You searched for : 'C'

ALSOY™ Nestl©, Carnation Soy Infant Formula Indications And Clinical Uses: A nutritionally complete iron fortified soya brand formula for routine feeding of infants from birth if breast-feeding is not an option or if a supplement is required. For milk-free feeding if a soy supplement is required. Dosage And Administration: As determined by the individual infant’s needs for the first year of life. Consult the physician for specific feeding recommendations. Preparation:…

ALPHAGAN™ Allergan Brimonidine Tartrate Elevated Intraocular Pressure Therapy Action And Clinical Pharmacology: Mechanism of Action: Brimonidine is a relatively selective alpha adrenergic receptor agonist that in radioligand binding assays and in functional assays, is approximately 1 000 times more selective for the alpha-2 adrenoceptor than the alpha-1 adrenoceptor. This selectivity results in the absence of vasoconstriction in microvessels associated with human retinal xenografts. Topical administration of brimonidine decreases intraocular pressure…

ALKERAN® Glaxo Wellcome Melphalan Antineoplastic Action And Clinical Pharmacology: Melphalan is an alkylating agent of the bischloroethylamine type. As a result, its cytotoxicity appears to be related to the extent of its interstrand cross-linking with DNA, probably by binding at the Nposition of guanine. Like other bifunctional alkylating agents, it is active against both resting and rapidly dividing tumor cells. Pharmacokinetics: The pharmacokinetics of melphalan after i.v. administration have been…

ALLOPURINOL General Monograph, CPhA Xanthine Oxidase Inhibiton This monograph has been compiled by CPhA. It may contain information different from that approved by HPB, Health Canada, and the pharmaceutical manufacturers’ approval has not been requested. Pharmacology: Allopurinol and its active metabolite, oxypurinol, inhibit xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and of xanthine to uric acid. Inhibition of this enzyme accounts for the major pharmacological…

ALOMIDE® Alcon Lodoxamide Tromethamine Anti-allergy Agent Action And Clinical Pharmacology: Lodoxamide, a mast cell stabilizer inhibits the in vivo type I immediate hypersensitivity reaction in animals and man. In vitro studies have demonstrated the ability of lodoxamide to stabilize mast cells and prevent the antigen specific induced release of histamine. In addition, lodoxamide prevents the release of other mast cell inflammatory mediators (i.e., SRS-A, slow reacting substances of anaphylaxis also…

  ALESSE™ 21 ALESSE™ 28 Wyeth-Ayerst Levonorgestrel – Ethinyl Estradiol Oral Contraceptive Action And Clinical Pharmacology: Although the primary mechanism of action is inhibition of ovulation, the effectiveness of Alesse may also result from other mechanisms of action, such as hostility of the cervical mucus to sperm penetration and migration. Indications And Clinical Uses: For conception control. Contra-Indications: History of or actual thrombophlebitis or thromboembolic disorders. History of or actual…

ALIMENTUM® Abbott Infant Feeding Formula Indications And Clinical Uses: A nutritionally complete formula for infants and children with milk and/or soy protein allergy, severe food allergies, colic due to milk sensitivity, select cases of chronic diarrhea or maldigestion/malabsorption. Precautions: Shake very well to assure proper blending. Because of the special nutritional characteristics of Alimentum, it does not look or taste like milk or soy formulations. This is a ready-to-feed formula;…

ALBERT® GLYBURIDE Albert Pharma Glyburide Oral Hypoglycemic Action And Clinical Pharmacology: The principal action of glyburide results in an increased insulin release from the beta cells of the pancreas. Other mechanisms leading to a reduction of blood glucose are also believed to be influenced by glyburide. The insertion of an alkylene chain on the benzene nucleus results in a product of very high potency. Schulz and Schmidt indicated that the…

ALBERT® PENTOXIFYLLINE Albert Pharma Pentoxifylline Vasoactive Agent Action And Clinical Pharmacology: Pentoxifylline is a xanthine derivative. It belongs to a group of vasoactive drugs which improve peripheral blood flow and thus enhance peripheral tissue oxygenation. The mechanism by which pentoxifylline achieves this effect has not been determined, but it is likely that the following factors are involved: Pentoxifylline, as other xanthine derivatives, relaxes certain smooth muscles including those of the…

AIROMIR™ 3M Pharmaceuticals Salbutamol Sulfate Bronchodilator – b2-adrenergic Stimulant Action And Clinical Pharmacology: Salbutamol produces bronchodilation through stimulation of b2-adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of bronchial muscle fibers. This action results in improved pulmonary function as demonstrated by spirometric measurements. At therapeutic doses, salbutamol has little action on the b1-adrenergic receptors in cardiac muscle. Clinical experience has shown that inhaled salbutamol, like other b-adrenergic agonists, can…