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NADOSTINE® Preparations Nadeau Nystatin Antifungal – Antibiotic Indications And Clinical Uses: Oral Suspension: Prevention and treatment of candidal infections of the mouth (thrush) and intestinal candidiasis in infants and children. Oral Tablets: Prevention and treatment of oral, esophageal and intestinal candidiasis. Protection against candidal overgrowth during antibiotic and/or corticosteroid therapy. Topical Products: Treatment of mucocutaneous candidiasis. The cream is usually used to treat intertriginous areas. Vaginal Products: Local treatment of…

NADOPEN-V® Nadeau Penicillin V Potassium Antibiotic Indications And Clinical Uses: Mild to moderately severe infections caused by penicillin V sensitive microorganisms including streptococcal pharyngitis, staphylococcal infection without bacteremia and pneumococcal infections. Therapy should be guided by bacteriologic sensitivity tests and clinical response. For prophylaxis following rheumatic fever and/or chorea. (Prophylaxis with oral penicillin on a continuing basis has proved effective in preventing recurrences of these conditions.) To prevent bacterial endocarditis…

MUSTARGEN® MSD Mechlorethamine HCl Alkylating Agent Action And Clinical Pharmacology: Mechlorethamine, a biologic alkylating agent, has a cytotoxic action which inhibits rapidly proliferating cells. tag_IndicationsIndications Indications And Clinical Uses: Before using mechlorethamine see Contraindications, Warnings, Precautions, Adverse Effects and Dosage. Administered i.v., mechlorethamine is indicated for the palliative treatment of Hodgkin’s disease (Stages III and IV), lymphosarcoma, chronic myelocytic or chronic lymphocytic leukemia, polycythemia vera, mycosis fungoides and bronchogenic carcinoma….

MUTACOL BERNA® Berna Products Cholera Vaccine Live Oral CVD 103-HgR Cholera Prophylaxis Action And Clinical Pharmacology: V. cholerae is the etiological agent of cholera, an acute diarrheal disease. This vaccine will not afford protection against species of vibrio other than 01 V. cholerae or against other bacteria that cause enteric disease. Mutacol Berna vaccine will not afford protection against 0139 V. cholerae. There are less than 30 cases of cholera…

MUTAMYCIN® Bristol Mitomycin Antineoplastic Action And Clinical Pharmacology: Mitomycin was investigated at first as an antibiotic in Japan. It was then found to be active as an antineoplastic agent. It selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The exact point of mitomycin attachment to DNA remains unknown. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed. Mitomycin is rapidly cleared from the plasma after…

MSD® ENTERIC COATED ASA Johnson & Johnson Merck ASA Nonsteroidal Anti-inflammatory – Analgesic – Platelet Aggregation Inhibitor Action And Clinical Pharmacology: ASA has analgesic, antipyretic and anti-inflammatory properties. In rheumatic diseases, although the analgesic and antipyretic effects are useful, the major purpose for which ASA is used is to reduce the intensity of the inflammatory process. Inhibition of prostaglandin synthesis may be involved in the anti-inflammatory action of ASA. ASA…

MULTITEST® CMI Connaught Skin Test Antigens for Cell-Mediated Immunity Diagnostic Aid Action And Clinical Pharmacology: The delayed cutaneous responses associated with the ubiquitous antigens in the Multitest battery appear to be typical cellular hypersensitivity reactions. A relatively small amount of soluble antigen is introduced into the epidermia and superficial dermal tissue by puncture. Circulating T-cells (lymphocytes), sensitized to the antigen from prior contact, react with the antigens in the skin…

MUCOMYST® Roberts Acetylcysteine Mucolytic – Antidote for Acetaminophen Poisoning Action And Clinical Pharmacology: The viscosity of pulmonary mucous secretions depends on the concentrations of mucoprotein and to a lesser extent deoxyribonucleic acid (DNA). The latter increases with increasing purulence owing to cellular debris. The mucolytic action of acetylcysteine is related to the sulfhydryl group in the molecule. This group probably “opens” disulfide linkages in mucus thereby lowering the viscosity. The…

MOTRIN® IB McNeil Consumer Products Ibuprofen Analgesic – Antipyretic – Anti-inflammatory Action And Clinical Pharmacology: Ibuprofen is a member of the class of agents commonly known as nonsteroidal anti-inflammatory drugs (NSAIDs). Consistent with this classification, ibuprofen exhibits anti-inflammatory activity at higher dosage ranges. At lower adult single doses relevant to a 200 mg dosage strength (200 to 400 mg) ibuprofen relieves pain of mild to moderate intensity and reduces fever….

MOTRIN® Pharmacia & Upjohn Ibuprofen Anti-inflammatory – Analgesic – Antipyretic Action And Clinical Pharmacology: Ibuprofen has demonstrated anti-inflammatory, analgesic and antipyretic activity in animal studies designed to specifically demonstrate these effects. Its mode of action, like that of other nonsteroidal anti-inflammatory agents, is not completely understood, but may be related to prostaglandin synthetase inhibition. Ibuprofen does not alter the course of the underlying disease. Ibuprofen has no demonstrable glucocorticoid effect….