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AKINETON® Knoll Biperiden HCl Anticholinergic – Antiparkinson Agent Action And Clinical Pharmacology: Biperiden is an anticholinergic agent which acts primarily on the CNS. Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems. Accordingly, the mechanism of action of centrally active anticholinergic drugs, such as biperiden, is considered to relate to competitive antagonism of acetylcholine at the cholinergic receptors in the corpus striatum, which…

ADEKs® Pediatric Drops ADEKs® Tablets Axcan Pharma Multiple Vitamins – Zinc Sulfate Multiple Vitamins – Zinc Oxide Multiple Vitamin – Mineral Supplement Action And Clinical Pharmacology: Deficiencies of one or more of the fat-soluble vitamins may occur in the presence of steatorrhea or other malabsorption, hepatic dysfunction, protein malnutrition, zinc deficiency, and very low fat diets. As with all vitamins, adequate levels are essential to good health and proper growth….

ADEKs® Pediatric Drops ADEKs® Tablets Axcan Pharma Multiple Vitamins – Zinc Sulfate Multiple Vitamins – Zinc Oxide Multiple Vitamin – Mineral Supplement Action And Clinical Pharmacology: Deficiencies of one or more of the fat-soluble vitamins may occur in the presence of steatorrhea or other malabsorption, hepatic dysfunction, protein malnutrition, zinc deficiency, and very low fat diets. As with all vitamins, adequate levels are essential to good health and proper growth….

ACULAR® Allergan Ketorolac Tromethamine Topical Anti-inflammatory Action And Clinical Pharmacology: Ketorolac is a nonsteroidal, anti-inflammatory agent demonstrating analgesic and anti-inflammatory activity. At concentrations of 0.02 to 0.5%, ketorolac solution did not irritate the eyes of rats, dogs and monkeys. Up to 4% concentrations were nonirritating in albino rabbits. Ketorolac has demonstrated anti-inflammatory activity when applied topically in several animal models of ocular inflammation. The compound significantly inhibited the inflammatory response…

ABBOKINASE® OPEN-CATH® Abbott Urokinase Fibrinolytic Action And Clinical Pharmacology: Urokinase acts on the endogenous fibrinolytic system. It converts plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen. When used as directed for i.v. catheter clearance only small amounts of urokinase may reach the circulation; therefore, therapeutic serum levels are not expected to be achieved. Nevertheless, one should be aware of the clinical pharmacology of urokinase. I.V….

ABBOKINASE® Abbott Urokinase Fibrinolytic Action And Clinical Pharmacology: Urokinase acts on the endogenous fibrinolytic system. It converts plasminogen to the enzyme plasmin. Plasmin degrades fibrin clots as well as fibrinogen. I.V. infusion of urokinase in doses recommended for lysis of pulmonary embolism is followed by increased fibrinolytic activity. This effect disappears within a few hours after discontinuation, but a decrease in plasma levels of fibrinogen and plasminogen and an increase…

ACCOLATE® Zeneca Zafirlukast Leukotriene Receptor Antagonist Action And Clinical Pharmacology: Zafirlukast is a selective and competitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4), components of slow-reacting substance of anaphylaxis (SRSA). Cysteinyl leukotriene production and receptor occupation have been correlated with the pathophysiology of asthma, including airway edema, smooth muscle constriction, and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of…

ASPIRIN® BACKACHE Bayer Consumer ASA – Methocarbamol Analgesic – Muscle Relaxant Indications And Clinical Uses: Provides effective relief of back pain by reducing muscle spasms and relaxing tense back and neck muscles, thereby increasing mobility. Precautions: Consult a physician or pharmacist before taking this medication if you: have a predisposition to asthma, stomach problems, peptic ulcer, severe liver disease, gout, severe anemia or allergy to salicylates; have a history of…