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Mersyndol (Acetaminophen – Codeine)

(Pharmaceutical)

MERSYNDOL® with CODEINE Hoechst Marion Roussel Acetaminophen – Codeine Phosphate – Doxylamine Succinate Analgesic Action And Clinical Pharmacology: Acetaminophen is the major metabolite of phenacetin and acetanilid. Acetaminophen is an effective and fast-acting analgesic which acts centrally to relieve mild to moderate pain. Animal and clinical studies have shown acetaminophen to have antipyretic and analgesic activity equal to that of ASA. Unlike the salicylates, acetaminophen does not interfere with tubular…

Mesasal (5-Aminosalicylic Acid)

(Pharmaceutical)

MESASAL™ SmithKline Beecham 5-Aminosalicylic Acid Enteric Coated Lower Gastrointestinal Anti-inflammatory Action And Clinical Pharmacology: 5-Aminosalicylic acid (5-ASA) is considered to be the active component of sulfasalazine. Although its mode of action has not been definitely elucidated, 5-ASA is thought to have a topical anti-inflammatory effect which is produced by inhibition of prostaglandin and/or leukotriene synthesis. The tablets have an acrylic based resin coating which is specifically designed to release 5-ASA…

Merrem (Meropenem)

(Pharmaceutical)

MERREM® Zeneca Meropenem Antibiotic Action And Clinical Pharmacology: Meropenem is a broad spectrum, b-lactamase-resistant, carbapenem antibiotic for parenteral administration. The bactericidal activity of meropenem results from the inhibition of bacterial cell wall synthesis. Meropenem readily penetrates through the cell wall of most gram-positive and gram-negative bacteria to reach penicillin binding protein (PBP) targets. Its greatest affinity is for PBP 2 of E. coli, PBP 2 and 3 of P. aeruginosa…

Meritene

(Pharmaceutical)

MERITENE® Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: As a supplement or as a tube feeding, recommended whenever protein needs are increased and energy requirements are moderate. Meritene Powder provides 18 g protein and 275 kcal (1 150 kJ)/serving. Precautions: Not for parenteral use. Dosage And Administration: Oral: As a supplement with or between meals: 1 to 3 servings daily, 1 150 to 3 450 kJ (275 to 825…

Mellaril (Thioridazine HCl)

(Pharmaceutical)

MELLARIL® Novartis Pharmaceuticals Thioridazine HCl Tranquilizer – Antipsychotic Action And Clinical Pharmacology: The basic pharmacological profile of thioridazine is similar to that of other phenothiazines, but there are significant differences in the clinical spectrum when compared with other agents of this class. The distinctive features of thioridazine are its low propensity to cause extrapyramidal side effects and its low antiemetic activity. Thioridazine has a wide therapeutic margin. At low and…

Meningococcal Polysaccharide Vaccine

(Pharmaceutical)

MENINGOCOCCAL POLYSACCHARIDE VACCINE, GROUPS A, C, Y AND W-135 COMBINED, MENOMUNE® Connaught Vaccine Action And Clinical Pharmacology: Meningitis can be caused by a variety of microorganisms including several sero-groups of meningococci. This vaccine will not stimulate protection against infections caused by organisms other than Groups A, C, Y and W-135 meningococci. It has been demonstrated that the presence of human serum bactericidal antibodies to meningococcal antigens is strongly correlated with…

Medrol Veriderm (Methylprednisolone)

(Pharmaceutical)

MEDROL® VERIDERM® Cream Pharmacia & Upjohn Methylprednisolone Topical Glucocorticoid Indications And Clinical Uses: Noninfected dermatoses, including allergic dermatoses, pruritus ani and vulvae, atopic and seborrheic dermatitis and contact dermatitis, induced by poison ivy, cosmetics, chemicals or drugs. Contra-Indications: Tuberculosis of the skin, herpes simplex, vaccinia, varicella and other cutaneous infections for which an effective agent is not available for simultaneous application. Do not use in the eye or in patients…

Mefoxin (Cefoxitin)

(Pharmaceutical)

MEFOXIN® MSD Cefoxitin Sodium Antibiotic Action And Clinical Pharmacology: In vitro studies demonstrate that the bactericidal action of cefoxitin, a cephamycin derived from cephamycin C, results from the inhibition of bacterial cell wall synthesis. Evidence suggests that the methoxy group in the 7a position is responsible for the resistance of cefoxitin to degradation by bacterial beta-lactamases. Cefoxitin is poorly absorbed orally in humans. Cefoxitin, administered parenterally, produces high serum and…

Megral (Caffeine)

(Pharmaceutical)

MEGRAL® Glaxo Wellcome Ergotamine Tartrate – Cyclizine HCl – Caffeine Hydrate Migraine Therapy Indications And Clinical Uses: The treatment of vascular headache, migraine and related conditions where distention of cranial vessels appears to be the cause. Contra-Indications: Sepsis, occlusive vascular disease (thromboangiitis obliterans, luetic arteritis, severe arteriosclerosis, coronary artery disease, thrombophlebitis, Raynaud’s disease), thyrotoxicosis, anemia, renal or hepatic disease, hypertension, angina pectoris, peptic ulcer, infectious states, malnutrition, severe pruritus, pregnancy,…

Megace (Megestrol Acetate)

(Pharmaceutical)

MEGACE® MEGACE® OS Bristol Megestrol Acetate Antineoplastic – Progestogen – Antianorexic – Anticachectic Antianorexic – Anticachectic Action And Clinical Pharmacology: The precise mechanism of action by which megestrol produces its antineoplastic effects is unknown at present. Pharmacologic doses of megestrol exerted a direct cytotoxic effect on human breast cancer cells in vitro and proved capable of modifying and abolishing the stimulatory effects of estrogen on breast cancer cell lines. Megestrol…