You searched for : 'C'

CLARITIN® EXTRA Schering Loratadine – Pseudoephedrine Sulfate Histamine H1-Receptor Antagonist – Sympathomimetic Amine Action And Clinical Pharmacology: Loratadine is a long-acting tricyclic antihistamine with selective peripheral H1 receptor antagonistic activity. It exhibits a dose-related inhibition of the histamine-induced skin wheal and flare response in humans which is rapid in onset, is apparent at 2 hours and persists throughout the 24 hour observation period. Single oral doses up to 160 mg…

CLARITIN® Schering Loratadine Histamine H1-Receptor Antagonist Action And Clinical Pharmacology: Loratadine is a long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonistic activity. It exhibits a dose-related inhibition of the histamine-induced skin wheal and flare response in humans which is rapid in onset, is apparent at 2 hours and persists throughout the 24-hour observation period. Single oral doses up to 160 mg and repeat daily doses of 40 mg for up…

CITRO-MAG® Rougier Magnesium Citrate Laxative Indications And Clinical Uses: A laxative or purgative. Preparation of the colon for x-ray examination. Contra-Indications: Abdominal pain, nausea or vomiting. Known or suspected intestinal obstruction. Precautions: Frequent or prolonged use may result in dependence on laxatives. Dosage: Adults: as a laxative: 1/4 to 1/2 bottle; as a purgative: 1 bottle before breakfast or as prescribed before x-ray examination. Children (6 to 12 years): 30…

CITROCARBONATE® Roberts Bicarbonate – Tartrate Compound Urinary Alkalizer Indications And Clinical Uses: As a systemic and urinary alkalinizer, gastric antacid. Precautions: Consider the sodium content in administration to patients on sodium free diets. Chronic, prolonged use may produce metabolic alkalosis. Dosage And Administration: Adults: 1 to 2 teaspoonfuls of powder in a glass of cold water, 15 minutes to 2 hours after meals, or as directed by a physician. Children:…

CILOXAN® Alcon Ciprofloxacin HCl Antibacterial Agent Action And Clinical Pharmacology: The bactericidal action of ciprofloxacin results from inhibition of the enzyme, DNA gyrase, which is required for the synthesis of bacterial DNA. Pharmacokinetics: Topically applied ciprofloxacin ophthalmic solution is absorbed systemically with ciprofloxacin plasma concentrations approaching steady state at the end of dosing each day. Ciprofloxacin plasma concentrations following a routine ophthalmic treatment regimen were in the range of nonquantifiable…

CIPRO® CIPRO® I.V. CIPRO® Oral Suspension Bayer Ciprofloxacin HCl Ciprofloxacin Ciprofloxacin Antibacterial Action And Clinical Pharmacology: Ciprofloxacin, a synthetic fluoroquinolone, has a bactericidal mode of action. This action is achieved through inhibition of DNA gyrase, an essential component of the bacterial DNA replication system. Inhibition of the alpha subunit of the DNA gyrase blocks the resealing of the nicks on the DNA strands induced by this alpha subunit, leading to…

CISPLATIN INJECTION Faulding Antineoplastic Action And Clinical Pharmacology: Cisplatin is thought to act by producing inter-strand and intra-strand cross-links of cellular DNA in a similar manner to bifunctional alkylating agents. It does not appear to be cell-cycle specific. Using radioactive platinum, a high uptake of the drug was found in kidneys, liver and intestines with poor penetration of the CNS. An initial plasma half-life of 25 to 49 minutes and…

CITANEST® 4% PLAIN CITANEST® 4% FORTE Astra Prilocaine HCl Prilocaine HCl – Epinephrine Local Anesthetic for Infiltration and Nerve Block Action And Clinical Pharmacology: Mechanism of Action: Prilocaine stabilizes the neuronal membrane and prevents the initiation and transmission of nerve impulses thereby, effecting local anesthetic action. Local anesthetics of the amide type are thought to act within sodium channels of the nerve membrane. Onset of Action: When used for infiltration…

CIDOMYCIN® Hoechst Marion Roussel Gentamicin Antibiotic Action And Clinical Pharmacology: Gentamicin is a bactericidal antibiotic which affects bacterial growth by specific inhibition of normal protein synthesis in susceptible bacteria. Gentamicin Serum Levels Via the I.M. Route in Adults and Children: In patients with normal renal function, peak serum concentrations, bactericidal for susceptible bacteria, occur between 30 and 90 minutes after injection. The peak serum level (mg/L) is usually 4 times…

CHYMODIACTIN® Knoll Chymopapain Proteolytic Enzyme Action And Clinical Pharmacology: Chymopapain for intradiscal injection is injected into the herniated nucleus pulposus of the lumbar intervertabral disc resulting in rapid hydrolysis of the noncollagenous polypeptides or proteins that maintain the tertiary structure of the chondromucoprotein. This lessens the intradiscal osmotic activity, thereby decreasing fluid absorption and reducing intradiscal pressure. The foregoing mechanism of action is based on animal in vitro and in…