You searched for : 'C'

MALARONE™ Glaxo Wellcome Atovaquone – Proguanil HCl Antimalarial Action And Clinical Pharmacology: The constituents of Malarone, interfere with 2 different pathways involved in the biosynthesis of pyrimidines required for nucleic acid replication. Atovaquone is a selective inhibitor of parasite mitochondrial electron transport. Proguanil exerts its effect primarily by means of the metabolite cycloguanil, a dihydrofolate reductase inhibitor. Inhibition of dihydrofolate reductase in the malaria parasite disrupts deoxythymidylate synthesis. These two…

MANDOL® Lilly Cefamandole Nafate Antibiotic Action And Clinical Pharmacology: Cefamandole, a semisynthetic cephalosporin antibiotic, possesses properties similar to other members of this group, but has a broader spectrum of activity particularly with respect to the treatment of Gram-negative bacillary infections. Cefamandole has been shown to be active against the following organisms in vitro: Gram-positive: b-hemolytic and other strains of streptococci including S. pneumoniae (many strains of S. faecalis are resistant),…

MACROBID® Procter & Gamble Pharmaceuticals Nitrofurantoin Monohydrate – Nitrofurantoin Macrocrystals Urinary Tract Antibacterial Action And Clinical Pharmacology: Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates which inactivate or alter bacterial ribosomal proteins and other macromolecules. As a result of such inactivations, the vital biochemical processes of protein synthesis, aerobic energy metabolism, DNA synthesis, RNA synthesis and cell wall synthesis are inhibited. The broad-based nature of this mode of action…

MACRODANTIN® Procter & Gamble Pharmaceuticals Nitrofurantoin Macrocrystals Urinary Tract Antibacterial Action And Clinical Pharmacology: Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates which inactivate or alter bacterial ribosomal proteins and other macromolecules. As a result of such inactivations, the vital biochemical processes of protein synthesis, aerobic energy metabolism, DNA synthesis, RNA synthesis and cell wall synthesis are inhibited. The broad-based nature of this mode of action may explain the…

MAGNESIUM SULFATE Abbott Anticonvulsant – Electrolyte Replenisher Action And Clinical Pharmacology: Magnesium (Mg++) is an important cofactor for enzymatic reactions and plays an important role in neurochemical transmission and muscular excitability. As a nutritional adjunct in hyperalimentation, the precise mechanism of action for magnesium is uncertain. Early symptoms of hypomagnesemia (less than 1.5 mEq/L) may develop as early as 3 to 4 days or within weeks. Predominant deficiency effects are…

MAALOX® PLUS EXTRA STRENGTH Novartis Consumer Health Magnesium Hydroxide – Aluminum Hydroxide – Simethicone Antacid – Antiflatulent Indications And Clinical Uses: For symptomatic relief of hyperacidity, acid indigestion, heartburn and gas. Contra-Indications: Alkalosis; hypermagnesemia; where distention may be due to partial or complete intestinal obstruction. Not recommended for severely debilitated patients or those with impaired renal function. Precautions: Magnesium salts, in the presence of renal insufficiency, may cause CNS depression….

MAALOX® PLUS Novartis Consumer Health Magnesium Hydroxide – Aluminum Hydroxide – Simethicone Antacid – Antiflatulent Indications And Clinical Uses: For symptomatic relief of hyperacidity, acid indigestion, heartburn and gas. Contra-Indications: Alkalosis; hypermagnesemia; where distention may be due to partial or complete intestinal obstruction. Not recommended for severely debilitated patients or those with impaired renal function. Precautions: See Maalox monograph. Symptoms And Treatment Of Overdose: Symptoms and Treatment: See Maalox monograph….

MAALOX® TC Novartis Consumer Health Magnesium Hydroxide – Aluminum Hydroxide Antacid Indications And Clinical Uses: A high potency antacid for the treatment and relief of the symptoms of peptic ulcer and severe hyperacidity related disorders. Contra-Indications: Alkalosis, hypermagnesemia; where distention may be due to partial or complete intestinal obstruction. Not recommended for severely debilitated patients or those with impaired renal function. Precautions: Magnesium salts in the presence of renal insufficiency…

MAALOX H2 ACID CONTROLLER™ Novartis Consumer Health Famotidine Histamine H2 Receptor Antagonist Action And Clinical Pharmacology: Famotidine is a competitive inhibitor of histamine H2-receptors. The primary clinically important pharmacologic activity of famotidine is inhibition of gastric juice secretion. Famotidine reduces the acid and pepsin content, as well as the volume, of basal, nocturnal, and stimulated gastric secretion. Indications And Clinical Uses: In the treatment of the following conditions where a…

MYOFLEX® Bayer Consumer Triethanolamine Salicylate Topical Analgesic Indications And Clinical Uses: Analgesic rub for the temporary relief of aches and pains of muscles and joints associated with backache, lumbago, neck ache, arthritic or rheumatic pain, strains, sprains, pain of tendons and ligaments. Contra-Indications: Salicylate hypersensitivity. Manufacturers’ Warnings In Clinical States: For external use only. Use only as directed. Keep this and all other drugs out of the reach of children….