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EUGLUCON® Pharmascience Glyburide Oral Hypoglycemic Indications And Clinical Uses: To control hyperglycemia in glyburide responsive diabetes mellitus of stable, mild, nonketosis prone, maturity-onset or adult type which cannot be controlled by proper dietary management and exercise, or when insulin therapy is not appropriate. Contra-Indications: Known hypersensitivity or allergy to glyburide; unstable and/or insulin-dependent diabetes mellitus; ketoacidosis; coma; stress conditions such as severe infections, trauma or surgery; the presence of jaundice,…

EURAX® Novartis Consumer Health Crotamiton Antipruritic Indications And Clinical Uses: To relieve itching in most types of dermatosis, notably: atopic dermatitis, chickenpox, contact dermatitis, creeping eruption, dermatitis herpetiformis, dermatitis medicamentosa, dermatophytosis, eczema, insect bites, intertrigo, lichen planus, neurodermatitis, neurotic excoriation, pityriasis rosea, poison ivy dermatitis, pruritus ani, scroti and vulvae, psoriasis, seborrheic dermatitis, senile pruritus, sunburn, urticaria, varicose eczema. Contra-Indications: Acutely inflamed skin or raw, weeping areas. Hypersensitivity to crotamiton….

ETRAFON® Preparations Schering Amitriptyline HCl – Perphenazine Antidepressant – Antipsychotic Indications And Clinical Uses: The treatment of patients with anxious or agitated depression. Particularly indicated in patients with depression associated with marked psychomotor unrest and anxiety. Etrafon has also been used in some schizophrenic patients who have associated symptoms of depression and in depressed patients suffering from marked agitation, anxiety and tension, which may respond to a phenothiazine agent. Contraindications,…

EUFLEX® Schering Flutamide Nonsteroidal Antiandrogen Action And Clinical Pharmacology: Flutamide demonstrates potent antiandrogenic effects by inhibiting androgen uptake and/or inhibiting nuclear binding of androgen in target tissues. In adult male rats, ventral prostate weights and seminal vesicle weights were markedly reduced by daily administration of flutamide. Indications And Clinical Uses: For use in combination with LHRH agonistic analogues (such as leuprolide acetate) for the treatment of metastatic prostatic carcinoma (Stage…

ETHAMBUTOL HCl General Monograph Antimycobacterial Pharmacology: Ethambutol is a bacteriostatic agent which diffuses into actively growing mycobacterium cells such as tubercle bacilli, where it inhibits the synthesis of one or more essential metabolites, causing impairment of cell metabolism, arrest of multiplication, and cell death. It is active in vitro against strains of M. tuberculosis and other Mycobacterium species, but not other bacteria, fungi or viruses. Resistance develops rapidly if ethambutol…

ETHRANE® Zeneca Enflurane  Inhalation Anesthetic Action And Clinical Pharmacology: Enflurane is an inhalation anesthetic. Induction and recovery from anesthesia with enflurane are rapid. Enflurane does not appear to stimulate excessive salivation or tracheabronchial secretions, or affect bronchomotor tone. Pharyngeal and laryngeal reflexes are readily obtunded. The level of anesthesia changes rapidly, which would be predicted based upon its Oswald partition coefficients. Enflurane reduces ventilation as depth of anesthesia increases. This…

ETHYOL® Lilly Amifostine Cytoprotective Agent Action And Clinical Pharmacology: Amifostine is a prodrug that is dephosphorylated to a pharmacologically active metabolite, the free thiol (WR-1065), at the tissue site by membrane-bound alkaline phosphatase. The ability of amifostine to selectively protect normal tissues is based upon the differential metabolism and uptake of the free thiol into normal versus malignant tissues. This differential effect is attributed to the higher capillary alkaline phosphatase…

ETOPOSIDE INJECTION Novopharm Antineoplastic Action And Clinical Pharmacology: Etoposide is a semisynthetic derivative of podophyllotoxin. Etoposide exhibits cytostatic activity in vitro by preventing cells from entering mitosis or by destroying them at a premitotic stage. Etoposide interferes with the synthesis of DNA and appears to arrest human lymphoblastic cells in the late S-G2 phases of the cell cycle. The effects of etoposide on the human hematopoietic system are substantial. The…

ESTRACOMB® Novartis Pharmaceuticals Estradiol-17b – Norethindrone Acetate – Estradiol-17b Estrogen – Progestin Action And Clinical Pharmacology: Estracomb is designed to provide continuous estrogen and sequential progestin therapy, in a 28-day treatment cycle, for women with an intact uterus. Estracomb contains 2 types of transdermal therapeutic systems, Estraderm 50 (10 cm and Estragest 250/50 (20 cm. Estraderm 50 contains estradiol-17b and Estragest 250/50 contains norethindrone acetate (NETA) and estradiol-17b, respectively. Both…

ESTRACE® Roberts Estradiol-17b (micronized) Estrogen Action And Clinical Pharmacology: Estrogens are secreted mainly by the gonads and, to a very small amount, by the adrenals. In addition, they are formed, to an important degree, from peripheral conversion of adrenal and gonadal androgens to estrogens. They circulate in both unconjugated and conjugated forms in the blood, with the unconjugated estrogens, either free or bound to proteins, mainly albumin, or to the…