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SUPLASYN® Paladin Sodium Hyaluronate Synovial Fluid Replacement Action and Clinical Hyaluronic acid is a naturally occurring mucopolysaccharide present in the connective tissue of all animals. It is a biological polymer composed of repeating units of two sugars, D-glucuronic acid and N-acetylglycosamine, linked by glycosidic bonds. This configuration for hyaluronic acid is the same for all living species from bacteria to man. High concentrations are found in synovial fluid, the vitreous…

SUPRAX® Rhône-Poulenc Rorer Cefixime Antibiotic Action and Clinical Pharmacology: Cefixime exerts its bactericidal effect by attaching to penicillin-binding proteins and inhibiting peptidoglycan synthesis, thus causing damage to the bacterial cell wall.: Pharmacokinetics: Following oral dosing, cefixime attains peak serum levels in approximately 4 hours. The half-life is about 3 to 4 hours and is not dose dependent. Cefixime is excreted by renal and biliary mechanisms. About 50% of the absorbed dose is excreted…

SUPRANE® AstraZeneca Desflurane Inhalation Anesthetic Action and Clinical Pharmacology: Desflurane is a volatile inhalational anesthetic whose low solubility (blood/gas partition coefficient equals 0.42) permits rapid variation in anesthetic depth. If anesthesia is maintained with inflow rates of greater than 2 L/min, the alveolar concentration is usually within 10% of the inspired concentration. It is not necessary to deliver concentrations of desflurane far in excess of the desired end-tidal concentration (“overpressurization”…

SULCRATE® SUSPENSION PLUS Hoechst Marion Roussel Sucralfate Gastroduodenal Cytoprotective Agent Action and Clinical Pharmacology: Sucralfate exerts a generalized gastric cytoprotective effect by enhancing natural mucosal defense mechanisms. Studies conducted in animals and clinical trials in humans have demonstrated that sucralfate can protect the gastric mucosa against various irritants such as alcohol, ASA, hydrochloric acid, sodium hydroxide or sodium taurocholate. In addition, sucralfate has been demonstrated to have a greater affinity…

SULFACET-R® Dermik Sulfacetamide Sodium-Sulfur Acne Therapy Indications And Clinical Uses: Severe acne vulgaris, seborrheic dermatitis, bacterial folliculitis and related conditions. Contra-Indications: Hypersensitivity to the sulfonamides as indicated by a previous toxic reaction to them (e.g. agranulocytosis, acute hemolytic anemia, purpura hemorrhagica, drug fever, jaundice, or contact dermatitis). Precautions: Sulfur may cause reddening and scaling of the epidermis, but if undue skin irritation develops or increases, discontinue use and consult a…

SUCCINYLCHOLINE CHLORIDE INJECTION USP Bioniche Neuromuscular Blocking Agent Availability And Storage: Each mL of sterile solution contains: succinylcholine chloride (anhydrous base) 20 mg equivalent to dihydrate 22 mg. Nonmedicinal ingredients: hydrochloric acid (to adjust pH) and sodium chloride (for isotonicity). Ampuls of 5 mL, boxes of 10. Multiple dose vials of 10 and 20 mL (also contains methylparaben and propylparaben), trays of 10. Refrigerate (2 to 8°C) to prevent a…

SUDAFED® COLD & COUGH EXTRA STRENGTH, SUDAFED® COLD & FLU, SUDAFED® DECONGESTANT, SUDAFED® DECONGESTANT EXTRA STRENGTH, SUDAFED® DECONGESTANT 12 HOUR, SUDAFED® DECONGESTANT CHILDREN’S CHEWABLE, SUDAFED® HEAD COLD AND SINUS EXTRA STRENGTH Warner-Lambert Consumer Healthcare Pseudoephedrine HCl-Dextromethorphan HBr-Acetaminophen, Acetaminophen-Dextromethorphan HBr-Guaifenesin-Pseudoephedrine HCl, Pseudoephedrine HCl, Pseudoephedrine HCl, Pseudoephedrine HCl, Pseudoephedrine HCl, Acetaminophen-Pseudoephedrine HCl Nasal Decongestant-Antitussive-Analgesic, Analgesic-Antitussive-Expectorant-Nasal Decongestant, Nasal Decongestant, Nasal Decongestant, Nasal Decongestant, Nasal Decongestant, Analgesic-Nasal Decongestant Indications And Clinical Uses: Cold &…

SUFENTA® Janssen-Ortho Sufentanil Citrate Opioid Analgesic-Adjunct to Anesthesia Action and Clinical Pharmacology: Sufentanil is an opioid analgesic. The analgesic potency of sufentanil is approximately 5 to 7 times that of fentanyl. Dosage requirements for equianalgesic effect will be 1/5 to  1/7 those of fentanyl on a g/kg basis. Assays of histamine in patients administered sufentanil have shown no elevation in plasma histamine levels and no indication of histamine release. I.V….

SULCRATE®, SULCRATE® SUSPENSION PLUS Hoechst Marion Roussel Sucralfate Gastroduodenal Cytoprotective Agent Action and Clinical Pharmacoligy: Sucralfate exerts a generalized gastric cytoprotective effect by enhancing natural mucosal defense mechanisms. Studies conducted in animals and clinical trials in humans have demonstrated that sucralfate can protect the gastric mucosa against various irritants such as alcohol, ASA, hydrochloric acid, sodium hydroxide or sodium taurocholate. In addition, sucralfate has been demonstrated to have a greater…

STRESSTABS®, STRESSTABS® PLUS, STRESSTABS® with IRON, STRESSTABS® with ZINC Whitehall-Robins Vitamin B Complex-Ascorbic Acid-Vitamin E, Vitamin B Complex-Ascorbic Acid-Vitamin E-Selenium-Zinc-Beta Carotene, Vitamin B Complex-Ascorbic Acid-Vitamin E-Iron, Vitamin B Complex-Ascorbic Acid-Vitamin E-Zinc-Copper Dietary Supplement Indications And Clinical Uses: Stresstabs: Dietary supplement in conditions responding to therapy with B complex factors. 1nbStresstabs Plus: When physiologic stress causes severe tissue depletion of the B Complex, vitamins C, A and E. Stresstabs with Iron:…