General Information Brand Name: ACCOLATE® Manufacturer: Zeneca Scientific Name: Zafirlukast Application: Leukotriene Receptor Antagonist Pharmacology Zafirlukast is a selective and competitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4), components of slow-reacting substance of anaphylaxis (SRSA). Cysteinyl leukotriene production and receptor occupation have been correlated with the pathophysiology of asthma, including airway edema, smooth muscle constriction, and altered cellular activity associated with the inflammatory process, which contribute to…
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Accolate (Leukotriene)
(Pharmaceutical)Abbokinase
(Pharmaceutical)General Information Brand Name: ABBOKINASE® Manufacturer: Abbott Scientific Name: Urokinase Application: Fibrinolytic Pharmacology Urokinase acts on the endogenous fibrinolytic system. It converts plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen. I.V. infusion of urokinase in doses recommended for lysis of pulmonary embolism is followed by increased fibrinolytic activity. This effect disappears within a few hours after discontinuation, but a decrease in plasma levels of fibrinogen…
Ginkgo Biloba
(Herbal)General Information Common Name: Ginkgo Biloba Latin Name: Ginkgo Biloba Family: gingkoaceae Other Names: Maidenhair tree. Indications & Historical Uses Ginkgo biloba is one of the world’s oldest living tree species. It is considered a sacred tree in China, and has been used in oriental medicine since ancient times, mainly to improve brain function, and for respiratory ailments. Currently, its main indications are: Macular degeneration of retina; Allergies; Asthma; Cerebral…
Yohimbine (Welcker-Lyster)
(Herbal)YOHIMBINE Welcker-Lyster Sympatholytic Indications And Clinical Uses: As an alpha-adrenergic blocking agent. Contra-Indications: Cardiac or renal disease. Precautions: Yohimbine may cause hypotension. It should not be administered to geriatric patients, psychiatric patients or cardiorenal patients with a history of gastric or duodenal ulcer. Symptoms And Treatment Of Overdose: Symptoms and Treatment: Conduct gastric lavage and administer activated charcoal (4 tablespoonfuls/500 mL of water). Treat excitation or convulsions with a barbiturate….
Skin Care
(Illness)Only healthy clean skin can perform its functions correctly. Proper skin care prevents skin diseases and premature aging. Types of skin diseases: In general, any manifestations on the skin may be a reaction to any factors. For example, acne is a consequence of hormonal disorders, rosacea can develop against the background of prolonged antibiotic therapy, fans of beaches, tanning salons and saunas can face couperosis. Classifying skin ailments is very…
Kava Kava (Kavalactones)
(Pharmaceutical)General Information Common Name: Kava Kava Latin Name: Piper Methysticum Family: Piperaceae Other Names: Awa. Intoxicating pepper. Kew. Tonga. Indications & Historical Uses Anxiety (stress reliever) – induces physical and mental relaxation. Insomnia. Restless leg syndrome. Chronic fatigue syndrome. Menopausal symptoms. Bladder anti-spasmodic. Contraindications & Precautions Not to be taken during pregnancy or lactation. Exercise caution with any concurrent illness. Contraindicated in severe depression. (See Caution). Adverse Effects: Regular use of Kava…
Zephiran (Benzalkonium Chloride)
(Pharmaceutical)ZEPHIRAN® Sanofi Benzalkonium Chloride Topical Antiseptic Indications And Clinical Uses: Antisepsis of skin and mucous membranes and as a disinfectant in surgery, obstetrics and gynecology, urology, ophthalmology, otorhinolaryngology and general practice. Also may be used as a disinfectant for hospital utensils and other environmental surfaces and for disinfection and storage of ampuls, thermometers, metal instruments and catheters. Contra-Indications: Incompatible with soap and anionic detergents. Use in occlusive dressings, casts and…
Zaditen (Ketotifen Fumarate)
(Pharmaceutical)ZADITEN® Novartis Ketotifen Fumarate Pediatric Asthma Prophylactic – Antiallergic Agent Action And Clinical Pharmacology: Ketotifen is a nonbronchodilator antiasthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators, and thereby exerts antiallergic activity. Preclinical studies indicated that ketotifen’s anti-H1 effect seems to be distinct from its antiallergic properties. The effectiveness of ketotifen in the chronic management of mild atopic pediatric asthma has been shown in…
Vitamin K
(Pharmaceutical)VITAMIN K General Monograph, Phytonadione Hypoprothrombinemia Therapy Action And Clinical Pharmacology: Vitamin K compounds are fat soluble naphthoquinones. Phytonadione (vitamin K1) and vitamin K2 occur in a variety of natural materials and are synthesized by certain bacteria in the gastrointestinal tract; however, commercially prepared phytonadione is synthetically produced. Phytonadione possesses essentially the same type and degree of activity as naturally occurring vitamin K1. Vitamin K is necessary for synthesis in…
Visken (Pindolol)
(Pharmaceutical)VISKEN® Novartis Pharmaceuticals Pindolol Antihypertensive – Antianginal Action And Clinical Pharmacology: Pindolol is a beta-adrenergic-receptor-blocking agent which possesses partial agonist activity (intrinsic sympathomimetic activity – I.S.A.). Hypertension: The mechanism of the antihypertensive effect of pindolol has not been established. Among the factors that may be involved are: competitive ability to antagonize catecholamine-induced tachycardia at the beta-receptor sites in the heart, thus decreasing cardiac output; a reduction in total peripheral resistance;…