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OXIZOLE® Stiefel Oxiconazole Nitrate Topical Antifungal Action And Clinical Pharmacology: Oxiconazole nitrate is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has fungicidal or fungistatic activity in vitro against a number of pathogenic fungi including the following dermatophytes, and yeasts: T. rubrum, T. mentagrophytes, T. tonsurans, T. violaceum, E. floccosum, M. canis, M. audouini,…

OXSORALEN-ULTRA™ ICN Methoxsalen Melanin Repigmentation – Tolerance Increase to Solar Exposure – Photochemotherapy of Atopic Dermatitis and Psoriasis Indications And Clinical Uses: Repigmentation of idiopathic vitiligo; increasing tolerance to sunlight. Treatment of psoriasis and atopic dermatitis in combination with high intensity UVA light (photochemotherapy). Contra-Indications: Hepatic insufficiency and in those diseases associated with photosensitivity; such as porphyria, acute lupus erythematosus, hydroa and polymorphic light eruptions. In leukoderma of infectious origin…

OTRIVIN® Novartis Consumer Health Xylometazoline HCl Nasal Decongestant Indications And Clinical Uses: Nasal congestion in colds, rhinitis, sinusitis; also for headache, tubal block and serous otitis media associated with nasal congestion. Xylometazoline facilitates rhinoscopy and is a useful pre- and postoperative adjunct. Contra-Indications: Narrow-angle glaucoma. Concurrent therapy with MAO inhibitors. Hypersensitivity to any component. Sensitivity to even small doses of adrenergic substances as manifested by sleeplessness, dizziness, lightheadedness, weakness, tremulousness,…

OXEZE® TURBUHALER® Astra Formoterol Fumarate Dihydrate Bronchodilator Action And Clinical Pharmacology: Pharmacodynamics: Formoterol produces bronchodilation by stimulation of the b2-adrenergic receptors in bronchial smooth muscle, thereby causing relaxation of smooth muscle fibres. Following inhalation of formoterol, a marked improvement in pulmonary function is observed within 1 to 3 minutes and lasts for a mean duration of 12 hours after a single dose. Pharmacokinetics: Absorption: Inhaled formoterol is rapidly absorbed. Peak…

Bionutrix Osteonutrix: Osteonutrix is a specialized Bionutrix herbal preparation designed by physicians at Bionutrix to maximize bone health. In this premium product, Bionutrix has combined four important supplements in this special formulation as they work synergistically together to arrest cartilage deterioration and to rebuild damaged cartilage. Supportive in: Osteoarthritis – decreases pain and increases mobility in people suffering from osteoarthritis Restoring damaged bone joint tissue in osteoarthritis Tendonitis and bursitis…

ORO-CLENSE Germiphene Chlorhexidine Gluconate Antigingivitis Oral Rinse Action And Clinical Pharmacology: Chlorhexidine provides antimicrobial activity during oral rinsing which is maintained between rinsings. Microbiologic sampling of plaque has shown a general reduction of both aerobic and anaerobic bacterial counts through 6 months’ clinical use. Rinsing with chlorhexidine inhibits the build up and maturation of plaque by reducing certain microbes regarded as gingival pathogens, thereby reducing gingivitis. Chlorhexidine provides antimicrobial activity…

OMNIPAQUE® Nycomed Imaging A.S. Iohexol Nonionic Radiographic Contrast Medium Action And Clinical Pharmacology: Immediately following rapid intravascular injection, iohexol reaches peak plasma concentration and is then rapidly distributed throughout the extracellular fluid compartment. Iohexol does not normally cross the blood-brain barrier to any significant extent. It is excreted unchanged by the kidneys, mainly by glomerular filtration; tubular secretion plays a minor role, and a very small quantity (1 to 2%)…

OCUCLEAR® Schering Oxymetazoline HCl Topical Decongestant Action And Clinical Pharmacology: Oxymetazoline elicits relief of conjunctival hyperemia by causing vasoconstriction of superficial conjunctival blood vessels. The drug’s action has been demonstrated in acute allergic conjunctivitis and in chemical (chloride) conjunctivitis. Oxymetazoline has a lesser tendency to dilate the pupils than 0.12% phenylephrine. There are no clinical data available on the degree and rate of systemic absorption of oxymetazoline when used topically…

OCUFLOX™ Allergan Ofloxacin Antibacterial Agent Action And Clinical Pharmacology: The primary mechanism of action of ofloxacin appears to be the specific inhibition of DNA gyrase (topoisomerase II). This enzyme is responsible for the negative supercoiling of bacterial DNA and consequently for its topological configuration, governing functions such as RNA transcription, protein synthesis, DNA replication and repair functions. Indications And Clinical Uses: For the treatment of conjunctivitis when caused by susceptible…

OMNI-TUSS® Rh´ne-Poulenc Rorer Codeine – Chlorpheniramine – Ephedrine – Phenyltoloxamine (Resin Complex) Antitussive – Decongestant – Expectorant Indications And Clinical Uses: To facilitate expectoration and control cough associated with inflamed mucosa and tenacious sputum which does not respond to products of lesser potency. Contra-Indications: Hypertension, cardiac disease, hyper- thyroidism, prostatic hypertrophy, sensitivity to any of the components, patients receiving MAO inhibitors. Precautions: Before prescribing medication to suppress or modify cough,…