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ROBINUL® ROBINUL® FORTE Wyeth-Ayerst Glycopyrrolate Anticholinergic Indications And Clinical Uses: The management of gastrointestinal disorders amenable to anticholinergic therapy, such as: duodenal ulcer, duodenitis, pylorospasm; gastric ulcer, gastritis, hiatal hernia, hyperchlorhydria, pyrosis, aerophagia, gastroenteritis; esophagitis; cholecystitis, chronic pancreatitis; spastic and irritable colon, ulcerative colitis, functional bowel distress, diverticulitis, acute enteritis, diarrhea; and splenic flexure syndrome, neurogenic gastrointestinal disturbances. Contra-Indications: Glaucoma, urinary bladder neck obstruction, pyloric obstruction, stenosis with significant gastric…

Introduction Robitussin (guaifenesin) is an expectorant. It helps reduce congestion in your chest and throat, making it easier for you to cough out through your mouth. Here’s everything you need to know, including how it works, as well as uses, contraindications, side effects, interactions, storage and precautions. Action And Clinical Pharmacology Guaifenesin enhances the output of lower respiratory tract fluid. The enhanced flow of less viscid secretions promotes ciliary action, and…

ROCEPHIN® Roche Ceftriaxone Sodium Antibiotic Action And Clinical Pharmacology: In vitro studies indicate that the bactericidal action of ceftriaxone results from the inhibition of cell-wall synthesis. In E. coli, ceftriaxone showed a high affinity for penicillin binding proteins (PBP) 1a and 3 and a moderate affinity for 1b and 2. In H. influenzae, the highest affinity was shown for PBP 4 and PBP 5. The binding affinity to PBP 4…

ROCALTROL® Roche Calcitriol Vitamin D3 Metabolite Action And Clinical Pharmacology: The supply of vitamin D in man depends on dietary intake and/or exposure to the ultraviolet rays of the sun for conversion of 7-dehydrocholesterol to vitamin D3 (cholecalciferol). Vitamin D3 (cholecalciferol) must be metabolized in the liver and the kidneys before it is fully active on its target tissues. The initial transformation is catalyzed by a vitamin D3-25-hydroxylase enzyme (25-OH-ase)…

ROBAXIN® ROBAXIN®-750 Whitehall-Robins Methocarbamol Skeletal Muscle Relaxant Action And Clinical Pharmacology: The mechanism of action of methocarbamol has not been established, but may be due to general CNS depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber. Methocarbamol is metabolized to yield a dealkylated and a hydroxylated product. These 2 metabolites are found primarily as glucuronide and sulfate…

Introduction Robaxacet is an adult medication used to treat muscle spasms and pain. It helps to relax the muscles and decrease the pain. Its effects can be felt within 1 hour. Action And Clinical Pharmacology This product provides a dual approach to the management of discomforts associated with musculoskeletal disorders. The mechanism of action of methocarbamol has not been established, but may be due to general CNS depression. It has no…

ROBAXISAL®-C Whitehall-Robins Methocarbamol – ASA – Codeine Phosphate Skeletal Muscle Relaxant – Analgesic Action And Clinical Pharmacology: The mechanism of action of methocarbamol has not been established, but may be due to general CNS depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fibre. Methocarbamol is metabolized to yield a dealkylated and a hydroxylated product. These 2 metabolites are…

ROBAXISAL® ROBAXISAL® EXTRA STRENGTH Whitehall-Robins Methocarbamol – ASA Skeletal Muscle Relaxant – Analgesic Action And Clinical Pharmacology: The mechanism of action of methocarbamol has not been established, but may be due to general CNS depression. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fibre. Methocarbamol is metabolized to yield a dealkylated and a hydroxylated product. These 2 metabolites are…

ROBINUL® INJECTABLE Wyeth-Ayerst Glycopyrrolate Anticholinergic Action And Clinical Pharmacology: Glycopyrrolate, like other anticholinergic (antimuscarinic) agents, competitively antagonizes the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. Glycopyrrolate antagonizes muscarinic symptoms (e.g., bronchorrhea, bronchospasm, bradycardia and intestinal hypermotility) induced by cholinergic drugs such as the anticholinesterases. As a premedicant, glycopyrrolate injectable reduces excessive pharyngeal, tracheal and bronchial…

R & C™ Shampoo/Conditioner R & C Pyrethrins – Piperonyl Butoxide Pediculicide – Ovicide Indications And Clinical Uses: For the treatment of infestations with head lice (P. capitis), body lice (P. corporis), crab lice (P. pubis) and their nits. Contra-Indications: Should not be used by persons allergic to chrysanthemum, pyrethrin or synthetic pyrethroids. Precautions: For external use only. Harmful if swallowed. It should not be inhaled. During shampooing, contact should…