You searched for : 'Q'

ZEPHIRAN® Sanofi Benzalkonium Chloride Topical Antiseptic Indications And Clinical Uses: Antisepsis of skin and mucous membranes and as a disinfectant in surgery, obstetrics and gynecology, urology, ophthalmology, otorhinolaryngology and general practice. Also may be used as a disinfectant for hospital utensils and other environmental surfaces and for disinfection and storage of ampuls, thermometers, metal instruments and catheters. Contra-Indications: Incompatible with soap and anionic detergents. Use in occlusive dressings, casts and…

ZANTAC® Glaxo Wellcome Ranitidine HCl Histamine H2 Receptor Antagonist Action And Clinical Pharmacology: Ranitidine is an antagonist of histamine at gastric H2 receptor sites. Thus ranitidine inhibits both basal gastric secretion and gastric acid secretion induced by histamine, pentagastrin and other secretagogues. On a weight basis, ranitidine is between 4 and 9 times more potent than cimetidine. Inhibition of gastric acid secretion has been observed following i.v., intraduodenal and oral…

ZARONTIN® Parke-Davis Ethosuximide Anticonvulsant Indications And Clinical Uses: The control of absence (petit mal) epilepsy. Contra-Indications: Ethosuximide should not be used in patients with a history of hypersensitivity to succinimides. Precautions: Blood dyscrasias, including some with fatal outcome, have been reported to be associated with the use of ethosuximide; therefore, periodic blood counts should be performed. Ethosuximide is capable of producing morphological and functional changes in the animal liver. In…

ZEMURON™ Organon Rocuronium Bromide Nondepolarizing Skeletal Neuromuscular Blocking Agent Action And Clinical Pharmacology: Rocuronium is a nondepolarizing neuromuscular blocking agent with a rapid to intermediate onset depending on dose and an intermediate duration of action. The drug acts by binding competitively to cholinergic receptors at the motor end-plate to antagonize the action of acetylcholine, an effect which is reversible in the presence of acetylcholinesterase inhibitors, such as neostigmine and edrophonium….

ZAROXOLYN® Rhône-Poulenc Rorer Metolazone Diuretic – Antihypertensive Action And Clinical Pharmacology: Metolazone is a quinazoline diuretic/antihypertensive agent. The action of metolazone is to interfere with the renal tubular mechanism of electrolyte reabsorption. The mechanism of this action is unknown. Metolazone acts primarily to inhibit sodium reabsorption at the cortical diluting site and in the proximal convoluted tubule. Sodium and chloride ions are excreted in approximately equivalent amounts. The increased delivery…

Z-BEC® Whitehall-Robins Zinc – Multivitamins Indications And Clinical Uses: For deficiencies of Z-BEC’s components in conditions such as febrile diseases, chronic or acute infections, burns, fractures, surgery, leg ulcers, toxic conditions, physiologic stress, alcoholism, prolonged exposure to high temperature, geriatrics, gastritis, peptic ulcer and colitis; in conditions involving special diets and weight reduction diets; dentistry: herpetic stomatitis, aphthous stomatitis, cheilosis, herpangina and gingivitis. Precautions: Not intended for the treatment of…

ZADITEN® Novartis Ketotifen Fumarate Pediatric Asthma Prophylactic – Antiallergic Agent Action And Clinical Pharmacology: Ketotifen is a nonbronchodilator antiasthmatic drug which inhibits the effects of certain endogenous substances known to be inflammatory mediators, and thereby exerts antiallergic activity. Preclinical studies indicated that ketotifen’s anti-H1 effect seems to be distinct from its antiallergic properties. The effectiveness of ketotifen in the chronic management of mild atopic pediatric asthma has been shown in…

ZANOSAR® Pharmacia & Upjohn Streptozocin Antineoplastic Agent Action And Clinical Pharmacology: Streptozocin inhibits DNA synthesis in bacterial and mammalian cells. In bacterial cells, a specific interaction with cytosine moieties leads to degradation of DNA. The biochemical mechanism leading to mammalian cell death has not been definitively established; levels required to kill cells are considerably lower than those required to inhibit DNA synthesis or several of the enzymes involved in DNA…

ZANTAC® 75 Glaxo Wellcome Ranitidine HCl Histamine H2-receptor Antagonist Action And Clinical Pharmacology: Ranitidine is an antagonist of histamine at gastric H2-receptor sites. Thus, ranitidine inhibits both basal gastric secretion and gastric acid secretion induced by histamine, pentagastrin and other secretagogues. Inhibition of gastric acid secretion has been observed following i.v., intraduodenal and oral administration of ranitidine. This response is dose-related, a maximum response being achieved at an oral dose…

YUTOPAR® Bristol Ritodrine HCl Uterine Relaxing Agent Action And Clinical Pharmacology: Ritodrine is a beta-receptor agonist, which has been shown by in vitro and vivo pharmacologic studies in animals to exert a preferential effect on the adrenergic receptors such as those in the uterine smooth muscle. Stimulation of the receptors inhibits contractility of the uterine smooth muscle. Beta-adrenergic stimulation in other body systems may lead to some cardiovascular or metabolic…