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BETADINE® Topical Preparations Purdue Frederick Povidone-Iodine Antiseptic Action And Clinical Pharmacology: Betadine is iodine complexed with povidone (polyvinyl-pyrrolidone). The compound is soluble in water forming a golden brown solution. Like iodine, the solution of the iodine complex is bactericidal, fungicidal, virucidal and trichomonacidal. However, unlike solutions of iodine, it is non-staining to natural fabrics. The antiseptic action of povidone-iodine is due to the available iodine present in the complex. Indications…

BETADINE® Vaginal Preparations Purdue Frederick Povidone-Iodine Bactericidal – Trichomonacidal – Fungicidal Action And Clinical Pharmacology: Betadine is iodine complexed with povidone (polyvinyl-pyrrolidone). The compound is soluble in water forming a golden brown solution. Like iodine, the solution of the iodine complex is bactericidal, trichomonacidal, fungicidal and virucidal. Unlike solutions of iodine it is nonstaining to skin and natural fabrics. The antiseptic action is due to the available iodine present in…

BETAGAN® Allergan Levobunolol HCl Glaucoma Therapy Action And Clinical Pharmacology: Levobunolol is a noncardioselective beta- adrenoceptor antagonist, equipotent at both beta1 and beta2 receptors. Levobunolol is approximately 60 times more potent than the dextro isomer in its beta-blocking activity, yet equipotent in its potential for direct myocardial depression. Accordingly, the levo isomer, levobunolol, is used. Levobunolol does not have significant local anesthetic (membrane-stabilizing) effect or intrinsic sympathomimetic activity. Beta-adrenergic receptor…

BENZTROPINE MESYLATE Antiparkinsonian Agent Pharmacology: Benztropine is a synthetic tertiary amine with structural similarities to atropine and diphenhydramine. Benztropine exhibits anticholinergic, antihistaminic and local anesthetic properties. Its mechanism of action as an antiparkinsonian agent is not clearly known. The pharmacologic effects of the drug may not be apparent until 2 to 3 days after initiation of therapy and may persist for up to 24 hours after discontinuation of the drug….

BEROTEC® Inhalation Aerosol BEROTEC® FORTE Inhalation Aerosol Boehringer Ingelheim Fenoterol HBr Bronchodilator Action And Clinical Pharmacology: The bronchodilating effect of fenoterol is produced primarily by stimulation of b2 receptors in the bronchial smooth muscles. The effect has been measured by means of spirometry (FEV1, FVC, MMFR), peak flow rates, flow volume curves, airway resistance (plethysmography) and oscillation mechanics. Fenoterol, when administered by inhalation, exerts a significant increase in pulmonary function…

BEROTEC® Inhalation Aerosol BEROTEC® FORTE Inhalation Aerosol Boehringer Ingelheim Fenoterol HBr Bronchodilator Action And Clinical Pharmacology: The bronchodilating effect of fenoterol is produced primarily by stimulation of b2 receptors in the bronchial smooth muscles. The effect has been measured by means of spirometry (FEV1, FVC, MMFR), peak flow rates, flow volume curves, airway resistance (plethysmography) and oscillation mechanics. Fenoterol, when administered by inhalation, exerts a significant increase in pulmonary function…

BEROTEC® Inhalation Solution Boehringer Ingelheim Fenoterol HBr Bronchodilator Action And Clinical Pharmacology: The bronchodilating effect of fenoterol is produced primarily by stimulation of b2-receptors in the bronchial smooth muscles. The effect has been measured by means of spirometry (FEV1, FVC, MMFR), peak flow rates, flow volume curves, airway resistance (plethysmography) and oscillation mechanics. Fenoterol, when administered by inhalation, exerts a significant increase in pulmonary function 5 minutes after administration and…

BENTYLOL® Hoechst Marion Roussel Dicyclomine HCl Antispasmodic Action And Clinical Pharmacology: Dicyclomine relieves smooth muscle spasm of the gastrointestinal tract. Animal studies indicate that this action is achieved via a dual mechanism: 1) a specific anticholinergic effect (antimuscarinic) at the ACh-receptor sites with approximately 1/8 the mg potency of atropine (in vitro guinea pig ileum); 2) a direct effect upon smooth muscle (musculotropic) as evidenced by dicyclomine’s antagonism of bradykinin-…

BENZAMYCIN® Dermik Laboratories Canada Erythromycin – Benzoyl Peroxide Acne Therapy Action And Clinical Pharmacology: Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration…

BENZODIAZEPINES Alprazolam Bromazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Diazepam Flurazepam Lorazepam Midazolam Nitrazepam Oxazepam Temazepam Triazolam Anticonvulsant – Anxiolytic – Hypnotic – Sedative Action And Clinical Pharmacology: Benzodiazepines are glycoproteins with an affinity for benzodiazepine receptors which act as specific binding sites for gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the CNS. Although various mechanisms of action have been proposed, the precise sites and mechanisms of action have not…