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LIVOSTIN™ EYE DROPS CIBA Vision Levocabastine HCl Histamine H1-antagonist Action And Clinical Pharmacology: Levocabastine is a potent, fast-acting and highly selective histamine H1-antagonist with a sustained duration of action. Within 10 to 15 minutes of topical application to the eyes, levocabastine inhibits: itching, redness and chemosis induced by conjunctival provocation with histamine; itching, redness, chemosis, eyelid swelling, and tearing induced by conjunctival provocation with allergens; and itching and redness induced…

LIPACTIN® Novartis Consumer Health Heparin Sodium – Zinc Sulfate Symptomatic Treatment of Herpes Simplex I Action And Clinical Pharmacology: Lipactin is composed of heparin and zinc for topical application. Topical application of heparin produces accumulation of the heparin molecules in the corium of the skin while insignificant amounts are absorbed through the skin. Oral administration of heparin is associated with negligible anticoagulant effect as heparin is immediately metabolized in the…

LIPIDIL MICRO® Fournier Fenofibrate (Micronized) Lipid Metabolism Regulator Action And Clinical Pharmacology: Fenofibrate lowers elevated serum lipids by decreasing the low density lipoprotein (LDL) fraction rich in cholesterol and the very low density lipoprotein (VLDL) fraction rich in triglycerides. In addition, fenofibrate increases the high density lipoprotein (HDL) cholesterol fraction. Fenofibrate appears to have a greater depressant effect on the very low density lipoproteins (VLDL) than on the low density…

LIPISORB® Mead Johnson Therapeutic Nutrient Indications And Clinical Uses: A nutritionally complete liquid diet specifically designed for patients with fat malabsorption (e.g., inflammatory bowel disease, cystic fibrosis, short bowel syndrome and HIV infection). It provides complete vitamins and minerals with a readily absorbed fat blend. This vanilla flavored beverage can be fed orally or as a tube feeding. tag_DosageDosage Dosage And Administration: As prescribed by a physician. Tube feeding may…

LIPITOR™ Parke-Davis Atorvastatin Calcium Lipid Metabolism Regulator Action And Clinical Pharmacology: Atorvastatin is a synthetic lipid-lowering agent. It is a selective, competitive inhibitor of 3-hydroxy- 3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. Atorvastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and by increasing…

LIDOSPORIN® Cream LIDOSPORIN® Ear Drops Warner-Lambert Consumer Healthcare Polymyxin B Sulfate – Gramicidin – Lidocaine HCl Polymyxin B Sulfate – Lidocaine HCl Antibiotic – Anesthetic – Antipruritic Indications And Clinical Uses: Cream: Topical relief of pain and itching; also for the treatment and prevention of infections in minor cuts, wounds, and burns. Ear Drops: The prevention of exacerbations and treatment of infection due to susceptible organisms, relief of pain and…

LINCOCIN® Pharmacia & Upjohn Lincomycin HCl Monohydrate Antibiotic Action And Clinical Pharmacology: The mode of action of lincomycin is the inhibition of protein synthesis by the inhibition of the binding of aminoacyl sRNA to the messenger ribosome complex at the 50S ribosomal unit. Lincomycin is absorbed rapidly after oral administration, reaching peak levels in 2 to 4 hours. Levels above the minimum inhibitory concentration for most gram-positive organisms are maintained…

LIORESAL® Novartis Pharmaceuticals Baclofen Muscle Relaxant – Antispastic Action And Clinical Pharmacology: Baclofen’s precise mechanisms of action are not fully known. It inhibits both monosynaptic and polysynaptic reflexes at the spinal level, probably by hyperpolarization of afferent terminals, although actions at supraspinal sites may also occur and contribute to its clinical effect. Although baclofen is an analog of the putative inhibitory neurotransmitter gamma-aminobutyric acid (GABA), there is no conclusive evidence…

LIORESAL® Intrathecal Novartis Pharmaceuticals Baclofen Muscle Relaxant – Antispastic Action And Clinical Pharmacology: The precise mechanisms of action of baclofen as a muscle relaxant and antispastic agent are not fully understood. Baclofen inhibits both monosynaptic and polysynaptic reflex transmission at the spinal level, possibly by decreasing excitatory neurotransmitter release from primary afferent terminals. Actions at supraspinal sites may also contribute to its clinical effect. Baclofen is an analogue of the…

LIDEMOL® Medicis Fluocinonide Topical Corticosteroid Indications And Clinical Uses: For topical therapy of corticosteroid-responsive acute and chronic skin eruptions where an anti-inflammatory, anti-allergenic and antipruritic activity in the topical management is required. Contra-Indications: Untreated bacterial, tubercular, fungal and most viral lesions of the skin (including herpes simplex, vaccinia and varicella) and untreated purulent bacterial infections. Hypersensitivity to any of the components. Manufacturers’ Warnings In Clinical States: Pregnancy and Lactation: The…