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OXSORALEN-ULTRA™ ICN Methoxsalen Melanin Repigmentation – Tolerance Increase to Solar Exposure – Photochemotherapy of Atopic Dermatitis and Psoriasis Indications And Clinical Uses: Repigmentation of idiopathic vitiligo; increasing tolerance to sunlight. Treatment of psoriasis and atopic dermatitis in combination with high intensity UVA light (photochemotherapy). Contra-Indications: Hepatic insufficiency and in those diseases associated with photosensitivity; such as porphyria, acute lupus erythematosus, hydroa and polymorphic light eruptions. In leukoderma of infectious origin…

ORUDIS® ORUDIS® E ORUDIS® SR Rhône-Poulenc Rorer Ketoprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Animal pharmacological studies have shown that ketoprofen is a NSAID that possesses anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory action is not mediated through the pituitary adrenal axis. Its therapeutic effectiveness has been demonstrated by a reduction in joint swelling, pain and duration of morning stiffness, and by increased grip strength and an improvement in…

ORUVAIL® May & Baker Pharma Ketoprofen Anti-inflammatory – Analgesic Action And Clinical Pharmacology: Animal pharmacological studies have shown that ketoprofen possesses anti-inflammatory, analgesic and antipyretic properties. The anti-inflammatory action is not mediated through the pituitary adrenal axis. Its therapeutic effectiveness has been demonstrated by a reduction in joint swelling, pain and duration of morning stiffness, and by increased grip strength and an improvement in functional capacity. Clinical trials in patients…

OSTAC® Roche Clodronate Disodium Bone Metabolism Regulator Action And Clinical Pharmacology: Clodronate belongs to the class of bisphosphonates which act primarily on bone. This tissue specificity is due to the high affinity of bisphosphonates for calcium phosphate crystals. Clodronate forms complexes with the hydroxyapatite of bone, altering the crystalline structure in such a way that dissolution of the crystals is inhibited. The major effect of clodronate is to inhibit osteoclast-mediated…

Bionutrix Osteonutrix: Osteonutrix is a specialized Bionutrix herbal preparation designed by physicians at Bionutrix to maximize bone health. In this premium product, Bionutrix has combined four important supplements in this special formulation as they work synergistically together to arrest cartilage deterioration and to rebuild damaged cartilage. Supportive in: Osteoarthritis – decreases pain and increases mobility in people suffering from osteoarthritis Restoring damaged bone joint tissue in osteoarthritis Tendonitis and bursitis…

ORTHOCLONE OKT® 3 Janssen-Ortho Muromonab-CD3 Immunosuppressant Action And Clinical Pharmacology: Muromonab-CD3 sterile solution is a murine monoclonal antibody to the T3 (CD3) antigen of human T cells which functions as an immunosuppressant. It is for i.v. use only. The antibody is a biochemically purified IgG2a immunoglobulin with a heavy chain of approximately 50 000 daltons and a light chain of approximately 25 000 daltons. It is directed to a glycoprotein…

ORTHO-NOVUM® 1/50 Janssen-Ortho Norethindrone – Mestranol Oral Contraceptive Action And Clinical Pharmacology: Acts through the mechanism of gonadotropin suppression primarily at the pituitary-ovarian axis with secondary pelvic involvement. Conception Control: The contraceptive efficacy is attributed to suppression of ovulation with a possible contribution from alterations in cervical mucus and in the endometrium. Amenorrhea: Where normal cycling does not occur, as in amenorrhea, the temporary cyclic administration of Ortho-Novum 1/50 Tablets,…

ORO-CLENSE Germiphene Chlorhexidine Gluconate Antigingivitis Oral Rinse Action And Clinical Pharmacology: Chlorhexidine provides antimicrobial activity during oral rinsing which is maintained between rinsings. Microbiologic sampling of plaque has shown a general reduction of both aerobic and anaerobic bacterial counts through 6 months’ clinical use. Rinsing with chlorhexidine inhibits the build up and maturation of plaque by reducing certain microbes regarded as gingival pathogens, thereby reducing gingivitis. Chlorhexidine provides antimicrobial activity…

ORAMORPH SR™ Boehringer Ingelheim Morphine Sulfate Narcotic Analgesic Action And Clinical Pharmacology: Morphine is a narcotic analgesic which acts as an agonist at stereospecific and saturable opioid receptors in the CNS and other tissues. In man, morphine produces a variety of effects including analgesia, sedation, changes in mood including euphoria and dysphoria, mental clouding, respiratory depression from reduced responsiveness of the brain stem respiratory centres to CO2, suppression of the…

ORASCAN™ Germiphene Toluidine Blue O Oral Cancer Diagnostic System Indications And Clinical Uses: As an oral cancer diagnostic and to establish borders for biopsy and surgical site selection. Precautions: Any use of OraScan must be done after a visual inspection of the oral cavity, and before any instrumentation of soft tissues. OraScan should be used after a complete head and neck cancer exam. Two types of lesions will stain: squamous…