You searched for : 'K'

PANTOTHENIC ACID General Monograph, Vitamin B5 Vitamin Pharmacology: Pantothenic acid is a water-soluble, B complex vitamin. It is a precursor of coenzyme A and is essential for acetylation reactions in gluconeogenesis, carbohydrate and lipid metabolism, and in the synthesis of steroid hormones, porphyrins, acetylcholine and other compounds. Pantothenic acid is a required nutrient, but is so widely distributed that deficiency in humans is unlikely. Pantothenic acid deficiency is usually found…

PANTOLOC™ Solvay Pharma/Byk Canada Pantoprazole H KATPase Inhibitor Action And Clinical Pharmacology: Pantoprazole is a specific inhibitor of the gastric H KATPase enzyme (the proton pump) that is responsible for acid secretion by the parietal cells of the stomach. Pantoprazole is a substituted benzimidazole that accumulates in the acidic environment of the parietal cells after absorption. Pantroprazole is then converted into the active form, a cyclic sulfenamide, which binds to…

PARAFON FORTE® C8 Johnson & Johnson• Merck Chlorzoxazone – Acetaminophen – Codeine Phosphate Analgesic – Muscle Relaxant Action And Clinical Pharmacology: Parafon Forte C8 combines the muscle-relaxant effect of chlorzoxazone with acetaminophen, a well-known analgesic, and codeine, a centrally-acting narcotic analgesic. Chlorzoxazone is a centrally acting agent for painful musculoskeletal conditions. Data available from animal experiments, as well as human study, indicate that chlorzoxazone acts primarily at the level of…

PARAFON FORTE® Johnson & Johnson• Merck Chlorzoxazone – Acetaminophen Muscle Relaxant – Analgesic Action And Clinical Pharmacology: Parafon Forte tablets combine the muscle-relaxant effect of chlorzoxazone with acetaminophen, a well-known analgesic. Chlorzoxazone is a centrally acting agent for painful musculoskeletal conditions. Data available from animal experiments, as well as human study, indicate that chlorzoxazone acts primarily at the level of the spinal cord and subcortical areas of the brain where…

PAMPRIN® PAMPRIN® Extra Strength PAMPRIN® PMS Chattem Pamabrom – Pyrilamine Maleate – Acetaminophen Diuretic – Antihistamine – Analgesic Indications And Clinical Uses: For temporary relief of symptoms accompanying premenstrual syndrome such as cramps, headache, irritability, backache and mild to moderate aches and pains. To reduce the temporary excess water frequently associated with the premenstrual period. Pamprin is most effective if taken at the first sign of discomfort, usually a few…

PANCREASE® PANCREASE® MT Janssen-Ortho Pancrelipase Digestant Action And Clinical Pharmacology: The enteric-coated microtablets resist gastric inactivation and deliver predictable, high levels of biologically active pancreatic enzymes (lipase, amylase, and protease) into the duodenum. The enzymes catalyze the hydrolysis of fats into glycerol and fatty acids, proteins into proteoses and derived substances, and starch into dextrins and sugars. Pharmacokinetics: Absorption: The intestinal bioavailability of Pancrease MT 16 capsules was determined, in…

PANOCAINE® Hoechst Marion Roussel Benzocaine – Tetracaine HCl Oral Topical Anesthetic Action And Clinical Pharmacology: Panocaine is a local anesthetic of the ester type which rapidly produces surface anesthesia following application to the mucosa of the oral cavity in clinical dentistry. Panocaine has a short duration of action and is ineffective when applied to intact skin. Indications And Clinical Uses: For use in the oral cavity for minimizing the pain…

PANECTYL® Rhône-Poulenc Rorer Trimeprazine Tartrate Antipruritic – Antihistamine Action And Clinical Pharmacology: Trimeprazine is a propylamino phenothiazine derivative with reduced central activity and enhanced antihistaminic and antipruritic effects. It is a potent histamine antagonist. Trimeprazine possesses sedative properties, and is active in suppressing apomorphine induced vomiting in the dog. No evidence of teratogenic effect has been demonstrated in animal studies. Indications And Clinical Uses: Pruritus regardless of site or etiology….

Brand Names: PALAFER® Manufacturer: SmithKline Beecham Generic Name: Ferrous Fumarate Use: Anemia Therapy Indications And Clinical Uses Increased iron requirements as in childhood, adolescence, and pregnancy; blood losses, overt or occult. Characterized microcytic hypochromic anemia; faulty iron absorption following gastrectomy; iron loss due to menstruation, sub-clinical iron deficiencies in adolescent girls due to precarious iron balance, and geriatrics. Contraindications Hemosiderosis, hemochromatosis. Iron compounds are also contraindicated in the treatment of…

PALUDRINE® Wyeth-Ayerst Proguanil HCl Antimalarial Action And Clinical Pharmacology: Proguanil is metabolized in the body to the antimalarial drug cycloguanil, a triazine derivative, which inhibits plasmodial dihydrofolate reductase thus indirectly inhibiting synthesis of nucleic acids in the parasite. Proguanil, like pyrimethamine, is active against pre-erythrocytic forms and is a slow blood schizontocide. It also has some sporonticidal activity, rendering the gametocytes noninfective to the mosquito vector. Pharmacokinetics: Proguanil is well…