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HEPALEAN® Organon Teknika Heparin Sodium Anticoagulant Indications And Clinical Uses: Used in the treatment of thrombophlebitis, phlebothrombosis, and cerebral, coronary, and retinal vessel thrombosis to prevent extension of clots and thromboembolic phenomena. Also used prophylactically to prevent the occurrence of thromboembolism, and to prevent clotting during dialysis and other surgical procedures, particularly vascular surgery. When using in conjuction with dialysis machines or where heparin is added to glucose or saline…

HEPARIN LEO® Leo Heparin Sodium Anticoagulant Action And Clinical Pharmacology: Heparin is an anticoagulant which prevents the formation of thrombin by accelerating the neutralization of activated coagulation factors by naturally occurring inhibitors. Indications And Clinical Uses: For the prophylaxis and management of intravascular clotting and embolism in susceptible patients. It is also used in extra-corporeal circulation, i.e. heart-lung and renal dialysis machines and blood transfusions. Contra-Indications: Hemorrhagic disorders and patients…

HEPARIN: UNFRACTIONATED General Monograph Heparin Sodium Anticoagulant Action And Clinical Pharmacology: Heparin is a heterogeneous preparation of sulfated mucopolysaccharide polymers whose molecular weights range from 3 000 to 30 000 daltons, averaging between 12 000 and 15 000 daltons. Heparin exerts its anticoagulant activity by reversibly binding to antithrombin III (AT III), accelerating the ability of AT III to neutralize thrombin and activated coagulation factor X (Xa). The heparin-AT III…

HALFAN™ SmithKline Beecham Halofantrine HCl Antimalarial Action And Clinical Pharmacology: Halofantrine is schizonticidal and exerts its action at the erythrocytic stage of the life cycle (trophozoite and schizont). It is not effective against exo-erythrocytic (hepatic) schizonts or against the sporozoite, merozoite or gametozoite stages of the life cycle of Plasmodium species investigated. The precise mechanism of action of halofantrine is not certain. It has been hypothesized that halofantrine interferes with…

HALOTESTIN® Pharmacia & Upjohn Fluoxymesterone Androgenic – Anabolic Steroid Action And Clinical Pharmacology: Endogenous androgens are responsible for normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body…

HALDOL® Janssen-Ortho Haloperidol Antipsychotic Action And Clinical Pharmacology: Haloperidol is a butyrophenone derivative with antipsychotic properties that has been considered particularly effective in the management of hyperactivity, agitation, and mania. Haloperidol is an effective neuroleptic and also possesses antiemetic properties; it has a marked tendency to provoke extrapyramidal effects and has relatively weak alpha-adrenolytic properties. It may also exhibit hypothermic and anorexiant effects and potentiate the action of barbiturates, general…

GYNE-T® Intrauterine Copper Contraceptive Janssen-Ortho Intrauterine Copper Intrauterine Contraceptive Description: The Gyne-T copper intrauterine consists of a polyethylene support in the shape of a “T” (horizontal arm 32 mm in length and 1.59 mm in diameter. The vertical arm is 36 mm in length and 1.52 mm in diameter. The “T” carries 120 mg of copper wire (0.25 mm in diameter; 265 mm in length) wound around the vertical arm…

GRAVOL® Preparations Carter Horner Dimenhydrinate Antiemetic – Antivertigo Indications And Clinical Uses: Prevention or relief of motion sickness, radiation sickness, postoperative vomiting, and drug induced nausea and vomiting; it has also been used for the symptomatic relief of nausea and vertigo due to Meniere’s disease and other labyrinthine disturbances. Contra-Indications: Glaucoma, chronic lung disease, difficulty in urination due to prostatic hypertrophy. Manufacturers’ Warnings In Clinical States: As dimenhydrinate has a…

GRISOVIN® FP Roberts Griseofulvin Microcrystalline Antifungal Antibiotic Indications And Clinical Uses: Orally effective against superficial infections caused by those fungi responsible for dermatomycoses in man and animals, namely: M. canis, M. gypseum, M. audouini, E. floccosum, T. tonsurans, T. rubrum, T. mentagrophytes, T. magnini, T. gallinae, T. verrucosum, T. sulfureum, T. interdigitale, T. schoenleini, T. crateriform. Griseofulvin is inactive against: C. albicans (monilia), C. neoformans, B. dermatitidis, A. israeli, H….

GLYSENNID® Novartis Consumer Health Sennosides Laxative Action And Clinical Pharmacology: Glysennid is a laxative which selectively stimulates the colon 8 to 12 hours after ingestion. Therefore, if Glysennid is taken before retiring, sleep is usually not disturbed. Indications And Clinical Uses: Atonic constipation (e.g., in the elderly, after surgery, in the puerperium or due to neurological disorders). Contra-Indications: Known hypersensitivity to sennosides or any of the ingredients; appendicitis, intestinal hemorrhage,…