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XYLOCAINE® CO2 Astra Lidocaine Hydrocarbonate Local Anesthetic Action And Clinical Pharmacology: Mechanism of Action: Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. Local anesthetics of the amide type are thought to act within sodium channels of the nerve membrane. Onset of Action: The onset of action with Xylocaine CO2 is faster than regular lidocaine HCl…

XANAX® XANAX TS Pharmacia & Upjohn Alprazolam Anxiolytic – Antipanic Action And Clinical Pharmacology: Alprazolam, a triazolo 1,4 benzodiazepine analog, binds with high affinity to the GABA benzodiazepine receptor complex. Considerable evidence suggest that the central pharmacologic/therapeutic actions of alprazolam are mediated via interaction with this receptor complex. Pharmacokinetics: Orally administered alprazolam is readily absorbed in man. Plasma levels are proportional to the dose given; over the dose range of…

XYLOCAINE® DENTAL SOLUTIONS Astra Lidocaine HCl – Epinephrine Local Anesthetic Action And Clinical Pharmacology: Mechanism of Action: Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. Local anesthetics of the amide type are thought to act within sodium channels of the nerve membrane. Onset of Action: When used for infiltration anesthesia in dental patients, the onset…

XYLOCAINE® ENDOTRACHEAL Astra Lidocaine HCl Topical Anesthetic Action And Clinical Pharmacology: Mechanism of Action: Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. Local anesthetics of the amide type are thought to act within the sodium channels of the nerve membrane. Onset of Action: Lidocaine, when applied topically to the oral cavity, acts on mucous membranes…

WESTCORT® Preparations Westwood-Squibb Hydrocortisone-17-valerate Topical Corticosteroid Action And Clinical Pharmacology: Studies conducted in healthy adult volunteers illustrated that 0.2% Hydrocortisone-17-valerate cream and ointment has minimal primary irritant and contact sensitization potential. Adrenal suppression studies with the cream indicated that any observed reduction in pituitary-adrenal function was rapidly reversible. Indications And Clinical Uses: Topical therapy of acute and chronic corticosteroid responsive dermatoses, where an anti-inflammatory, anti-allergenic and antipruritic activity is required…

WinRho SDF™ Cangene Rho (D) Immune Globulin (Human) Passive Immunizing Agent Action And Clinical Pharmacology: Rho (D) Immune Globulin (Human) is a sterile freeze-dried gamma globulin (IgG) fraction of human plasma containing antibodies to Rho (D), prepared by an anion-exchange column chromatography method. The incorporation of the Solvent Detergent step, which includes treatment with Tri-n-butyl phosphate and Triton X-100, in the WinRho SDF process is designed to increase the safety…

X-PREP® Purdue Frederick Standardized Sennosides Diagnostic Aid Indications And Clinical Uses: A potent cathartic to be used only for evacuation of the colon prior to contrast radiography of the gastrointestinal tract, other abdominal radiography, or examinations where a clear colon is essential for proper visualization. Also indicated prior to surgery of the colon or rectum. Contra-Indications: The “acute abdomen”. Dosage And Administration: Adults: At 10 a.m. on the day prior…

XALATAN™ Pharmacia & Upjohn Latanoprost Prostaglandin F2  Analogue Action And Clinical Pharmacology: Latanoprost, a novel prostaglandin F2  analogue, is a selective prostanoid FP receptor agonist which reduces the intraocular pressure by increasing the outflow of aqueous humor. Studies in animals and man indicate that the main mechanism of action is increased uveoscleral outflow. Primary open-angle glaucoma is a disease with characteristic optic nerve damage and a corresponding visual field defect….

WEBBER® VITAMIN E OINTMENT Novartis Consumer Health d-Alpha Tocopheryl Acetate Emollient Action And Clinical Pharmacology: Vitamin E functions as an antioxidant and stabilizer of cell membranes. Indications And Clinical Uses: For the treatment of sunburn, minor cuts and burns and other minor skin irritations. Precautions: If adverse reaction or irritation occurs, discontinue use and consult a physician. In the case of a serious burn, consult a physician. Not for ophthalmic…

WELLFERON® Glaxo Wellcome Interferon alpha-n1 (Ins) Biological Response Modifier Action And Clinical Pharmacology: Wellferon is a highly purified blend of natural human alpha interferons, obtained from human lymphoblastoid cells following induction with Sendai virus. Wellferon resembles human leukocyte interferon in that it is a mixture of natural alpha subtypes but differs in that these are present in different proportions. It also differs from recombinant alpha interferon preparations made from bacteria…