X-Prep

Medically reviewed by . Last updated on May 6, 2023

X-PREP®

Purdue Frederick

Standardized Sennosides

Diagnostic Aid

Indications And Clinical Uses: A potent cathartic to be used only for evacuation of the colon prior to contrast radiography of the gastrointestinal tract, other abdominal radiography, or examinations where a clear colon is essential for proper visualization. Also indicated prior to surgery of the colon or rectum.

Contra-Indications: The “acute abdomen”.

Dosage And Administration: Adults: At 10 a.m. on the day prior to x-ray procedure, drink 50% the contents of a 21 g pouch of the powder mixed with water, or 50% the contents of a 70 mL bottle of the liquid, and the remaining 50% at 2 p.m., or as prescribed. As it is important to hydrate the patient, adults should take several glasses of water within 3 to 4 hours of completing dosage.

Children: Dosage (on a weight basis) is proportionally less.

Availability And Storage: Liquid: Each unit dose (70 mL) bottle contains: standardized sennosides 119 mg, sugar 46.8 g equivalent to 872 kJ (212 kcal). Also contains alcohol 7%, parabens 154 mg and artificial cocoa flavor. pH: 5.2 to 5.8. Expiration period: 2 years from date of manufacture. Tartrazine-free. Cases of 50.

Powder: Each unit dose (21 g) pouch contains: standardized sennosides 157.5 mg. Also contains sugar 9.5 g equivalent to 160 kJ (38 kcal) and cocoa powder. Tartrazine-free. Cases of 50.

X-PREP® Purdue Frederick Standardized Sennosides Diagnostic Aid


About

Holly McCain, PharmD is a long-term care pharmacist licensed in multiple states, specializing in skilled nursing, assisted living, ICF/IDD, and medical-at-home services. She has over six years of pharmacy management experience, leading regulatory inspections, supervising multidisciplinary teams, and overseeing sterile IV compounding and pharmacy automation. Her expertise spans Medicare and Medicaid compliance, medication safety, and operational alignment in senior care settings. Holly is an active member of ASCP, AMCP, ASHP, and the Senior Care Pharmacy Coalition.

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