You searched for : 'X'

FLAXEDIL® Rh´ne-Poulenc Rorer Gallamine Triethiodide Muscle Relaxant Action And Clinical Pharmacology: Gallamine is a competitive neuromuscular blocking agent. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Following usual i.v. doses muscle relaxation occurs rapidly and reaches a…

FERTINORM® HP Serono Urofollitropin Gonadotropin Action And Clinical Pharmacology: Fertinorm HP is a highly purified preparation of the gonadotropin, Follicle Stimulating Hormone (FSH) extracted from the urine of postmenopausal women. The principal action of Fertinorm HP is the induction of follicular growth in infertile women who do not have primary ovarian failure. Treatment in most instances results only in follicular growth and maturation. In order to effect ovulation in the…

FEXICAM Technilab Piroxicam Nonsteroidal Anti-inflammatory – Analgesic – Antipyretic Action And Clinical Pharmacology: Piroxicam is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action is incompletely known. Piroxicam inhibits the activity of prostaglandin synthetase. Its anti-inflammatory action may be partially explained by the resulting decrease in prostaglandin biosynthesis. Its therapeutic action is not due to pituitary-adrenal stimulation. In rheumatoid arthritis the efficacy of piroxicam 20 mg…

FELDENE™ Pfizer Piroxicam Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Piroxicam is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action is incompletely known. Piroxicam inhibits the activity of prostaglandin synthetase. The resulting decrease in prostaglandin biosynthesis may partially explain its anti-inflammatory action. Piroxicam does not act by pituitary-adrenal stimulation. In rheumatoid arthritis the efficacy of piroxicam 20 mg daily has been found to be similar…

FANSIDAR® Roche Sulfadoxine – Pyrimethamine Antimalarial Action And Clinical Pharmacology: Fansidar is a combination of sulfadoxine and pyrimethamine, which inhibits sequential steps involved in the biosynthesis of tetrahydrofolic acid. This depletes folic acid, an essential cofactor in the biosynthesis of nucleic acids, resulting in interference with protozoal nucleic acid and protein production. Sulfadoxine is a structural analogue of para-aminobenzoic acid (PABA) and competitively inhibits the enzyme dihydropteroate synthetase. Pyrimethamine is…

FEIBA® VH IMMUNO Baxter Human Plasma Factor VIII Inhibitor Coagulant Complex Anti-inhibitor Description: Feiba VH Immuno, is a freeze-dried sterile human plasma fraction with Factor VIII inhibitor bypassing activity. In vitro, Feiba VH Immuno shortens the activated partial thromboplastin time (APTT) of plasma containing Factor VIII inhibitor. Factor VIII inhibitor bypassing activity is expressed in arbitrary units. One Immuno Unit of activity is defined as that amount of Feiba VH…

EX-LAX® Chocolated Pieces EX-LAX® Sugar Coated Pills EX-LAX® Extra Strength Sugar Coated Pills Novartis Consumer Health Sennosides Laxative Action And Clinical Pharmacology: Sennosides are a natural source complex of anthraquinone glycosides found in senna. They exert a stimulant laxative effect that increases peristalsis by direct action on the smooth muscle of the intestine. They generally produce bowel movement in 6 to 12 hours. Indications And Clinical Uses: For the overnight…

EVISTA™ Lilly Raloxifene HCl Selective Estrogen Receptor Modulator Action And Clinical Pharmacology: Raloxifene is a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. The SERM profile of raloxifene includes estrogen agonist effects on bone and lipid metabolism but not in uterine or breast tissues. Pharmacokinetics: The disposition of raloxifene has been evaluated in 276 postmenopausal women in conventional clinical pharmacology studies and in more than…

EXOSURF® NEONATAL Glaxo Wellcome Colfosceril Palmitate Synthetic Lung Surfactant Action And Clinical Pharmacology: Surfactant deficiency is an important factor in the development of the neonatal respiratory distress syndrome (RDS). Natural surfactant, a combination of lipids and apoproteins, exhibits not only surface tension reducing properties (conferred by the lipids), but also rapid spreading and adsorption (conferred by the apoproteins). The major fraction of the lipid component of natural surfactant is colfosceril…

EURAX® Novartis Consumer Health Crotamiton Antipruritic Indications And Clinical Uses: To relieve itching in most types of dermatosis, notably: atopic dermatitis, chickenpox, contact dermatitis, creeping eruption, dermatitis herpetiformis, dermatitis medicamentosa, dermatophytosis, eczema, insect bites, intertrigo, lichen planus, neurodermatitis, neurotic excoriation, pityriasis rosea, poison ivy dermatitis, pruritus ani, scroti and vulvae, psoriasis, seborrheic dermatitis, senile pruritus, sunburn, urticaria, varicose eczema. Contra-Indications: Acutely inflamed skin or raw, weeping areas. Hypersensitivity to crotamiton….