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DEQUADIN® Preparations Roberts Dequalinium Chloride Antibacterial – Antifungal Indications And Clinical Uses: For the treatment of mouth and throat infections. Contra-Indications: Dequalinium chloride sensitivity. Precautions: If irritation persists or sensitization occurs, discontinue use and consult a physician. Adverse Reactions: Allergic reactions have been reported rarely. Dosage And Administration: Lozenges: 1 lozenge sucked slowly every 2 or 3 hours. In severe infections, increase frequency of administration. Oral Paint: Apply freely to…

DERMOVATE® Glaxo Wellcome Clobetasol 17-Propionate Topical Corticosteroid Action And Clinical Pharmacology: The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects. Topical corticosteroids such as clobetasol are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, antipruritic, and vasoconstrictive actions. However, while the physiologic, pharmacologic…

DESENEX® Novartis Consumer Health Undecylenic Acid – Zinc Undecylenate Antifungal Action And Clinical Pharmacology: Undecylenic acid is an antifungal agent, effective in the treatment of superficial fungal infections of the skin, such as tinea pedis (athlete’s foot), tinea cruris (jock itch) and tina corporis due to T. rubrum, T. mentagrophytes and E. flocossum, exclusive of nails and hair area. tag_IndicationsIndications Indications And Clinical Uses: For the treatment and prevention of…

DEPO-MEDROL® Pharmacia & Upjohn Methylprednisolone Acetate Glucocorticoid Action And Clinical Pharmacology: Depo-Medrol is a sterile aqueous suspension of the synthetic glucocorticoid methylprednisolone acetate. It has a strong and prolonged anti-inflammatory, immunosuppressive and antiallergic activity. Depo-Medrol can be administered i.m. for a prolonged systemic activity as well as in situ for a local treatment. The prolonged activity of Depo-Medrol is explained by the slow release of the active substance. Indications And…

DEPO-MEDROL® with Lidocaine Pharmacia & Upjohn Methylprednisolone Acetate – Lidocaine HCl Glucocorticoid with Local Anesthetic Action And Clinical Pharmacology: Methylprednisolone is an anti-inflammatory steroid. Estimates of the relative potencies of methylprednisolone and prednisolone range from 1.13 to 2.1 with an average of 1.5. In general the required daily dose of methylprednisolone can be estimated to be two-thirds (or 0.7) the required daily dose of prednisolone. While the effect of parenterally…

DEPO-PROVERA® Pharmacia & Upjohn Medroxyprogesterone Acetate Progestogen Action And Clinical Pharmacology: Medroxyprogesterone acetate is a long-acting progestational steroid (progestogen) derived from a natural source (soybeans). Its long duration of action is a result of slow absorption from the injection site. Depo-Provera does not contain estrogen. For conception control, medroxyprogesterone inhibits the secretion of gonadotropins which, in turn, prevents follicular maturation and ovulation, and results in endometrial thinning. Additional progestational effects…

DEPO-TESTOSTERONE CYPIONATE Pharmacia & Upjohn Testosterone Cypionate Androgen Action And Clinical Pharmacology: Qualitatively similar to testosterone and its esters in physiologic activity, testosterone cypionate has the advantage of prolonged effect. In hypogonadal males, the effect of a single injection of 200 to 400 mg of testosterone cypionate, was observed to be maintained for 2 to 4 weeks, which is 2 to 4 times longer than the effect produced by a…

DEMULEN® 30 DEMULEN® 50 Searle Ethynodiol Diacetate – Ethinyl Estradiol Oral Contraceptive Action And Clinical Pharmacology: Estrogen-progestogen combinations act primarily through the mechanism of gonadotropin suppression due to the estrogenic and progestational activity of their components. Although the primary mechanism of action is inhibition of ovulation, alterations in the cervical mucus and the endometrium may also contribute to effectiveness. Indications And Clinical Uses: Demulen 30: Prevention of pregnancy. Demulen 50:…

DENOREX® DENOREX® EXTRA STRENGTH Whitehall-Robins Coal Tar – Menthol – Chloroxylenol Antiseborrheic – Antipruritic Indications And Clinical Uses: Denorex: Relieves persistent dandruff flaking and itching. Denorex Extra Strength: Relieves persistent dandruff flaking, itching, psoriasis and seborrheic dermatitis. Precautions: Rinse thoroughly to avoid possible discoloration of light-colored hair. Do not use on wounds or abraded skin. Discontinue treatment if irritation develops. Avoid contact with eyes. For external use only. Dosage: Wet…

DEPEN® Carter Horner Penicillamine Chelating Agent Action And Clinical Pharmacology: As a chelating agent, penicillamine removes copper from the body. In vitro studies indicate that one atom of copper combines with 2 molecules of penicillamine. It would appear that 1 g of penicillamine should be followed by the excretion of about 200 mg of copper; however, the actual amount excreted is about 1% of this. Penicillamine also reduces excess cystine…