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GONAL-F® Serono Follitropin alpha (rDNA origin) Gonadotropin Action And Clinical Pharmacology: Gonal-F is a gonadotropin preparation of recombinant DNA origin. The active ingredient, recombinant human follicle stimulating hormone (r-hFSH), is a human glycoprotein hormone which consists of 2 noncovalently linked, nonidentical protein components designated as the a- and b-subunits. The physicochemical, immunological, and biological activities of r-hFSH are similar to those of human menopausal urine-derived hFSH, but free of urinary…

GOOD START® Nestle, Carnation Infant Formula Indications And Clinical Uses: A nutritionally complete iron fortified infant formula for routine feeding of infants from birth if breast-feeding is not an option or if a supplement is required. Good Start has the added benefit of being easier to tolerate than routine cow’s milk or soy based formula because the protein has been partially broken down to reduce the possibility of an allergic…

GELUSIL® GELUSIL® EXTRA STRENGTH Warner-Lambert Consumer Healthcare Aluminum Hydroxide – Magnesium Hydroxide Antacid Indications And Clinical Uses: For the temporary relief and treatment of duodenal and stomach ulcers, gastritis, hiatus hernia, esophagitis, heartburn and any similar gastrointestinal disorders in which control of gastric hyperacidity is desirable. Contra-Indications: Should not be given to patients who are severely debilitated or suffering from kidney failure, alkalosis or hypermagnesemia. Precautions: Antacids can interfere with…

GELFOAM® Pharmacia & Upjohn Absorbable Gelatin Hemostatic Description: Gelfoam is a medical device, intended for application to bleeding surfaces as a hemostatic. It is a water-insoluble, off-white, nonelastic, porous, pliable product prepared from purified pork Skin Gelatin USP granules and Water for injection, USP and is able to absorb and hold within its interstices, many times its weight of blood and other fluids. Gelfoam sterile powder is a fine, dry,…

GELFILM® Pharmacia & Upjohn Absorbable Gelatin Film Surgical Implant Description: Gelfilm Sterile Film and Gelfilm Sterile Ophthalmic Film are absorbable gelatin film approximately 0.075 mm in thickness, designed for use as an absorbable gelatin implant in neurosurgery and thoracic and ocular surgery. In the dry state absorbable gelatin film has the appearance and texture of cellophane of equivalent thickness; when moistened, it assumes a rubbery consistency and can be cut…

GAMIMUNE® N Bayer Immune Globulin (Human), I.V. Passive Immunizing Agent Action And Clinical Pharmacology: Primary Humoral Immunodeficiency: Gamimune N treated with solvent/detergent supplies a broad spectrum of opsonic and neutralizing IgG antibodies for the prevention or attenuation of a wide variety of infectious diseases. Since Gamimune N is administered i.v., essentially 100% of the infused IgG antibodies are immediately available in the recipient’s circulation. Studies using a modified i.v. immunoglobulin…

FROBEN® FROBEN SR® Knoll Flurbiprofen Nonsteroidal Anti-inflammatory Agent Action And Clinical Pharmacology: Flurbiprofen is a nonsteroidal anti-inflammatory drug with analgesic and antipyretic activity. Although its mechanism of action has not been completely elucidated it has been shown to be an inhibitor of prostaglandin synthesis, specifically cyclo-oxygenase, and to some extent lipoxygenase, and is not due to pituitary-adrenal stimulation. Flurbiprofen is well absorbed and the rate of absorption is not altered…

FOSAMAX® MSD Alendronate Sodium Bone Metabolism Regulator Action And Clinical Pharmacology: Alendronate is an aminobisphosphonate that acts as a potent, specific inhibitor of osteoclast-mediated bone resorption. Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone. Pharmacokinetics: Absorption: Relative to an i.v. reference dose, the mean oral bioavailability of alendronate in women was 0.7% for doses ranging from 5 to 40 mg when administered after an…

FRAGMIN® Pharmacia & Upjohn Dalteparin Sodium Anticoagulant – Antithrombotic Action And Clinical Pharmacology: Dalteparin is an antithrombotic agent. Dalteparin sodium (low molecular weight heparin sodium) has an average molecular weight of 5 000. Dalteparin is produced through controlled nitrous acid de-polymerization of sodium heparin from porcine intestinal mucosa. It is composed of strongly acidic sulfated polysaccharide chains with an average molecular weight of 5 000 and about 90% of the…

FOLLOW-UP SOY® Nestl©, Carnation Soy Infant Formula Indications And Clinical Uses: A soy based, iron fortified formula designed to meet the nutritional needs of babies from 6 to 12 months of age who are already eating baby foods. Follow-Up soy formula is designed to be the liquid portion of a 6 to 12 month old baby’s diet. It is a nutritionally superior formula for milk-free feeding for babies 6 to…