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NILSTAT® Technilab Nystatin Antifungal Antibiotic Indications And Clinical Uses: Oral Drops: Monilial infections of the mouth (thrush) and intestinal moniliasis in infants and children. Oral Tablets: Prevention and treatment of intestinal moniliasis. Prevention or treatment of lower intestinal and anal infections caused by Candida albicans (monilia). Powder: For the treatment of infections of the oral cavity by C. albicans (monilia). Cream and Ointment: Treatment of cutaneous or mucocutaneous mycotic infections…

NIMBEX® Glaxo Wellcome Cisatracurium Besylate Nondepolarizing Skeletal Neuromuscular Blocking Agent Action And Clinical Pharmacology: Cisatracurium is an intermediate-acting, nondepolarizing neuromuscular blocking agent for i.v. administration. Cisatracurium, 1 of 10 isomers of atracurium besylate, constitutes approximately 15% of that mixture. Cisatracurium binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in block of neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as…

NEULEPTIL® Rhône-Poulenc Rorer Pericyazine Psychotropic Agent Action And Clinical Pharmacology: Pericyazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine effects, and an action on the extrapyramidal system. Like other…

NegGram® Sanofi Nalidixic Acid Urinary Antibacterial Action And Clinical Pharmacology: Nalidixic acid has bactericidal activity against gram-negative rods such as Escherichia, Klebsiella, Aerobacter and Proteus. It is relatively inactive against gram-positive bacteria. The mode of action is believed to be interference with the replication of genetic information by the blocking of the synthesis of bacterial DNA. Bacterial cross-resistance between nalidixic acid and other quinolone antimicrobials has been observed only with…

NARDIL® Parke-Davis Phenelzine Sulfate Antidepressant Action And Clinical Pharmacology: Phenelzine is a potent monoamine oxidase (MAO) inhibitor. Monoamine oxidase is a complex enzyme system, widely distributed throughout the body. Drugs that inhibit monoamine oxidase in the laboratory are associated with a number of clinical effects. Thus, it is unknown whether MAO inhibition per se, other pharmacologic actions, or an interaction of both is responsible for the clinical effects observed. All…

MUMPSVAX® MSD Mumps Virus Vaccine, Live, Attenuated Mumps Prophylaxis Description: This vaccine is prepared from the Jeryl Lynn (B Level) strain, named after the patient from whom the virus was initially recovered. Mumpsvax is a sterile lyophilized preparation of the Jeryl Lynn (B level) strain of mumps virus. The virus was adapted to and propagated in cell cultures of chick embryo, free of avian leukosis, virus and other adventitious agents…

MSD® ENTERIC COATED ASA Johnson & Johnson Merck ASA Nonsteroidal Anti-inflammatory – Analgesic – Platelet Aggregation Inhibitor Action And Clinical Pharmacology: ASA has analgesic, antipyretic and anti-inflammatory properties. In rheumatic diseases, although the analgesic and antipyretic effects are useful, the major purpose for which ASA is used is to reduce the intensity of the inflammatory process. Inhibition of prostaglandin synthesis may be involved in the anti-inflammatory action of ASA. ASA…

MEXITIL® Boehringer Ingelheim Mexiletine HCl Antiarrhythmic Action And Clinical Pharmacology: Mexiletine is a class 1B antiarrhythmic agent based on the classification system of Vaughan-Williams with local anesthetic properties, similar in structure and activity to lidocaine. Mexiletine blocks the fast sodium channel in cardiac tissues, especially the Purkinje network, without involvement of the autonomic system. Mexiletine reduces the rate of rise and amplitude of the action potential and decreases automaticity (increases…

METAMUCIL® Preparations Procter & Gamble Psyllium Hydrophilic Mucilloid Laxative – Fibre Supplement Indications And Clinical Uses: The relief of chronic, atonic, spastic and rectal constipation and for the constipation accompanying pregnancy, convalescence and advanced age. As adjunctive therapy in the constipation of mucous and ulcerative colitis and diverticulitis. To provide supplementary dietary fibre in special dietary programs. Also useful in the management of hemorrhoids and following anorectal surgery. Contra-Indications: Presence…

MERITENE® Novartis Nutrition Therapeutic Nutrient Indications And Clinical Uses: As a supplement or as a tube feeding, recommended whenever protein needs are increased and energy requirements are moderate. Meritene Powder provides 18 g protein and 275 kcal (1 150 kJ)/serving. Precautions: Not for parenteral use. Dosage And Administration: Oral: As a supplement with or between meals: 1 to 3 servings daily, 1 150 to 3 450 kJ (275 to 825…