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COTAZYM® Organon Pancrelipase Preparations Enzymes – Digestant Indications And Clinical Uses: Pancreatic enzyme replacement therapy in established pancreatic insufficiency where pancreatic enzymes are absent from or present in insufficient amount in the intestine: pancreatectomy, chronic pancreatitis, cystic fibrosis, steatorrhea and other malabsorption syndromes in which fat digestion is inadequate because of deficiency of pancreatic enzymes. Contra-Indications: Allergy to porcine protein. Manufacturers’ Warnings In Clinical States: In the event that capsules…

COUMADIN® DuPont Pharma Warfarin Sodium Anticoagulant Action And Clinical Pharmacology: Warfarin and other coumarin anticoagulants act by inhibiting the synthesis of vitamin K dependent clotting factors, which include Factors II, VII, IX and X, and the anticoagulant proteins C and S. Half-lives of these clotting factors are as follows: Factor II – 60 hours, VII – 4 to 6 hours, IX – 24 hours, and X – 48 to 72…

CORTONE® Suspension MSD Cortisone Acetate Corticosteroid Action And Clinical Pharmacology: Cortisone is a natural product of the adrenal cortex. Cortisone is a synthetic steroid with the basic actions and effects of other glucocorticoids. Cortisone sterile suspension has a slow onset but long duration of action when compared with more soluble preparations. When daily corticosteroid therapy is required and oral therapy is not feasible, the required daily dosage may be given…

CORTONE® Tablets MSD Cortisone Acetate Corticosteroid Action And Clinical Pharmacology: Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Cortisone is a natural product of the adrenal cortex. Cortisone acetate is a synthetic steroid with the basic actions and effects of other glucocorticoids. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency…

CORTATE® 0.5 % CORTATE® 1 % Schering Hydrocortisone Topical Corticosteroid Indications And Clinical Uses: For temporary relief of minor skin irritations, itching and rashes due to eczema, dermatitis, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics and jewellery. Manufacturers’ Warnings In Clinical States: For external use only. Do not use in or around the eyes. Do not apply to large areas of the body. Do not use…

CORTEF® Pharmacia & Upjohn Hydrocortisone Corticosteroid Action And Clinical Pharmacology: Hydrocortisone (cortisol) is a corticosteroid secreted by the adrenal cortex. In physiologic doses, it is administered to replace deficient endogenous hormones. In larger (pharmacologic) doses, hydrocortisone decreases inflammation and suppresses the immune response. It stimulates erythroid cells of the bone marrow, prolongs survival time of erythrocytes and platelets, and produces neutrophilia and eosinopenia. Hydrocortisone promotes protein catabolism, gluconeogenesis, and redistribution…

CORTIFOAM™ R & C Hydrocortisone Acetate Rectal Anti-inflammatory Action And Clinical Pharmacology: Action appears to be due to a local anti-inflammatory effect of hydrocortisone on the mucosa rather than as a result of a systemic effect. Indications And Clinical Uses: As adjunctive therapy in the treatment of ulcerative colitis of the sigmoid colon, proctosigmoiditis, granular proctitis and ulcerative proctitis. Contra-Indications: To the use of intrarectal steroids include, obstruction, abscess, perforation,…

CORTENEMA® Axcan Pharma Hydrocortisone Glucocorticoid Indications And Clinical Uses: An adjunct in the treatment of nonspecific inflammatory diseases involving the rectum, sigmoid and left colon such as idiopathic ulcerative colitis, ulcerative proctitis, regional enteritis (granulomatous colitis) with left side involvement, proctitis, proctocolitis, and radiation proctitis. Contra-Indications: Local contraindications to the use of intrarectal steroids include obstruction, abscess, perforation, peritonitis, fresh intestinal anastomoses, extensive fistulas and sinus tracts. Active tuberculosis (active,…

BRONKAID® MISTOMETER® Sanofi Epinephrine Bronchodilator Action And Clinical Pharmacology: Epinephrine is a sympathomimetic drug that acts on both alpha and beta receptors. Indications: For temporary relief of acute paroxysms of bronchial asthma. Manufacturers’ Warnings In Clinical States: For oral inhalation only. Do not use this product unless a diagnosis of asthma has been made by a physician, if you have heart disease, high blood pressure, thyroid disease, diabetes, or difficulty…

BUSPAR® Bristol Buspirone HCl Anxiolytic Action And Clinical Pharmacology: Buspirone is a psychotropic drug with selective anxiolytic properties which belongs chemically to the class of compounds known as the azaspirodecanediones, not chemically or pharmacologically related to benzodiazepines. Buspirone shares some of the properties of the benzodiazepines and the neuroleptics, as well as demonstrating other pharmacological action. Buspirone attenuates punishment suppressed behavior in animals and exerts a taming effect, but is…