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CORTONE® Tablets MSD Cortisone Acetate Corticosteroid Action And Clinical Pharmacology: Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Cortisone is a natural product of the adrenal cortex. Cortisone acetate is a synthetic steroid with the basic actions and effects of other glucocorticoids. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency…

CORTATE® 0.5 % CORTATE® 1 % Schering Hydrocortisone Topical Corticosteroid Indications And Clinical Uses: For temporary relief of minor skin irritations, itching and rashes due to eczema, dermatitis, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics and jewellery. Manufacturers’ Warnings In Clinical States: For external use only. Do not use in or around the eyes. Do not apply to large areas of the body. Do not use…

CORTEF® Pharmacia & Upjohn Hydrocortisone Corticosteroid Action And Clinical Pharmacology: Hydrocortisone (cortisol) is a corticosteroid secreted by the adrenal cortex. In physiologic doses, it is administered to replace deficient endogenous hormones. In larger (pharmacologic) doses, hydrocortisone decreases inflammation and suppresses the immune response. It stimulates erythroid cells of the bone marrow, prolongs survival time of erythrocytes and platelets, and produces neutrophilia and eosinopenia. Hydrocortisone promotes protein catabolism, gluconeogenesis, and redistribution…

CORTIFOAM™ R & C Hydrocortisone Acetate Rectal Anti-inflammatory Action And Clinical Pharmacology: Action appears to be due to a local anti-inflammatory effect of hydrocortisone on the mucosa rather than as a result of a systemic effect. Indications And Clinical Uses: As adjunctive therapy in the treatment of ulcerative colitis of the sigmoid colon, proctosigmoiditis, granular proctitis and ulcerative proctitis. Contra-Indications: To the use of intrarectal steroids include, obstruction, abscess, perforation,…

CORTENEMA® Axcan Pharma Hydrocortisone Glucocorticoid Indications And Clinical Uses: An adjunct in the treatment of nonspecific inflammatory diseases involving the rectum, sigmoid and left colon such as idiopathic ulcerative colitis, ulcerative proctitis, regional enteritis (granulomatous colitis) with left side involvement, proctitis, proctocolitis, and radiation proctitis. Contra-Indications: Local contraindications to the use of intrarectal steroids include obstruction, abscess, perforation, peritonitis, fresh intestinal anastomoses, extensive fistulas and sinus tracts. Active tuberculosis (active,…

BURINEX® Leo Bumetanide Diuretic Action And Clinical Pharmacology: Bumetanide is a loop diuretic. The diuretic effect of bumetanide results largely from the inhibition of sodium reabsorption in the ascending limb of the loop of Henle. This is shown by a marked reduction in freewater clearance during hydration and tubular solute-free water reabsorption during hydropenia. Bumetanide may have an additional action in the proximal tubule, since phosphaturia has been observed during…

BUSPAR® Bristol Buspirone HCl Anxiolytic Action And Clinical Pharmacology: Buspirone is a psychotropic drug with selective anxiolytic properties which belongs chemically to the class of compounds known as the azaspirodecanediones, not chemically or pharmacologically related to benzodiazepines. Buspirone shares some of the properties of the benzodiazepines and the neuroleptics, as well as demonstrating other pharmacological action. Buspirone attenuates punishment suppressed behavior in animals and exerts a taming effect, but is…

BUTISOL® SODIUM Carter Horner Butabarbital Sodium Sedative – Hypnotic Indications And Clinical Uses: A daytime sedative when mild sedation is required for relief of symptoms of anxiety or tension resulting from emotional, physical, or situational stress. May be used in such conditions as: neuroses and anxiety-tension states, functional gastrointestinal disorders, peptic ulcer, menopausal syndrome, premenstrual tension, hyperthyroidism, essential hypertension, coronary artery disease, congestive heart failure, preoperative apprehension and insomnia. Contra-Indications:…

BREVICON® 0.5/35 Searle Norethindrone – Ethinyl Estradiol Oral Contraceptive Action And Clinical Pharmacology: Estrogen-progestogen combinations act primarily through the mechanism of gonadotropin suppression due to the estrogenic and progestational activity of their components. Although the primary mechanism of action is inhibition of ovulation, alterations in the cervical mucus and the endometrium may also contribute to effectiveness. tag_IndicationsIndications Indications And Clinical Uses: Prevention of pregnancy. Contra-Indications: History of or actual thrombophlebitis…

BRICANYL® Tablets BRICANYL® TURBUHALER® Astra Terbutaline Sulfate Bronchodilator Action And Clinical Pharmacology: Terbutaline produces bronchodilation by stimulation of the B2 adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of muscle fibres. This action is manifested by an increase in pulmonary function as demonstrated by FEV1 measurements. Terbutaline also produces a decrease in airway and pulmonary resistance. Following inhalation of terbutaline Turbuhaler, a significant improvement in pulmonary function measurements is…