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Brand Names: HIBITANE® Skin Cleanser Manufacturer: Zeneca Generic Name: Chlorhexidine Gluconate Use: Antibacterial Skin Cleanser Action And Clinical Pharmacology Chlorhexidine is effective against a wide range of gram-negative and gram-positive vegetative bacteria, yeasts, dermatophyte fungi and lipophilic viruses. It is inactive against bacterial spores except at elevated temperatures. Because of its cationic nature, chlorhexidine binds strongly to skin, mucosa and other tissues and is thus very poorly absorbed. No detectable blood levels have…

HEPARINS: LOW MOLECULAR WEIGHT General Monograph, Dalteparin Enoxaparin Nadroparin Tinzaparin Anticoagulant Action And Clinical Pharmacology: Low molecular weight heparins (LMWHs) are fragments of heparin produced by enzymatic or chemical depolymerization. They have an average molecular weight of 4 000 to 5 000 daltons (range 1 000 to 10 000 daltons) which is approximately one-third that of standard heparin. Most heparin molecules with molecular weights smaller than 5 400 daltons are…

HEXABRIX® 200 HEXABRIX® 320 Mallinckrodt Ioxaglate Meglumine – Ioxaglate Sodium Radiopaque Medium Action And Clinical Pharmacology: Following intravascular injection, Hexabrix is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine. The pharmacokinetics of intravascularly administered radiopaque contrast media are usually best described by a two compartment model with a rapid alpha phase for drug distribution and a slower beta phase for drug elimination….

HEXADROL® PHOSPHATE INJECTION Organon Teknika Dexamethasone Sodium Phosphate Corticosteroid Action And Clinical Pharmacology: After administration of the injection, dexamethasone sodium phosphate is rapidly converted into dexamethasone. This is a synthetic glucocorticoid which has 7 times the anti-inflammatory potency of prednisolone. Like other glucocorticoids, dexamethasone also has antiallergic, antitoxic, antishock, antipyretic and immunosuppressive properties. Dexamethasone has practically no water and salt-retaining properties and is, therefore, particularly suitable for use in patients…

HEXALEN® Lilly Altretamine Antineoplastic Agent Action And Clinical Pharmacology: Altretamine, better known in the scientific literature as hexamethylmelamine (HMM), is a synthetic cytotoxic antineoplastic s-triazine derivative. While altretamine bears structural similarity to, and cross-reactivity with, triethylenemelamine (TEM), a classical alkylating agent, evidence demonstrating altretamine to be an alkylating agent is not conclusive. Altretamine does not consistently demonstrate cross-resistance with classical alkylating agents used in rodent tumors or in human cancer…

HALOTESTIN® Pharmacia & Upjohn Fluoxymesterone Androgenic – Anabolic Steroid Action And Clinical Pharmacology: Endogenous androgens are responsible for normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body…

HAVRIX™ SmithKline Beecham Hepatitis A Vaccine (Inactivated) Active Immunization Agent against infection by Hepatitis A virus Action And Clinical Pharmacology: Hepatitis A vaccine (inactivated) confers immunity against hepatitis A virus (HAV) infection by inducing the production of specific anti-HAV antibodies. In clinical studies involving subjects of 18 to 50 years of age, specific humoral antibodies against HAV were detected in more than 88% of vaccinees at day 15 and 99%…

GLUCODEX® Rougier Dextrose Diagnostic Agent For Diabetes Indications And Clinical Uses: Glucose tolerance test. Contra-Indications: In patients with the glucose-galactose malabsorption syndrome. Precautions: Dextrose should be administered with care to patients with diabetes insipidus. Drug Interactions: Purgatives may inhibit the intestinal absorption of dextrose. Adverse Reactions: Concentrated dextrose solutions given by mouth may cause nausea and vomiting. Dosage: Glucose tolerance test: Adults (except pregnant women): 75 g. Children: 1.75 g/kg…

GASTROLYTE® Rhône-Poulenc Rorer Electrolytes – Dextrose Antidiarrheal Indications And Clinical Uses: For the management of watery diarrhea of varying types, including gastroenteritis and oral correction of fluid and electrolyte loss in infants, children and adults. Contra-Indications: There are no known contraindications to this product. Manufacturers’ Warnings In Clinical States: Cow’s milk and artificial milk feeds in infants should be stopped for 24 hours and gradually introduced when the diarrhea has…

GAS-X® GAS-X® EXTRA STRENGTH Novartis Consumer Health Simethicone Antiflatulent Action And Clinical Pharmacology: The active ingredient, simethicone acts in the stomach and intestines to disperse and reduce the formation of mucus-trapped gas bubbles. This defoaming action reduces the surface tension of gas bubbles so that they are more easily eliminated. Indications And Clinical Uses: Effective antiflatulent that helps relieve the discomfort caused by excess gas in the stomach and intestinal…