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ASACOL® Procter & Gamble Pharmaceuticals 5-ASA Lower Gastrointestinal Anti-inflammatory Action And Clinical Pharmacology: The active ingredient in Asacol, mesalamine (5-aminosalicylic acid, also referred to as 5-ASA), is the major active component of sulfasalazine for the treatment of inflammatory bowel disease. The available evidence suggests that mesalamine has a topical anti-inflammatory effect on the colon, where it inhibits prostaglandin and leukotriene synthesis. Asacol tablets have a special acrylic-based resin coating which…

ARTHROTEC® Searle Diclofenac Sodium – Misoprostol Anti-inflammatory – Analgesic – Mucosal Protective Agent Action And Clinical Pharmacology: Arthrotec is a combination of a nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties and a mucosal protective synthetic analog of prostaglandin E1. Arthrotec has been shown to be as effective as diclofenac in reducing the signs and symptoms of rheumatoid arthritis and osteoarthritis. In addition, Arthrotec has been associated with a lower incidence…

ARISTOCORT® Parenteral Stiefel/Glades Triamcinolone Diacetate Corticosteroid Indications And Clinical Uses: Intralesional Injection: For intralesional or sublesional use in local therapy of various skin diseases, e.g. psoriasis, alopecia areata, neurodermatitis, atopic dermatitis, acne, synovial and sebaceous cysts, pruritus ani, contact and nummular dermatoses. Not for i.v. use. Forte Parenteral: For i.m., intrasynovial or intra-articular injection. Not for i.v. use. May be used in the treatment of asthma, allergies, ulcerative colitis, collagen…

ARISTOCORT® Tablets Stiefel/Glades Triamcinolone Corticosteroid Indications And Clinical Uses: Endocrine Disorders: Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone are the drugs of choice although synthetic analogs may be used in conjunction with mineralocorticoids where applicable; mineralocorticoid supplementation is of particular importance when treating this condition in infants); nonsuppurative thyroiditis; hypercalcemia associated with cancer. Rheumatic Disorders: As adjunctive therapy for short-term administration (to tide the patient over an acute episode…

ARISTOCORT® Topicals Stiefel/Glades Triamcinolone Acetonide Topical Corticosteroid Indications And Clinical Uses: In management of certain dermatoses, e.g., atopic dermatitis, eczematous dermatitis, nummular eczema, contact dermatitis, pruritus vulvae and ani, generalized erythrodermia, external otitis, seborrheic dermatitis, eczematized psoriasis, neurodermatitis. Contra-Indications: Tuberculosis of skin, fungal and viral dermal lesions, herpes simplex, chickenpox and vaccinia. Hypersensitivity to any of the components. Manufacturers’ Warnings In Clinical States: Pregnancy and Lactation: The safety of topical…

AQUATAIN® Whitehall-Robins Emollient Indications And Clinical Uses: Emollient for dry, chapped, rough skin. Dosage: Apply as needed several times daily or as prescribed. Availability And Storage: Cream: Each tube of unscented, hypoallergenic cream contains: benzyl alcohol, polawax, isopropyl palmitate, glycerin, sorbitol, lactic acid and water. Tartrazine-free. Tubes of 75 g. Lotion: Each bottle of unscented, hypoallergenic lotion contains: benzyl alcohol, polawax, isopropyl palmitate, glycerin, sorbitol, lactic acid and water. Tartrazine-free….

AQUASOL® E Novartis Consumer Health Vitamin E Vitamin Action And Clinical Pharmacology: Vitamin E is a fat soluble vitamin which is present in many foods and exists in a variety of forms. It is considered an essential element of human nutrition, with many of its actions related to its antioxidant properties. Indications And Clinical Uses: A nutritional supplement for the treatment of vitamin E deficiency. Vitamin E deficiency states are…

ARALEN® Sanofi Chloroquine Phosphate Antimalarial – Antiparasitic Action And Clinical Pharmacology: Chloroquine has been found to be highly active against the erythrocytic forms of Plasmodium vivax, ovale and malariae and many strains of Plasmodium falciparum (but not the gametocytes of Plasmodium falciparum). The precise mechanism of plasmodicidal action of the drug is not known. While the drug can inhibit certain enzymes, its effect is believed to result, in part, from…

AREDIA® Novartis Pharmaceuticals Pamidronate Disodium Bone Metabolism Regulator Action And Clinical Pharmacology: Pamidronate belongs to a class of bisphosphonates (previously termed diphosphonate), which inhibit bone resorption. The therapeutic activity of pamidronate is attributable to its potent anti-osteoclastic activity on bone. In animal studies, at therapeutic doses, pamidronate inhibits bone resorption apparently without inhibiting bone formation and mineralization. The predominant means by which pamidronate reduces bone turnover both in vitro and…

AQUACORT® Spectropharm Dermatology Hydrocortisone Topical Corticosteroid Action And Clinical Pharmacology: Topical corticosteroids are synthetic derivatives of cortisone which are effective when applied locally to control many types of inflammatory, allergic and pruritic dermatoses. They are thought to act by controlling the rate of synthesis of proteins. The primary action of the corticosteroid is to interfere with the synthesis of arachidonic acid by inhibiting the phospholipase A2 synthesis. The overall effect…