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TAPAZOLE® Lilly Methimazole Antithyroid Action And Clinical Pharmacology: Methimazole inhibits the synthesis of thyroid hormones and thus is effective in the treatment of hyperthyroidism. The drug does not inactivate existing thyroxine and triiodothyronine that are stored in colloid or are circulating in the blood, nor does it interfere with the effectiveness of thyroid hormones given by mouth or by injection. The actions and use of methimazole are similar to those…

TALWIN® Injection Sanofi Pentazocine Lactate Analgesic Action And Clinical Pharmacology: Analgesic effects: Pentazocine relieves pain of all degrees, from mild to severe, in patients with acute and chronic disorders, regardless of age or sex. Analgesia usually occurs within 15 to 30 minutes after i.m. or s.c. injection, or 2 to 3 minutes after i.v. injection, and lasts for 3 to 4 hours. A dose of 30 mg administered parenterally is…

TAMBOCOR™ 3M Pharmaceuticals Flecainide Acetate Antiarrhythmic Agent Action And Clinical Pharmacology: Flecainide belongs to the membrane stabilizing group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the 1C class of the modified Vaughan-Williams classification. It also possesses local anesthetic properties. In single cell preparations from canine cardiac tissue (Purkinje fibres) flecainide decreased the rate of rise (Vmax, Phase O) of the action potential without greatly affecting its duration; the…

T-STAT® Westwood-Squibb Erythromycin – Ethyl Alcohol Topical Anti-acne Therapy Action And Clinical Pharmacology: Ethyl alcohol is a drying and peeling agent. The mechanism of action of topically applied erythromycin in the treatment of acne vulgaris is not known. Indications And Clinical Uses: For the treatment of the inflammatory papular lesions of acne vulgaris. Not indicated for Grade IV acne. Contra-Indications: Individuals who have shown hypersensitivity to erythromycin or any of…

TAGAMET® SmithKline Beecham Cimetidine Histamine H2 Receptor Antagonist Action And Clinical Pharmacology: Cimetidine competitively inhibits the action of histamine at the histamine H2 receptor and thus represents a new class of pharmacological agents, the histamine H2 receptor antagonists. Cimetidine is not an anticholingeric agent. Studies have shown that cimetidine inhibits both daytime and nocturnal basal gastric acid secretion. Cimetidine also inhibits gastric acid secretion stimulated by food, histamine, pentagastrin, caffeine…

TALWIN® Tablets Sanofi Pentazocine HCl Analgesic Action And Clinical Pharmacology: Pentazocine is a member of the benzazocine series of synthetic benzomorphans. It produces both analgesic (agonist) and narcotic antagonist effects. The analgesic effect of 50 mg pentazocine administered orally is approximately equivalent to 60 mg codeine. Pentazocine also produces a sedative effect. The onset of analgesia following oral administration of pentazocine can occur within 15 to 30 minutes and the…

TYLENOL® COUGH MEDICATION McNeil Consumer Healthcare Acetaminophen-Dextromethorphan HBR Analgesic-Antipyretic-Antitussive Indications And Clinical Uses: For the temporary relief of dry cough, sore throat, aches, pains and fever. Contra-Indications: Known hypersensitivity to acetaminophen and/or pressor amines. Patients receiving or having received MAO inhibitors in the preceding 2 weeks. Although pseudoephedrine is virtually without pressor effect in normotensive patients, it should be used with caution in hypertensive individuals.: Precautions: As with any other…

TYLENOL® FLU MEDICATION McNeil Consumer Healthcare Acetaminophen-Pseudoephedrine HCl Compound Analgesic-Antipyretic-Antihistamine-Antitussive-Decongestant Preparations Indications And Clinical Uses: For the temporary relief of runny nose, sneezing, watery and itchy eyes, nasal congestion, aches, pain and fever due to flu. Contra-Indications: Known hypersensitivity to acetaminophen, pressor amines or other individual ingredients. Patients receiving or having received MAO inhibitors in the preceding 2 weeks. Although pseudoephedrine is virtually without pressor effect in normotensive patients, it should…

TYLENOL® SINUS MEDICATION McNeil Consumer Healthcare Acetaminophen-Pseudoephedrine HCl Analgesic-Decongestant Indications And Clinical Uses: For the temporary relief of sinus headache pain and congestion caused by sinusitis and common colds. Contra-Indications: Known hypersensitivity to acetaminophen and/or pressor amines. Patients receiving or having received MAO inhibitors in the preceding 2 weeks. Although pseudoephedrine is virtually without pressor effect in normotensive patients, it should be used with caution in hypertensives. Precautions: As with…

TYPHIM Vi™ Connaught Salmonella Typhi Vi Capsular Polysaccharide Vaccine Active Immunizing Agent Action and Clinical Pharmacology: PharmacologyS. typhi is the etiological agent of typhoid fever, an acute, febrile enteric disease transmitted by contaminated water and food. The fatality rate ranges from 16% in untreated cases to less than 1% in those given appropriate antibiotic therapy. The incidence of typhoid fever has declined steadily in Canada. Approximately 80 cases are reported…