Tract Antispasmodic Action And Clinical Pharmacology: Flavoxate is a papaverine-like smooth muscle relaxant. It exhibits, however, greater antispasmodic activity and is less toxic. The basic action of flavoxate is the relaxation of smooth muscle fibres of the urinary tract through a mechanism not yet defined. By counteracting smooth muscle spasms of the urinary tract, it relieves the pain and discomfort accompanying a variety of urological…

UROMITEXAN™ Bristol Mesna Uroprotector Action And Clinical Pharmacology: Mesna is rapidly and easily converted by autooxidation to its only metabolite disodium 2,2¢-dithio-bis ethane sulfonate (mesna disulfide, dimesna), forming a disulfide link. Following i.v. injection, only a small portion of the administered dose is detected in the blood as a reactive thiol compound (mesna). Mesna disulfide remains in the intravascular space and is rapidly forwarded to the kidney. In the renal…

URASAL® Carter Horner Hexamine Urinary Antiseptic Indications And Clinical Uses: Mild and chronic urinary tract infections, especially cystitis, prostatitis, urethritis. Symptoms And Treatment Of Overdose: Symptoms: Nausea, anorexia, pain on urination. Treatment: Gastric lavage or emesis. In children, induce emesis and if there is no immediate response, use gastric lavage. No known antidote. Dosage: 2 level teaspoonfuls in 240 mL of water 3 times a day before meals, or as…

UNIVOL® Carter Horner Magnesium Hydroxide – Aluminum Hydroxide Antacid Indications And Clinical Uses: For the symptomatic relief of hyperacidity associated with peptic ulcer, gastritis, esophagitis, heartburn or hiatal hernia. Contra-Indications: Not to be given to patients who are severely debilitated or suffering from renal failure. Alkalosis, hypermagnesemia. Manufacturers’ Warnings In Clinical States: Do not take more than 80 mL during a 24-hour period. Do not take the maximum dosage for…

TRASICOR® Novartis Pharmaceuticals Oxprenolol HCl Antihypertensive Action and Clinical Uses: Oxprenolol is a noncardioselective beta-adrenergic receptor blocking agent which possesses partial agonist activity. It is used in the treatment of hypertension.: The mechanism of the antihypertensive effect has not been established. Among the factors which may be involved are: a) competitive ability to antagonize catecholamine induced tachycardia at the beta-receptor sites in the heart, thus decreasing cardiac output; b) inhibition…

TRANXENE® Abbott Clorazepate Dipotassium Anxiolytic-Sedative Availability And Storage: Each capsule contains: clorazepate dipotassium 3.75 mg (grey with white cap), 7.5 mg (grey with maroon cap) or 15 mg (grey with grey cap). Also contains: cellulose microcrystalline, magnesium stearate, potassium carbonate, potassium chloride and talcum powder. Alcohol-, gluten-, lactose-, paraben-, sodium-, sucrose-, sulfite- and tartrazine-free. Bottles of 100. TRANXENE® Abbott Clorazepate Dipotassium Anxiolytic-Sedative

TOPICORT® Preparations Hoechst Marion Roussel Desoximetasone Topical Corticosteroid Action and Clinical Topicort preparations are primarily effective because of their anti-inflammatory, antipruritic and vasoconstrictive actions. Indications And Clinical Uses: For the relief of acute or chronic corticosteroid-responsive dermatoses. Contra-Indications: Topical corticosteroids are contraindicated in untreated bacterial, tubercular, fungal and most viral lesions of the skin (including herpes simplex, vaccinia and varicella) and in those patients with a history of hypersensitivity to…

TOLEREX® Novartis Nutrition Elemental Diet Indications And Clinical Uses: A nutritionally complete elemental diet formulated for the nutritional management of patients with impaired digestion and absorption. May include those with inflammatory bowel disease, intestinal atresia, pancreatitis, fistula, partial obstruction, short-gut syndrome. Malnutrition and cachexia. Bowel preparation prior to diagnostic and surgical procedures. Transition diet between parenteral and normal oral feeding. Food sensitivities.: Precautions: Not for parenteral administration. For use only…

TOBREX® Alcon Tobramycin Topical Antibiotic Action and Clinical Like other aminoglycosides, the bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria, but at the present time, very little is known about this action. It is thought that inhibition of synthesis is due to an action on ribosomes that, in turn, causes bacterial misreading of messenger RNA. Because the ocular concentrations of tobramycin achieved…

TOBRADEX® Alcon Tobramycin-Dexamethasone Antibiotic-Corticosteroid Action and Clinical Uses: Dexamethasone, a potent corticosteroid, suppresses the inflammatory response to chemical, immunological or mechanical irritants. The bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria. Indications And Clinical Uses: For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exist. Ocular steroids are indicated…