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VAQTA® MSD Hepatitis A Vaccine (Purified Inactivated) Vaccine Action And Clinical Pharmacology: Hepatitis A vaccine, purified inactivated is an inactivated whole virus vaccine which has been shown to induce antibody to hepatitis A virus protein. Disease Epidemiology: Hepatitis A virus is one of several hepatitis viruses that cause a systemic infection with pathology in the liver. The incubation period ranges from approximately 20 to 50 days. While the course of…

VASERETIC® Frosst Enalapril Maleate – Hydrochlorothiazide Angiotensin Converting Enzyme Inhibitor – Diuretic Action And Clinical Pharmacology: Vaseretic combines the action of an angiotensin converting enzyme inhibitor, enalapril maleate, and that of a diuretic, hydrochlorothiazide. Enalapril Maleate: Angiotensin converting enzyme (ACE) is a peptidyl dipeptidase which catalyzes the conversion of angiotensin I to the pressor substance, angiotensin II. After absorption, enalapril, a pro-drug, is hydrolyzed to enalaprilat, its active metabolite, which…

VALIUM® ROCHE® INJECTION Roche Diazepam Anxiolytic – Sedative Action And Clinical Pharmacology: Diazepam is an anxiolytic-sedative drug useful in the symptomatic relief of anxiety and tension states. It has also adjunctive value in the relief of certain neurospastic conditions and in certain cases, its anticonvulsant activity has been found useful in controlling status epilepticus. Peak blood levels after the i.v. administration of diazepam injection are reached within 15 minutes as…

VALTREX® Glaxo Wellcome Valacyclovir HCl Antiviral Agent Action And Clinical Pharmacology: Mechanism of Action: Valacyclovir is the L-valyl ester and a pro-drug of the antiviral drug acyclovir. Valacyclovir is rapidly converted to acyclovir, which has in vitro and in vivo inhibitory activity against human herpes viruses including herpes simplex virus types 1 (HSV-1) and 2 (HSV-2), and varicella-zoster virus (VZV). The inhibitory activity of acyclovir is highly selective due to…

VAMIN® N Pharmacia & Upjohn Amino Acids – Electrolytes Nutritive and Electrolyte Supplements for I.V. Infusion Action And Clinical Pharmacology: Vamin N supplies electrolytes and essential, semi-essential and nonessential L-amino acids for synthesis of body proteins. Nitrogen retention can be promoted by adjusting the energy to nitrogen ratio with simultaneous administration of lipids and/or hypertonic sugar solutions according to the needs of the patient. tag_IndicationsIndications Indications And Clinical Uses: For…

VAMIN® 18 ELECTROLYTE-FREE Pharmacia & Upjohn Amino Acids Nutritive and Electrolyte Supplements for I.V. Infusion Action And Clinical Pharmacology: Vamin 18 Electrolyte-Free acts as a source for protein synthesis in patients with insufficient enteral supply of precursors for protein synthesis. The solution contains all 18 essential and nonessential amino acids. The balance between the amino acids is such that positive nitrogen balance can be achieved in the postoperative period. When…

VALISONE-G® Schering Betamethasone Valerate – Gentamicin Sulfate Topical Corticosteroid – Antibiotic Action And Clinical Pharmacology: Valisone-G provides the combined anti-inflammatory, anti-allergic, and antipruritic actions of betamethasone valerate with the antibacterial topical effect of gentamicin. Indications And Clinical Uses: The topical management of secondarily infected allergic or inflammatory dermatoses responsive to corticosteroid therapy, such as contact dermatitis, seborrheic dermatitis, neurodermatitis, intertrigo, exfoliative dermatitis, stasis dermatitis and psoriasis. Secondary infections caused by…

VALIUM® ROCHE® ORAL Roche Diazepam Anxiolytic – Sedative Action And Clinical Pharmacology: Diazepam is an anxiolytic-sedative drug useful in the symptomatic relief of anxiety and tension states. It has also adjunctive value in the relief of certain neurospastic conditions. Peak blood levels after oral administration of diazepam are reached within 1 to 2 hours after single oral dosing. The acute half-life is 6 to 8 hours with a slower decline…

VALISONE® Scalp Lotion Schering Betamethasone Valerate Topical Corticosteroid Indications And Clinical Uses: The management of dermatoses of the scalp. May also be used in corticosteroid responsive dermatoses. Contra-Indications: See Celestoderm-V. Manufacturers’ Warnings In Clinical States: This lotion contains isopropyl alcohol, and may cause stinging or burning upon application to abraded or sun-burned skin. Do not use in or near the eyes. Precautions and Adverse Effects: See Celestoderm-V. Dosage: Apply a…

URECHOLINE® Frosst Bethanechol Chloride Parasympathomimetic Agent Action And Clinical Pharmacology: Bethanechol acts principally by producing the effects of stimulation of the parasympathetic nervous system. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone, and often restores rhythmic peristalsis. Stimulation of the parasympathetic nervous system releases acetylcholine at the nerve endings….