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BIQUIN DURULES® Astra Controlled Release Quinidine Bisulfate Antiarrhythmic Agent Action And Clinical Pharmacology: Quinidine is a class IA antiarrhythmic agent according to the modified Vaughan-Williams classification. Quinidine is considered a myocardial depressant. Direct actions on the heart include: decreased myocardial excitability; prolongation of the atrial, ventricular and Purkinje refractory periods; decreased atrial, Purkinje and ventricular conduction velocities; substantially decreased firing rate of cardiac Purkinje fibres by direct action; decreased myocardial…

BEZALIP® Roche Bezafibrate Lipid Metabolism Regulator Action And Clinical Pharmacology: The fibrates, including bezafibrate, lower elevated serum lipids by decreasing the low density lipoprotein (LDL) fraction rich in cholesterol and the very low density lipoprotein (VLDL) fraction rich in triglycerides. In addition, fibrates (including bezafibrate) increase the high density lipoprotein (HDL) cholesterol fraction. Due to their major action on lipoprotein and hepatic triglyceride lipase, the fibrates appear to produce a…

BETASERON® Berlex Canada Interferon beta-1b Immunomodulator Action And Clinical Pharmacology: General: Interferons are a family of naturally occurring proteins, which have molecular weights ranging from 15 000 to 21 000 daltons. Three major classes of interferons have been identified: alpha, beta and gamma. Interferon beta-1b, interferon alpha, and interferon gamma have overlapping yet distinct biologic activities. The activities of interferon beta-1b are species-restricted and, therefore, the most pertinent pharmacological information…

BETNESOL® Preparations Roberts Betamethasone Sodium Phosphate Corticosteroid Indications And Clinical Uses: Enema: For local use as a retention enema in ulcerative colitis. Eye and Ear Drops: Inflammatory eye conditions (anterior segment) and inflammatory ear conditions, e.g., otitis externa. Tablets: Acute asthma, intractable hay fever, severe eczema, other inflammatory skin diseases; rheumatoid arthritis, nephrotic syndrome, severe ulcerative colitis, collagen diseases. Contra-Indications: Systemic infections, live virus immunization, hypersensitivity. Precautions: In patients on…

BETADINE® Vaginal Preparations Purdue Frederick Povidone-Iodine Bactericidal – Trichomonacidal – Fungicidal Action And Clinical Pharmacology: Betadine is iodine complexed with povidone (polyvinyl-pyrrolidone). The compound is soluble in water forming a golden brown solution. Like iodine, the solution of the iodine complex is bactericidal, trichomonacidal, fungicidal and virucidal. Unlike solutions of iodine it is nonstaining to skin and natural fabrics. The antiseptic action is due to the available iodine present in…

BETAGAN® Allergan Levobunolol HCl Glaucoma Therapy Action And Clinical Pharmacology: Levobunolol is a noncardioselective beta- adrenoceptor antagonist, equipotent at both beta1 and beta2 receptors. Levobunolol is approximately 60 times more potent than the dextro isomer in its beta-blocking activity, yet equipotent in its potential for direct myocardial depression. Accordingly, the levo isomer, levobunolol, is used. Levobunolol does not have significant local anesthetic (membrane-stabilizing) effect or intrinsic sympathomimetic activity. Beta-adrenergic receptor…

BENZTROPINE MESYLATE Antiparkinsonian Agent Pharmacology: Benztropine is a synthetic tertiary amine with structural similarities to atropine and diphenhydramine. Benztropine exhibits anticholinergic, antihistaminic and local anesthetic properties. Its mechanism of action as an antiparkinsonian agent is not clearly known. The pharmacologic effects of the drug may not be apparent until 2 to 3 days after initiation of therapy and may persist for up to 24 hours after discontinuation of the drug….

BENYLIN® CODEINE 3.3 mg-D-E (OTC) BENYLIN® DM BENYLIN® DM 12 HOUR BENYLIN® DM FOR CHILDREN BENYLIN® DM FOR CHILDREN 12 HOUR BENYLIN® DM-D (ADULT) BENYLIN® DM-D FOR CHILDREN BENYLIN® DM-D-E BENYLIN® DM-D-E EXTRA STRENGTH BENYLIN® DM-E BENYLIN® DM-E EXTRA STRENGTH BENYLIN® E EXTRA STRENGTH BENYLIN® 4 FLU Warner-Lambert Consumer Healthcare Codeine Phosphate – Pseudoephedrine HCl – Guaifenesin Dextromethorphan HBr Dextromethorphan HBr – Pseudoephedrine HCl Dextromethorphan HBr – Pseudoephedrine HCl –…

BENZODIAZEPINES Alprazolam Bromazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Diazepam Flurazepam Lorazepam Midazolam Nitrazepam Oxazepam Temazepam Triazolam Anticonvulsant – Anxiolytic – Hypnotic – Sedative Action And Clinical Pharmacology: Benzodiazepines are glycoproteins with an affinity for benzodiazepine receptors which act as specific binding sites for gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the CNS. Although various mechanisms of action have been proposed, the precise sites and mechanisms of action have not…

BENADRYL® ALLERGY/SINUS/HEADACHE Warner-Lambert Consumer Healthcare Diphenhydramine HCl – Pseudoephedrine HCl – Acetaminophen Antihistaminic – Decongestant – Analgesic Indications And Clinical Uses: For relief of sneezing, runny nose, itchy watery eyes, sinus and nasal congestion, sinus pain and headache. Precautions: Occupational Hazards: May cause drowsiness, use caution when driving a motor vehicle or operating machinery. A physician should be consulted prior to using this product if patient has chronic alcoholism, serious…