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SYNALAR® Medicis Fluocinolone Acetonide Topical Corticosteroid Indications And Clinical Uses : For topical therapy of corticosteroid responsive acute and chronic skin eruptions where an anti-inflammatory, anti-allergenic, and antipruritic activity in the topical management is required. Topical solution (0.01%) is more appropriate than the fluocinolone acetonide ointment formulation for use in locations such as the scalp Contra-Indications: Untreated bacterial, tubercular, fungal and most viral lesions of the skin (including herpes simplex,…

SURMONTIL® Rhône-Poulenc Rorer Trimipramine Maleate Antidepressant Action and Clinical Trimipramine is a tricyclic antidepressant with sedative properties. It also has anticholinergic properties and potentiates the sympathetic response, presumably by blocking the reuptake of norepinephrine which has been released by the presynaptic neurons. It has a quinidine-like effect on the heart and an EEG activity similar to that of other tricyclic antidepressants.IndicationsIndications: Indications And Clinical Uses: The drug treatment of depressive…

SURGAM® SURGAM® SR Hoechst Marion Roussel Tiaprofenic Acid Anti-inflammatory–Analgesic Action and Clinical Tiaprofenic acid, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action, as with other nonsteroidal anti-inflammatory agents, is not yet completely known. Tiaprofenic acid is an inhibitor of prostaglandin synthetase enzymes which are known to be associated with inflammation and pain. The therapeutic effect of tiaprofenic acid does not…

SYMMETREL® (Antiparkinson) DuPont Pharma Amantadine HCl Antiparkinson Action and Clinical While the mechanism of action of amantadine in the treatment of Parkinson’s syndrome and drug-induced extrapyramidal reactions is not known, it is believed to release brain dopamine from nerve endings making it more available to activate dopaminergic receptors. The drug does not possess anticholinergic activity in animal tests at doses similar to those used clinically. The antiviral activity of amantadine…

SURVANTA® Abbott Beractant Lung Surfactant Action and Clinical Deficiency of pulmonary surfactant is an important factor in the development of Respiratory Distress Syndrome (RDS) in premature infants. Beractant replenishes surfactant and restores surface activity to the lungs of these infants. It reduces surface tension and concomitantly increases lung compliance.: Intratracheally administered beractant distributes rapidly to the alveolar surfaces and stabilizes the alveoli against collapse during respiration thereby increasing alveolar ventilation….

SUPREFACT® SUPREFACT® DEPOT Hoechst Marion Roussel Buserelin Acetate Luteinizing Hormone Releasing Hormone (LH-RH) Analog Action and Clinical Buserelin is a synthetic peptide analog of the natural gonadotropin releasing hormone (GnRH/LHRH). The substitution of glycine in position 6 by D-serine, and that of glycinamide in position 10 by ethylamide, leads to a nonapeptide with a greatly enhanced LHRH effect. The effects of buserelin on follicle stimulating hormone (FSH) and luteinizing hormone…

SUPREFACT® SUPREFACT® DEPOT Hoechst Marion Roussel Buserelin Acetate Luteinizing Hormone-Releasing Hormone (LH-RH) Analog Action and Clinical Buserelin is a synthetic peptide analog of the natural gonadotropin releasing hormone (GnRH/LHRH). The substitution of glycine in position 6 by D-serine, and that of glycinamide in position 10 by ethylamide, leads to a nonapeptide with a greatly enhanced LHRH effect. The effects of buserelin on follicle stimulating hormone (FSH) and luteinizing hormone (LH)…

SURGAM® SURGAM® SR Hoechst Marion Roussel Tiaprofenic Acid Anti-inflammatory Analgesic Action and Clinical Tiaprofenic acid, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic properties. Its mechanism of action, as with other nonsteroidal anti-inflammatory agents, is not yet completely known. Tiaprofenic acid is an inhibitor of prostaglandin synthetase enzymes which are known to be associated with inflammation and pain. The therapeutic effect of tiaprofenic acid does not…

SUPRES® Merck Frosst Methyldopa-Chlorothiazide Antihypertensive Action and Clinical Methyldopa: Methyldopa, an antihypertensive agent, is an aromatic-amino-acid decarboxylase inhibitor in animals and in man. Although the mechanism of action has yet to be conclusively demonstrated, the antihypertensive effect of methyldopa probably is due to its metabolism to alpha-methyl-norepinephrine, which then lowers arterial pressure by stimulation of central inhibitory alpha-adrenergic receptors, false neurotransmission, and/or reduction of plasma renin activity. Methyldopa has been…

SULTRIN® Janssen-Ortho Triple Sulfa Vaginitis Therapy Indications And Clinical Uses: Postoperative vaginitis or cervicitis, nonspecific vaginitis, ulcerative vaginitis and related gynecological conditions. Contra-Indications: Sulfonamide sensitivity; kidney disease. Precautions: Although some absorption of sulfonamide may occur through the vaginal mucosa, systemic reactions attributable to this are infrequent, as are local sensitivity reactions such as increased discomfort or a burning sensation following the use of this product. However, as with all sulfonamides,…