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PREVACID® Abbott Lansoprazole H KATPase Inhibitor Note: When used in combination with antimicrobials for the eradication of H. pylori, the product monograph for those agents should be consulted. Action And Clinical Pharmacology: Lansoprazole inhibits the gastric H KATPase (the proton pump) which catalyzes the exchange of Hand K It is effective in the inhibition of both basal acid secretion and stimulated acid secretion. In healthy subjects, single and multiple doses…

PREPARATION H® CLEANSING PADS PREPARATION H® COOLING GEL PREPARATION H® CREAM PREPARATION H® OINTMENT PREPARATION H® SUPPOSITORIES Whitehall-Robins Hamamelis Water – Glycerin Phenylephrine HCI – Hamamelis Water Live Yeast Derivative (Bio-Dyne) – Shark Liver Oil Live Yeast Derivative (Bio-Dyne) – Shark Liver Oil Live Yeast Derivative (Bio-Dyne) – Shark Liver Oil Hemorrhoid Therapy – Anal Hygiene Hemorrhoidal Treatment Indications And Clinical Uses: Cleansing Pads: hemorrhoidal, toilet tissue irritation, anal cleansing…

PREPIDIL® GEL Pharmacia & Upjohn Dinoprostone Prostaglandin Action And Clinical Pharmacology: Dinoprostone gel, which contains a prostaglandin E2 analogue as the active ingredient, causes cervical ripening preparatory to the onset of labor when it is administered endocervically. Although the local effects of prostaglandin E2 on cervical maturation is not specifically known, experimental data indicates the drug enhances cervical hemodynamics which in turn promotes ripening of the cervix. Indications And Clinical…

PRESSYN® Ferring Vasopressin Antidiuretic Agent Action And Clinical Pharmacology: Vasopressin is a synthetic water-soluble pressor principle identical in sequence to lysine vasopressin. Vasopressin exerts its antidiuretic action by increasing the reabsorption of water by the renal tubules. The drug can also cause contraction of smooth muscle of the gastrointestinal tract and all parts of the vascular beds, especially the capillaries, small arterioles, and venules, with less effect on the smooth…

PRE-PEN® Rivex Pharma Benzylpenicilloyl-Polylysine Diagnostic – Penicillin Allergy Action And Clinical Pharmacology: The major antigenic determinant of penicillin hypersensitivity is the penicilloyl group, a degradation product of penicillin. Pre-Pen reacts specifically with penicilloyl skin sensitizing antibodies (reagins) to produce immediate wheal and flare reactions which may reflect increased risk of allergic reactions to subsequent penicillin therapy. Indications And Clinical Uses: As a skin test reagent for the detection of penicilloyl…

PREGNYL® Organon Chorionic Gonadotropin Gonadotropin Action And Clinical Pharmacology: Chorionic gonadotropin is a glycoprotein substance, with a molecular weight of approximately 38 600, secreted by the placenta and obtained from the urine of pregnant women. It is composed of nonidentical and noncovalently linked a and b subunits. The a subunit of CG is essentially identical to the a subunits of the human pituitary gonadotropins, luteinizing hormone and follicle-stimulating hormone, as…

PRANDASE® Bayer Acarbose Oral Antidiabetic Agent – Alpha-glucosidase Inhibitor Action And Clinical Pharmacology: Acarbose is a complex oligosaccharide that inhibits a-glucosidase activity in the brush border membrane of the small intestine. This delays the digestion of ingested carbohydrates, thereby resulting in a smoothing and lowering of blood glucose concentration following meals (postprandial). As a consequence of decreases in plasma glucose postprandial increases, acarbose reduces levels of glycosylated hemoglobin in patients…

PONSTAN® Parke-Davis Mefenamic Acid Analgesic Action And Clinical Pharmacology: Mefenamic acid, an anthranilic acid derivative, is a nonsteroidal anti-inflammatory drug (NSAID) with demonstrated anti-inflammatory, analgesic and antipyretic activity in laboratory animals. Its mode of action is not completely understood, but may be related to prostaglandin synthetase inhibition. In animal studies the drug was found to inhibit prostaglandin synthesis and to compete for binding at the prostaglandin receptor site. Pharmacokinetics: Mefenamic…

PONTOCAINE® Sanofi Tetracaine HCl Anesthetic Action And Clinical Pharmacology: Tetracaine is 2-(dimethylamino) ethyl p-(butylamino) benzoate monohydrochloride. It is a white crystalline odorless powder that is readily soluble in water, physiologic saline solution or dextrose solution. Tetracaine is a local anesthetic of the ester-linkage type, related to procaine. Tetracaine is detoxified by plasma esterases to para-aminobenzoic acid and diethylaminoethanol. tag_IndicationsIndications Indications And Clinical Uses: Where spinal anesthesia is indicated for operations…

PORTAGEN® Mead Johnson Therapeutic Nutrient Description: A nutritionally complete formulated liquid diet which contains medium chain triglycerides. Indications And Clinical Uses: For use in the nutritional management of individuals who do not efficiently digest and absorb conventional long chain food fats. For use in pancreatic insufficiency, bile acid deficiency, intestinal resection, lymphatic anomalies, steatorrhea. Precautions: The usual intake of water should be maintained when Portagen beverage is used as the…