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BARBITURATES Amobarbital Butabarbital Pentobarbital Phenobarbital Secobarbital Anticonvulsant – Sedative-Hypnotic Pharmacology: Barbiturates are nonselective central nervous system (CNS) depressants, capable of producing all degrees of depression from mild sedation and hypnosis to general anaesthesia, deep coma and death. The extent of CNS depression varies with the route of administration, dose and pharmacokinetic characteristics of the particular barbiturate. Patient specific factors such as age, physical or emotional state and the concomitant use…

BARRIERE-HC® Roberts Hydrocortisone – Silicone Dermatitis Therapy Indications And Clinical Uses: Adjunctive treatment of allergic dermatoses and other inflammatory skin conditions amenable to topical corticosteroid therapy (e.g., contact, atopic and seborrheic dermatitis, neurodermatitis, psoriasis and anogenital pruritus). Contra-Indications: Tuberculous and most fungal and viral lesions of the skin, herpes simplex, vaccinia and varicella particularly. Precautions: Although untoward effects associated with the use of topical corticosteroids are uncommon and not to…

BAYCOL® Bayer Cerivastatin Sodium Lipid Metabolism Regulator Action And Clinical Pharmacology: Cerivastatin is an entirely synthetic, enantiomerically pure cholesterol-lowering agent and is structurally similar to the fungal derivatives of this therapeutic class. Cerivastatin is a competitive inhibitor of 3-hydroxy-3methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. The inhibition of cholesterol biosynthesis by cerivastatin…

BCG Vaccine (Freeze Dried) Connaught Attenuated Tubercle Bacillus Active Immunizing Agent Action And Clinical Pharmacology: BCG Vaccine (Freeze-Dried) for intracutaneous administration, as prepared by Connaught Laboratories Limited, is made from a culture of an attenuated strain of living bovine tubercle bacillus (Bacillus Calmette-Gurin). It is supplied as a freeze-dried product ready for immediate use following reconstitution with the accompanying diluent, which consists of sterile phosphate-buffered saline. The manufacturing and testing…

BACITRACIN Pharmacia & Upjohn Antibiotic Action And Clinical Pharmacology: Bacitracin, an antibiotic substance derived from cultures of B. subtilis (Tracey), exerts pronounced antibacterial action in vitro against a variety of gram-positive and a few gram-negative organisms. However, among systemic diseases, only staphylococcal infections qualify for consideration of bacitracin therapy. Bacitracin is assayed against a standard and its activity is expressed in units, 1 mg having a potency of not less…

BABY’S OWN™ INFANT DROPS Block Drug Simethicone Antiflatulent Indications And Clinical Uses: To relieve infant colic, bloating and flatulence due to gas. Warnings: Keep this and all drugs out of the reach of children. Do not take for more than 2 weeks unless directed by a physician. If symptoms recur consult a physician. Dosage: Shake well before using. Use only on the advice of a physician. Infants (under 2 years):…

BACID® Rh´ne-Poulenc Rorer Lactobacillus acidophilus Flora Modifier Indications And Clinical Uses: To assist in the restoration and maintenance of the normal physiological and bacterial flora of the oral and intestinal tracts. Has been used in the prevention and treatment of postantibiotic stomatitis and microbial diarrheas; also in aphthous and herpetic stomatitis. Precautions: Should be stored in a refrigerator at a temperature of 10°C, or below to maintain potency. Not to…

BACIGUENT® Johnson & Johnson• Merck Bacitracin Topical Antibiotic Indications And Clinical Uses: For the treatment and prevention of infection in minor cuts, wounds and burns. Manufacturers’ Warnings In Clinical States: For external use only. Avoid contact with eyes. If contact occurs, wash thoroughly with water. Use should be discontinued if condition worsens. No refrigeration required. Precautions: Discontinue if sensitization occurs. Prolonged use may result in the overgrowth of nonsusceptible organisms,…

ASASANTINE® Boehringer Ingelheim Dipyridamole – ASA Inhibitor of Platelet Adhesion and Aggregation Action And Clinical Pharmacology: The combined use of dipyridamole and ASA causes a significant reduction in the incidence of new fatal and nonfatal coronary events in patients with a previously documented myocardial infarction. In a randomized, double blind study, the effects of combined dipyridamole and ASA treatment were compared to ASA alone and to placebo in 2 026…

ARLIDIN® ARLIDIN® FORTE Rhône-Poulenc Rorer Nylidrin HCl Peripheral Vasodilator – Organic Brain Syndrome Therapy Action And Clinical Pharmacology: Nylidrin acts predominantly by beta receptor stimulation. It has been shown to dilate arterioles in skeletal muscle and to increase cardiac output. An increase in cerebral blood flow and a decrease in vascular resistance has also been reported. The result of this combination of actions is a greater blood supply to ischemic…