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HALDOL® Janssen-Ortho Haloperidol Antipsychotic Action And Clinical Pharmacology: Haloperidol is a butyrophenone derivative with antipsychotic properties that has been considered particularly effective in the management of hyperactivity, agitation, and mania. Haloperidol is an effective neuroleptic and also possesses antiemetic properties; it has a marked tendency to provoke extrapyramidal effects and has relatively weak alpha-adrenolytic properties. It may also exhibit hypothermic and anorexiant effects and potentiate the action of barbiturates, general…

GYNE-T® Intrauterine Copper Contraceptive Janssen-Ortho Intrauterine Copper Intrauterine Contraceptive Description: The Gyne-T copper intrauterine consists of a polyethylene support in the shape of a “T” (horizontal arm 32 mm in length and 1.59 mm in diameter. The vertical arm is 36 mm in length and 1.52 mm in diameter. The “T” carries 120 mg of copper wire (0.25 mm in diameter; 265 mm in length) wound around the vertical arm…

GUAIFENESIN General Monograph Glyceryl Guaiacolate Expectorant Pharmacology: Guaifenesin is believed to produce its effect through a local or reflex irritant action that activates the vagus nerve to stimulate secretion or respiratory tract fluid. This is thought to increase sputum volume, decrease its viscosity, enhance the flow of less viscid secretions and promote mucociliary clearance. Pharmacokinetics: The drug is rapidly absorbed from the gastrointestinal tract and excreted in the urine. Indications:…

GYNECURE™ Pfizer Consumer Tioconazole Antifungal Agent Action And Clinical Pharmacology: Tioconazole is a member of the imidazole class of antifungal agents. Although the mode of action of tioconazole has not as yet been determined, several studies have demonstrated that the imidazoles inhibit ergosterol synthesis in fungi by blocking C-14 demethylation. As a result, there is an accumulation of C-14 methyl sterol intermediates like langosterol, and a decrease in ergosterol. Langosterol…

GYNE-T® 380 Slimline Intrauterine Copper Contraceptive Janssen-Ortho Intrauterine Copper Contraceptive Intrauterine Contraception Description: The intrauterine device consists of a polyethylene support in the shape of a “T”. The horizontal arm is 32 mm in length and 1.59 mm in diameter. The vertical arm is 36 mm in length and 1.52 mm in diameter. The vertical arm has at its tip a spherical enlargement, 0.3 mm in diameter. The “T” carries…

GRAVOL® Preparations Carter Horner Dimenhydrinate Antiemetic – Antivertigo Indications And Clinical Uses: Prevention or relief of motion sickness, radiation sickness, postoperative vomiting, and drug induced nausea and vomiting; it has also been used for the symptomatic relief of nausea and vertigo due to Meniere’s disease and other labyrinthine disturbances. Contra-Indications: Glaucoma, chronic lung disease, difficulty in urination due to prostatic hypertrophy. Manufacturers’ Warnings In Clinical States: As dimenhydrinate has a…

GRISOVIN® FP Roberts Griseofulvin Microcrystalline Antifungal Antibiotic Indications And Clinical Uses: Orally effective against superficial infections caused by those fungi responsible for dermatomycoses in man and animals, namely: M. canis, M. gypseum, M. audouini, E. floccosum, T. tonsurans, T. rubrum, T. mentagrophytes, T. magnini, T. gallinae, T. verrucosum, T. sulfureum, T. interdigitale, T. schoenleini, T. crateriform. Griseofulvin is inactive against: C. albicans (monilia), C. neoformans, B. dermatitidis, A. israeli, H….

GLYSENNID® Novartis Consumer Health Sennosides Laxative Action And Clinical Pharmacology: Glysennid is a laxative which selectively stimulates the colon 8 to 12 hours after ingestion. Therefore, if Glysennid is taken before retiring, sleep is usually not disturbed. Indications And Clinical Uses: Atonic constipation (e.g., in the elderly, after surgery, in the puerperium or due to neurological disorders). Contra-Indications: Known hypersensitivity to sennosides or any of the ingredients; appendicitis, intestinal hemorrhage,…

GONAL-F® Serono Follitropin alpha (rDNA origin) Gonadotropin Action And Clinical Pharmacology: Gonal-F is a gonadotropin preparation of recombinant DNA origin. The active ingredient, recombinant human follicle stimulating hormone (r-hFSH), is a human glycoprotein hormone which consists of 2 noncovalently linked, nonidentical protein components designated as the a- and b-subunits. The physicochemical, immunological, and biological activities of r-hFSH are similar to those of human menopausal urine-derived hFSH, but free of urinary…

GOOD START® Nestle, Carnation Infant Formula Indications And Clinical Uses: A nutritionally complete iron fortified infant formula for routine feeding of infants from birth if breast-feeding is not an option or if a supplement is required. Good Start has the added benefit of being easier to tolerate than routine cow’s milk or soy based formula because the protein has been partially broken down to reduce the possibility of an allergic…