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BENADRYL® Preparations Warner-Lambert Consumer Healthcare Diphenhydramine HCl Antihistaminic Indications And Clinical Uses: Antihistamine, antiemetic and antispasmodic. Allergic diseases such as hay fever, allergic rhinitis, urticaria, angioedema, atopic dermatitis, contact dermatitis, gastrointestinal allergy, pruritus, physical allergies, reactions to injection of contrast media, reactions to therapeutic preparations and allergic transfusion reactions; also postoperative nausea and vomiting, motion sickness, and quieting emotionally disturbed children. Contra-Indications: Cream should not be applied to extensively denuded…

BENADRYL® ALLERGY/SINUS/HEADACHE Warner-Lambert Consumer Healthcare Diphenhydramine HCl – Pseudoephedrine HCl – Acetaminophen Antihistaminic – Decongestant – Analgesic Indications And Clinical Uses: For relief of sneezing, runny nose, itchy watery eyes, sinus and nasal congestion, sinus pain and headache. Precautions: Occupational Hazards: May cause drowsiness, use caution when driving a motor vehicle or operating machinery. A physician should be consulted prior to using this product if patient has chronic alcoholism, serious…

BCG Vaccine (Freeze Dried) Connaught Attenuated Tubercle Bacillus Active Immunizing Agent Action And Clinical Pharmacology: BCG Vaccine (Freeze-Dried) for intracutaneous administration, as prepared by Connaught Laboratories Limited, is made from a culture of an attenuated strain of living bovine tubercle bacillus (Bacillus Calmette-Gurin). It is supplied as a freeze-dried product ready for immediate use following reconstitution with the accompanying diluent, which consists of sterile phosphate-buffered saline. The manufacturing and testing…

BACITRACIN Pharmacia & Upjohn Antibiotic Action And Clinical Pharmacology: Bacitracin, an antibiotic substance derived from cultures of B. subtilis (Tracey), exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy. Bacitracin is assayed against a standard and its activity is expressed in units, 1 mg having a potency of not less…

BACIGUENT® Johnson & Johnson• Merck Bacitracin Topical Antibiotic Indications And Clinical Uses: For the treatment and prevention of infection in minor cuts, wounds and burns. Manufacturers’ Warnings In Clinical States: For external use only. Avoid contact with eyes. If contact occurs, wash thoroughly with water. Use should be discontinued if condition worsens. No refrigeration required. Precautions: Discontinue if sensitization occurs. Prolonged use may result in the overgrowth of nonsusceptible organisms,…

ARLIDIN® ARLIDIN® FORTE Rhône-Poulenc Rorer Nylidrin HCl Peripheral Vasodilator – Organic Brain Syndrome Therapy Action And Clinical Pharmacology: Nylidrin acts predominantly by beta receptor stimulation. It has been shown to dilate arterioles in skeletal muscle and to increase cardiac output. An increase in cerebral blood flow and a decrease in vascular resistance has also been reported. The result of this combination of actions is a greater blood supply to ischemic…

ANTIVERT™ Pfizer Meclizine HCl – Nicotinic Acid Vertigo Therapy Action And Clinical Pharmacology: Meclizine has antihistaminic and anticholinergic properties. Nicotinic acid is a vasodilator agent which has been found effective in the treatment of vertigo due to cerebral arteriosclerosis. The site and mechanism of action of meclizine in controlling vertigo arising from various conditions, have not been clearly defined. Pharmacological studies conducted with other antihistamines show that the peripheral labyrinthine…

ANTABUSE® Wyeth-Ayerst Disulfiram Alcohol Deterrent Action And Clinical Pharmacology: Disulfiram produces a sensitivity to alcohol which results in a highly unpleasant reaction when the patient under treatment ingests even small amounts of alcohol. Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage. During alcohol metabolism after disulfiram intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of…

ANEXATE® Roche Flumazenil Benzodiazepine Antagonist Action And Clinical Pharmacology: Flumazenil, an imidazobenzodiazepine, is a benzodiazepine antagonist which blocks the central effects of agents that act via the benzodiazepine receptor, by competitive inhibition. The antagonism is specific, since in animal experiments the effects of compounds which have no affinity for the benzodiazepine receptor (e.g., barbiturates, meprobamate, ethanol, GABA-mimetics, and adenosine receptor agonists) were not affected by flumazenil. Following the i.v. administration…

ANACIN® ANACIN® EXTRA STRENGTH Whitehall-Robins ASA – Caffeine Analgesic – Antipyretic – Anti-inflammatory Indications And Clinical Uses: For fast relief of headaches, aches and fever of colds, arthritic and rheumatic pain, toothache and menstrual pain. Contra-Indications: Sensitivity to salicylates, bleeding ulcers and patients with blood coagulation defects, hemophilia, anemia, vitamin K deficiency, renal function impairment, asthma, sensitivity to caffeine and cardiac disease. Manufacturers’ Warnings In Clinical States: All salicylates should…