Indications And Clinical Uses: In management of certain dermatoses, e.g., atopic dermatitis, eczematous dermatitis, nummular eczema, contact dermatitis, pruritus vulvae and ani, generalized erythrodermia, external otitis, seborrheic dermatitis, eczematized psoriasis, neurodermatitis.
Contra-Indications: Tuberculosis of skin, fungal and viral dermal lesions, herpes simplex, chickenpox and vaccinia. Hypersensitivity to any of the components.
Manufacturers’ Warnings In Clinical States: Pregnancy and Lactation: The safety of topical corticosteroids during pregnancy and lactation has not been established. The potential benefit of topical corticosteroids, if used during pregnancy and lactation, should be weighed against possible hazard to the fetus or the nursing infant.
If used under an occlusive dressing, particularly over extensive areas, sufficient absorption may take place to give rise to adrenal suppression and other systemic effects.
Topical corticosteroids are not for ophthalmic use.
Precautions: Should not be used in the eyes. Although untoward effects associated with the use of topical corticosteroids are uncommon and not to be expected from ordinary use, sensitization, irritation and failure of therapeutic response have been noted in rare instances. Application to extensive areas, too frequent application, or application under occlusive dressings may result in systemic absorption with symptoms of adrenal suppression, localized atrophy and striae. If infection of the tissues is present, the use of a systemic broad spectrum antibiotic may be desirable.
Pregnancy: While topical corticosteroids have not been reported to have an adverse effect on pregnancy, the safety of their use on pregnant females, has not absolutely been established. Therefore, they should not be used extensively on pregnant patients, in large amounts or for prolonged periods of time.
Adverse Reactions: The following local adverse reactions have been reported rarely with the use of topical corticosteroids: burning, itching, irritation, dryness, folliculitis, hypertrichosis, hypopigmentation.
The following may occur more frequently with occlusive dressings: maceration of the skin, secondary infection, skin atrophy, striae, miliaria, pustules, pyoderma.
Dosage: Apply in small quantities to the affected areas 3 or 4 times daily. Some cases of psoriasis and certain other refractory dermatoses may be treated more effectively by the application of triamcinolone acetonide topicals under an occlusive nonpermeable dressing such as Saran Wrap.
Availability And Storage: Cream: Aristocort “C” (0.5%), concentrate, 15 g tubes; Aristocort “R” (0.1%), regular, 30 g tubes and 500 g jars; Aristocort “D” (0.025%) dilute, 30 g tubes. Nonmedicinal ingredients: benzyl alcohol, emulsifying wax, glycerin, isopropyl palmitate, lactic acid, sorbitol solution and water purified.
Ointment: Aristocort “R” (0.1%) regular, 30 g tubes. No preservatives. Nonmedicinal ingredients: white petrolatum.
ARISTOCORT® Topicals Stiefel/Glades Triamcinolone Acetonide Topical Corticosteroid
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