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MAJEPTIL® Rhône-Poulenc Rorer Thioproperazine Mesylate Neuroleptic Action And Clinical Pharmacology: Thioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. Indications And Clinical Uses: All types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic…

M-M-R® II MSD Measles, Mumps and Rubella Virus Vaccine, Live, Attenuated, MSD Std Action And Clinical Pharmacology: M-M-R II is for immunization against measles (rubeola), mumps, and rubella (German measles). One injection of M-M-R II consists of Attenuvax (Measles Virus Vaccine, Live, Attenuated, MSD Std), Mumpsvax (Mumps Virus Vaccine, Live, Attenuated, MSD Std) and Meruvax II (Rubella Virus Vaccine, Live, Attenuated, MSD Std). Clinical studies of 279 triple seronegative children,…

M.V.I.-12 (Multivitamin Infusion) Rhône-Poulenc Rorer Multivitamins Vitamin Supplement Indications And Clinical Uses: This formulation is indicated as daily multivitamin maintenance dosage for adults and children aged 11 and above receiving parenteral nutrition. It is also indicated in other situations where administration by the i.v. route is required. Such situations include surgery, (including pre- and post-operative parenteral nutrition), extensive burns, fractures and other trauma, severe infectious diseases and comatose states, which…

MAALOX H2 ACID CONTROLLER™ Novartis Consumer Health Famotidine Histamine H2 Receptor Antagonist Action And Clinical Pharmacology: Famotidine is a competitive inhibitor of histamine H2-receptors. The primary clinically important pharmacologic activity of famotidine is inhibition of gastric juice secretion. Famotidine reduces the acid and pepsin content, as well as the volume, of basal, nocturnal, and stimulated gastric secretion. Indications And Clinical Uses: In the treatment of the following conditions where a…

MYOFLEX® Bayer Consumer Triethanolamine Salicylate Topical Analgesic Indications And Clinical Uses: Analgesic rub for the temporary relief of aches and pains of muscles and joints associated with backache, lumbago, neck ache, arthritic or rheumatic pain, strains, sprains, pain of tendons and ligaments. Contra-Indications: Salicylate hypersensitivity. Manufacturers’ Warnings In Clinical States: For external use only. Use only as directed. Keep this and all other drugs out of the reach of children….

MYOTONACHOL® Glenwood Bethanechol Chloride Parasympathomimetic Agent Action And Clinical Pharmacology: Bethanechol acts principally by producing the effects of stimulation of the parasympathetic nervous system. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It stimulates gastric motility, increases gastric tone, and often restores rhythmic peristalsis. Stimulation of the parasympathetic nervous system releases acetylcholine at the nerve endings….

MYCOSTATIN® Preparations Squibb Nystatin Antifungal Antibiotic Indications And Clinical Uses: Oral: Prevention and treatment of fun of the oral cavity and esophagus, for intestinal candidiasis and for protection against candidal overgrowth during antimicrobial or corticosteroid therapy. Topical: Treatment of cutaneous or mucocutaneous mycotic infections caused by Candida (Monilia) species. Vaginal: Local treatment of vaginal mycotic infections caused by C. albicans (Monilia) and other Candida species and treatment of pregnant patients…

LYSODREN Bristol Mitotane Antineoplastic Action And Clinical Pharmacology: Mitotane is an adrenal cytotoxic agent, and can cause adrenal inhibition, apparently without cellular destruction. Its biochemical mechanism of action is unknown. Available data suggest that the drug modifies the peripheral metabolism of steroids as well as directly suppressing the adrenal cortex. In man, mitotane administration alters cortisol’s extra-adrenal metabolism, leading to a reduction in measurable 17-hydroxy corticosteroids, even though plasma corticosteroid…

LOZIDE® Servier Indapamide Hemihydrate Diuretic – Antihypertensive Agent Action And Clinical Pharmacology: Indapamide is a diuretic antihypertensive agent. The mechanism whereby indapamide exerts its action in the control of hypertension is not completely elucidated: both renal and extrarenal actions may be involved. The renal site of action is the proximal part of the distal tubule and the ascending part of Henle’s loop. Sodium and chloride ions are excreted in approximately…

LOTENSIN® Novartis Benazepril HCl Angiotensin Converting Enzyme Inhibitor Action And Clinical Pharmacology: Benazepril is an angiotensin converting enzyme (ACE) inhibitor which is used in the treatment of hypertension. Benazepril, after hydrolytic bioactivation to benazeprilat, inhibits angiotensin converting enzyme (ACE), a peptidyl dipeptidase catalyzing the conversion of angiotensin I to the vasoconstrictor angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex, leading to sodium resorption and potassium secretion…