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URISPAS® Pharmascience Flavoxate HCl Urinary Tract Antispasmodic Action And Clinical Pharmacology: Flavoxate is a papaverine-like smooth muscle relaxant. It exhibits, however, greater antispasmodic activity and is less toxic. The basic action of flavoxate is the relaxation of smooth muscle fibres of the urinary tract through a mechanism not yet defined. By counteracting smooth muscle spasms of the urinary tract, it relieves the pain and discomfort accompanying a variety of urological…

UROMITEXAN™ Bristol Mesna Uroprotector Action And Clinical Pharmacology: Mesna is rapidly and easily converted by autooxidation to its only metabolite disodium 2,2¢-dithio-bis ethane sulfonate (mesna disulfide, dimesna), forming a disulfide link. Following i.v. injection, only a small portion of the administered dose is detected in the blood as a reactive thiol compound (mesna). Mesna disulfide remains in the intravascular space and is rapidly forwarded to the kidney. In the renal…

UNIPHYL® Purdue Frederick Theophylline Bronchodilator Action And Clinical Pharmacology: Theophylline relaxes bronchial smooth muscle (particularly when the muscles are constricted); produces vasodilation except in cerebral vessels; stimulates the CNS including the respiratory center; stimulates cardiac muscle; produces diuresis and increases gastric acid secretion. In addition to its activity as a bronchodilator, theophylline may also stimulate mucociliary clearance, inhibit anaphylactic mediator release, suppress mediator induced inflammation and improve contractility of the…

ULTRAVIST® Berlex Canada Iopromide Nonionic Iodinated Radiographic Contrast Medium Action And Clinical Pharmacology: Iopromide is a nonionic iodinated radiographic contrast medium which is available in 3 stable, ready-to-use solutions of different concentrations. Following intravascular injection, iopromide provides radiographic opacification of the vasculature and extracellular space allowing diagnostic assessment of the limbs and internal organs. For example, after i.v. injection, opacification of the renal parenchyma begins within 1 minute. Excretion of…

URASAL® Carter Horner Hexamine Urinary Antiseptic Indications And Clinical Uses: Mild and chronic urinary tract infections, especially cystitis, prostatitis, urethritis. Symptoms And Treatment Of Overdose: Symptoms: Nausea, anorexia, pain on urination. Treatment: Gastric lavage or emesis. In children, induce emesis and if there is no immediate response, use gastric lavage. No known antidote. Dosage: 2 level teaspoonfuls in 240 mL of water 3 times a day before meals, or as…

UNIVOL® Carter Horner Magnesium Hydroxide – Aluminum Hydroxide Antacid Indications And Clinical Uses: For the symptomatic relief of hyperacidity associated with peptic ulcer, gastritis, esophagitis, heartburn or hiatal hernia. Contra-Indications: Not to be given to patients who are severely debilitated or suffering from renal failure. Alkalosis, hypermagnesemia. Manufacturers’ Warnings In Clinical States: Do not take more than 80 mL during a 24-hour period. Do not take the maximum dosage for…

ULTRADOL™ Procter & Gamble Pharmaceuticals Etodolac Nonsteroidal Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory analgesic and antipyretic properties in animal models. The pharmacological actions of etodolac are thought to be related to inhibition of prostaglandin biosynthesis at the site of inflammation. Ultradol is a racemic mixture of R- and S-etodolac. As with other NSAIDs, it has been demonstrated in animals…

ULTRAVATE™ Preparations Westwood-Squibb Halobetasol Propionate Topical Corticosteroid Indications And Clinical Uses: Halobetasol cream and ointment are high to super-high potency topical corticosteroids indicated for the relief of inflammatory manifestations of resistant or severe psoriasis and corticosteroid-responsive dermatoses. These products are not recommended for use in children. Contra-Indications: In patients who are hypersensitive to halobetasol, to other corticosteroids or to any of the ingredients in these products. Halobetasol cream and ointment…

ULTRASE® MT Axcan Pharma Pancrelipase Digestive Enzymes Action And Clinical Pharmacology: Pancrelipase capsules are designed to prevent inactivation by gastric acid thereby resulting in the delivery of predictable, high levels of biologically active enzymes into the duodenum. The enzymes catalyze the hydrolysis of fats into glycerol and fatty acids, starch into dextrins and sugars, and protein into proteoses and derived substances. Indications And Clinical Uses: For patients with partial or…

TRIACOMB® Technilab Triamcinolone Acetonide-Nystatin-Neomycin Sulfate Gramicidin Corticosteroid-Antifungal-Antibacterial Availability And Storage: Each g of cream contains: triamcinolone acetonide USP 1 mg, nystatin USP 100 000 units, neomycin base (in sulfate) USP 2.5 mg and gramicidin USP 0.25 mg in a vanishing cream base. Nonmedicinal ingredients: aluminum hydroxide, ceteareth-20, cetearyl alcohol, glyceryl monostearate, glyceryl stearate, methylparaben, petrolatum, polysorbate 60, propylene glycol, propylene glycol monostearate, propylparaben, purified water, sorbitol and titanium dioxide. Jars…