You searched for : 'C'

PRIMAXIN® MSD Imipenem – Cilastatin Sodium Antibiotic Action And Clinical Pharmacology: Imipenem exerts a bactericidal action by inhibiting cell wall synthesis in aerobic and anaerobic gram-positive and gram-negative bacteria. Primaxin consists of 2 components: imipenem, a derivative of thienamycin, a carbapenem antibiotic; and cilastatin sodium, a specific inhibitor of dehydropeptidase-I a renal enzyme which metabolizes and inactivates imipenem. Cilastatin blocks the metabolism of imipenem in the kidney, so that concomitant…

PRIMENE® Clintec Amino Acids I.V. Nutritive Supplement Action And Clinical Pharmacology: Primene is a sterile, nonpyrogenic, hypertonic solution of essential and nonessential amino acids in a Pharmacy Bulk Package. A Pharmacy Bulk Package is a container of a sterile preparation for parenteral use in a pharmacy admixture program and is restricted to the preparation of admixtures for i.v. infusion. Primene provides a mixture of essential and nonessential amino acids as…

PRESUN® ULTRA 30 Preparations Westwood-Squibb Octyl Methoxycinnamate – Octyl Salicylate – Oxybenzone – Butyl Methoxydibenzoyl – Methane (Parsol® 1789) Sunscreen Indications And Clinical Uses: A waterproof, non-PABA sunscreen for extremely sun-sensitive patients, or those patients who exhibit a sensitivity to PABA or its esters. Offers maximum UVA and UVB sun protection. Regular usage may help prevent premature aging and wrinkling of the skin due to sun overexposure. Precautions: For external…

PREVACID® Abbott Lansoprazole H KATPase Inhibitor Note: When used in combination with antimicrobials for the eradication of H. pylori, the product monograph for those agents should be consulted. Action And Clinical Pharmacology: Lansoprazole inhibits the gastric H KATPase (the proton pump) which catalyzes the exchange of Hand K It is effective in the inhibition of both basal acid secretion and stimulated acid secretion. In healthy subjects, single and multiple doses…

PREMARIN® TABLETS Wyeth-Ayerst Conjugated Estrogens Estrogenic Hormones Action And Clinical Pharmacology: Estrogen drug products act by regulating the transcription of a limited number of genes. They may act directly at the cell’s surface via non “estrogen receptor” mechanism or directly with the estrogen receptor inside the cell. Estrogens diffuse through cell membranes, distribute themselves throughout the cell, and bind to and activate the nuclear estrogen receptor, a DNA-binding protein which…

PRENAVITE® Roberts Iron – Calcium – Vitamins Prenatal Supplement With Folic Acid Indications And Clinical Uses: As a dietary supplement to meet increased needs in pregnancy and lactation. Contra-Indications: Hemosiderosis, hemochromatosis, hemolytic anemias. Precautions: Neurologic involvement may develop or progress, despite temporary remission of anemia, in patients with pernicious anemia who receive more than 100 g of folic acid per day and who are inadequately treated with vitamin B12. Periodic…

PREPARATION H® CLEANSING PADS PREPARATION H® COOLING GEL PREPARATION H® CREAM PREPARATION H® OINTMENT PREPARATION H® SUPPOSITORIES Whitehall-Robins Hamamelis Water – Glycerin Phenylephrine HCI – Hamamelis Water Live Yeast Derivative (Bio-Dyne) – Shark Liver Oil Live Yeast Derivative (Bio-Dyne) – Shark Liver Oil Live Yeast Derivative (Bio-Dyne) – Shark Liver Oil Hemorrhoid Therapy – Anal Hygiene Hemorrhoidal Treatment Indications And Clinical Uses: Cleansing Pads: hemorrhoidal, toilet tissue irritation, anal cleansing…

PREPULSID® Janssen-Ortho Cisapride Monohydrate Gastrointestinal Prokinetic Agent Action And Clinical Pharmacology: Cisapride is a gastrokinetic drug whose activity is considered to be due to enhancement of the physiological release of acetylcholine at the myenteric plexus. Cisapride increases esophageal peristaltic activity and lower esophageal sphincter tone, thereby decreasing reflux of gastric contents into the esophagus and improving esophageal clearance. Gastric and duodenal emptying are also enhanced by cisapride as a consequence…

PRAVACHOL® Squibb Pravastatin Sodium Lipid Metabolism Regulator Action And Clinical Pharmacology: Pravastatin is one of a new class of lipid-lowering compounds known as HMG-CoA reductase inhibitors (statins) that reduce cholesterol biosynthesis. These agents are competitive inhibitors of 3-hydroxy- 3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the early rate-limiting step in cholesterol biosynthesis, conversion of HMG-CoA to mevalonate. Pravastatin is isolated from a strain of Penicillium citrinum. The active drug substance…

PRE-PEN® Rivex Pharma Benzylpenicilloyl-Polylysine Diagnostic – Penicillin Allergy Action And Clinical Pharmacology: The major antigenic determinant of penicillin hypersensitivity is the penicilloyl group, a degradation product of penicillin. Pre-Pen reacts specifically with penicilloyl skin sensitizing antibodies (reagins) to produce immediate wheal and flare reactions which may reflect increased risk of allergic reactions to subsequent penicillin therapy. Indications And Clinical Uses: As a skin test reagent for the detection of penicilloyl…