You searched for : 'U'

NEUPOGEN® Amgen Filgrastim Granulocyte Colony Stimulating Factor – Hematopoietic Agent Action And Clinical Pharmacology: Filgrastim is a human granulocyte colony stimulating factor (G-CSF) produced by recombinant DNA technology. G-CSF regulates the production of neutrophils within the bone marrow; endogenous G-CSF is a glycoprotein produced by monocytes, fibroblasts, and endothelial cells. G-CSF is a colony stimulating factor which has been shown to have minimal direct in vivo or in vitro effects…

NEULEPTIL® Rhône-Poulenc Rorer Pericyazine Psychotropic Agent Action And Clinical Pharmacology: Pericyazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine effects, and an action on the extrapyramidal system. Like other…

NERISALIC® Stiefel Diflucortolone Valerate – Salicylic Acid Topical Corticosteroid – Keratolytic Action And Clinical Pharmacology: Nerisalic combines the anti-inflammatory, antipruritic and vasoconstrictive activity of diflucortolone valerate and the keratolytic effects of salicylic acid. Both diflucortolone valerate and its split ester are topically active. Indications And Clinical Uses: The topical treatment of chronic eczema, psoriasis vulgaris, neuro-dermatitis and scaly crusty dermatoses which respond to corticosteroid therapy. Nerisalic is not suitable for…

NEBCIN® Lilly Tobramycin Sulfate Antibiotic Action And Clinical Pharmacology: Like other aminoglycosides, the bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria, but at the present time, very little is known about this action. It is thought that inhibition of synthesis is due to an action on ribosomes that, in turn, causes bacterial misreading of messenger RNA. Peak serum concentrations of tobramycin occur…

NALCROM® Rhône-Poulenc Rorer Sodium Cromoglycate Antiallergic Agent Action And Clinical Pharmacology: Sodium cromoglycate seems to exert a stabilizing effect upon mast cells capable of releasing mediators. In gastrointestinal disease, the release of mediators causes a local inflammation which can either result in gastrointestinal symptoms or may allow absorption of antigenic material leading to systemic allergic reactions. It is most effective when given prior to antigen challenge. Sodium cromoglycate has no…

NALFON® Lilly Fenoprofen Calcium Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Fenoprofen has demonstrated anti-inflammatory, analgesic and antipyretic activities in animal studies. Although fenoprofen’s modes of action are unknown, in vitro tests have shown that it inhibits synthesis and/or release of prostaglandins; stabilizes lysosomes; inhibits platelet aggregation and platelet adhesiveness, and enhances fibrinolytic activity. All of these activities may have a role in the amelioration of inflammation, pain and fever….

MYCIFRADIN® Pharmacia & Upjohn Neomycin Sulfate Antibiotic Action And Clinical Pharmacology: Neomycin is an aminoglycoside antibiotic, active against many strains of Gram-negative bacteria. Neomycin is poorly absorbed from the normal gastrointestinal tract. The small absorbed fraction is rapidly distributed in the tissues and is excreted by the kidney in keeping with the degree of kidney function. The unabsorbed portion of the drug (approximately 97%) is eliminated unchanged in the feces….

NADOPEN-V® Nadeau Penicillin V Potassium Antibiotic Indications And Clinical Uses: Mild to moderately severe infections caused by penicillin V sensitive microorganisms including streptococcal pharyngitis, staphylococcal infection without bacteremia and pneumococcal infections. Therapy should be guided by bacteriologic sensitivity tests and clinical response. For prophylaxis following rheumatic fever and/or chorea. (Prophylaxis with oral penicillin on a continuing basis has proved effective in preventing recurrences of these conditions.) To prevent bacterial endocarditis…

MUMPSVAX® MSD Mumps Virus Vaccine, Live, Attenuated Mumps Prophylaxis Description: This vaccine is prepared from the Jeryl Lynn (B Level) strain, named after the patient from whom the virus was initially recovered. Mumpsvax is a sterile lyophilized preparation of the Jeryl Lynn (B level) strain of mumps virus. The virus was adapted to and propagated in cell cultures of chick embryo, free of avian leukosis, virus and other adventitious agents…

MUSTARGEN® MSD Mechlorethamine HCl Alkylating Agent Action And Clinical Pharmacology: Mechlorethamine, a biologic alkylating agent, has a cytotoxic action which inhibits rapidly proliferating cells. tag_IndicationsIndications Indications And Clinical Uses: Before using mechlorethamine see Contraindications, Warnings, Precautions, Adverse Effects and Dosage. Administered i.v., mechlorethamine is indicated for the palliative treatment of Hodgkin’s disease (Stages III and IV), lymphosarcoma, chronic myelocytic or chronic lymphocytic leukemia, polycythemia vera, mycosis fungoides and bronchogenic carcinoma….