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FER-IN-SOL® Mead Johnson Ferrous Sulfate Hematinic Indications And Clinical Uses: Prevention and treatment of iron deficiency anemia. Contra-Indications: Hemosiderosis, hemochromatosis, hemolytic anemia. Precautions: Oral iron preparations may aggravate existing peptic ulcer, regional enteritis and ulcerative colitis. Iron compounds taken orally can impair the absorption of tetracycline antibiotics. Antacids given concomitantly with iron compounds decrease iron absorption. When iron drops are given to babies some darkening of the gum tissue directly…

FERMALAC® Rougier Lactobacillus Acidophilus Compound Flora Modifier Indications And Clinical Uses: The treatment of mild diarrhea and intestinal upset, particularly when associated with antibiotic therapy. Precautions: Store under refrigeration. Should not be used to prepare yogurt or acidophilus milk. Dosage: Adults: 1 to 2 capsules 3 times/day. Availability And Storage: Each No. 0 enteric coated capsule with opaque blue top and opaque white bottom contains: 1 billion fully viable bacilli…

FANSIDAR® Roche Sulfadoxine – Pyrimethamine Antimalarial Action And Clinical Pharmacology: Fansidar is a combination of sulfadoxine and pyrimethamine, which inhibits sequential steps involved in the biosynthesis of tetrahydrofolic acid. This depletes folic acid, an essential cofactor in the biosynthesis of nucleic acids, resulting in interference with protozoal nucleic acid and protein production. Sulfadoxine is a structural analogue of para-aminobenzoic acid (PABA) and competitively inhibits the enzyme dihydropteroate synthetase. Pyrimethamine is…

FASTIN® SmithKline Beecham Phentermine HCl Anorexiant Action And Clinical Pharmacology: Phentermine is a sympathomimetic amine with pharmacologic activity similar to the prototype drugs of this class used in obesity, the amphetamines. Actions include CNS stimulation and elevation of blood pressure. Tachyphylaxis and tolerance have been demonstrated with all drugs of this class in which these phenomena have been looked for. Drugs of this class used in obesity are commonly known…

FEIBA® VH IMMUNO Baxter Human Plasma Factor VIII Inhibitor Coagulant Complex Anti-inhibitor Description: Feiba VH Immuno, is a freeze-dried sterile human plasma fraction with Factor VIII inhibitor bypassing activity. In vitro, Feiba VH Immuno shortens the activated partial thromboplastin time (APTT) of plasma containing Factor VIII inhibitor. Factor VIII inhibitor bypassing activity is expressed in arbitrary units. One Immuno Unit of activity is defined as that amount of Feiba VH…

EX-LAX® Chocolated Pieces EX-LAX® Sugar Coated Pills EX-LAX® Extra Strength Sugar Coated Pills Novartis Consumer Health Sennosides Laxative Action And Clinical Pharmacology: Sennosides are a natural source complex of anthraquinone glycosides found in senna. They exert a stimulant laxative effect that increases peristalsis by direct action on the smooth muscle of the intestine. They generally produce bowel movement in 6 to 12 hours. Indications And Clinical Uses: For the overnight…

EVISTA™ Lilly Raloxifene HCl Selective Estrogen Receptor Modulator Action And Clinical Pharmacology: Raloxifene is a selective estrogen receptor modulator (SERM) that belongs to the benzothiophene class of compounds. The SERM profile of raloxifene includes estrogen agonist effects on bone and lipid metabolism but not in uterine or breast tissues. Pharmacokinetics: The disposition of raloxifene has been evaluated in 276 postmenopausal women in conventional clinical pharmacology studies and in more than…

EXOSURF® NEONATAL Glaxo Wellcome Colfosceril Palmitate Synthetic Lung Surfactant Action And Clinical Pharmacology: Surfactant deficiency is an important factor in the development of the neonatal respiratory distress syndrome (RDS). Natural surfactant, a combination of lipids and apoproteins, exhibits not only surface tension reducing properties (conferred by the lipids), but also rapid spreading and adsorption (conferred by the apoproteins). The major fraction of the lipid component of natural surfactant is colfosceril…

FAMVIR™ SmithKline Beecham Famciclovir Antiviral Agent Action And Clinical Pharmacology: Famciclovir is the orally administered pro-drug of the antiviral agent penciclovir. Famciclovir itself has no antiviral activity until it is biotransformed to penciclovir. Following oral administration little or no famciclovir is detected in plasma or urine since famciclovir is rapidly converted via deacetylation and oxidation to penciclovir. Studies in volunteers have shown that famciclovir is well absorbed and produces plasma…

EUMOVATE® Glaxo Wellcome Clobetasone 17-butyrate Topical Corticosteroid Action And Clinical Pharmacology: The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects. Topical corticosteroids such as clobetasone are effective in the treatment of corticosteroid-responsive dermatoses primarily because of their anti-inflammatory, anti-puritic, and vasoconstrictive actions. However while the physiologic, pharmacologic…