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TOLECTIN® Janssen-Ortho Tolmetin Sodium Anti-inflammatory–Analgesic–Antipyretic Action and Clinical Tolmetin has demonstrated anti-inflammatory, analgesic and antipyretic properties in classical animal test systems. In patients with rheumatoid arthritis, the anti-inflammatory action has been shown by a reduction in joint swelling, pain and duration of morning stiffness, as well as by enhanced grip strength, increased mobility and increased delay in the onset of fatigue. Studies in laboratory animals and man have demonstrated that…

TOLEREX® Novartis Nutrition Elemental Diet Indications And Clinical Uses: A nutritionally complete elemental diet formulated for the nutritional management of patients with impaired digestion and absorption. May include those with inflammatory bowel disease, intestinal atresia, pancreatitis, fistula, partial obstruction, short-gut syndrome. Malnutrition and cachexia. Bowel preparation prior to diagnostic and surgical procedures. Transition diet between parenteral and normal oral feeding. Food sensitivities.: Precautions: Not for parenteral administration. For use only…

TOMYCINE™ CIBA Vision Tobramycin Topical Antibiotic Availability And Storage: Each mL of sterile ophthalmic solution contains: tobramycin 0.3% (3 mg/mL). Nonmedicinal ingredients: benzalkonium chloride (preservative), boric acid, purified water, sodium chloride, sodium hydroxide and/or sulfuric acid (to adjust pH), sodium sulfate and tyloxapol. Plastic squeeze bottles of 5 mL. Avoid contamination of the dropper tip by avoiding contact with the eye, skin or other surfaces. Keep this bottle tightly closed…

TOBREX® Alcon Tobramycin Topical Antibiotic Action and Clinical Like other aminoglycosides, the bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria, but at the present time, very little is known about this action. It is thought that inhibition of synthesis is due to an action on ribosomes that, in turn, causes bacterial misreading of messenger RNA. Because the ocular concentrations of tobramycin achieved…

TOBRAMYCIN Rivex Ophthalmics Antibiotic Availability And Storage: Each mL of sterile ophthalmic solution contains: tobramycin 0.3%. Nonmedicinal ingredients: benzalkonium chloride (as a preservative), boric acid, purified water, sodium chloride, sodium hydroxide, sodium sulfate, sulfuric acid and tyloxapol. Plastic squeeze bottles of 5 mL with controlled tip applicators. TOBRAMYCIN Rivex Ophthalmics Antibiotic

TOFRANIL® Novartis Pharmaceuticals Imipramine HCl Antidepressant Action and Clinical Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. It possesses anticholinergic properties which are responsible for certain of its side effects. The mechanism of action of imipramine and other tricyclic antidepressants is not well established, but it is thought that it might be related to their…

TOBI™ PathoGenesis Tobramycin (as sulfate) Respiratory Antibiotic Action and Clinical Uses: Pharmacology TOBI is a formulation of tobramycin designed specifically for administration by inhalation. When tobramycin solution for inhalation is inhaled, tobramycin can be detected at high concentration in the sputum of cystic fibrosis patients.: The drug substance, tobramycin, is an aminoglycoside antibiotic derived from S. tenebrarius. Tobramycin, a cationic polar molecule that does not readily cross epithelial membranes, is…

TOBRADEX® Alcon Tobramycin-Dexamethasone Antibiotic-Corticosteroid Action and Clinical Uses: Dexamethasone, a potent corticosteroid, suppresses the inflammatory response to chemical, immunological or mechanical irritants. The bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria. Indications And Clinical Uses: For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exist. Ocular steroids are indicated…

TIMOPTIC®, TIMOPTIC-XE® Merck Frosst Timolol Maleate Elevated Intraocular Pressure Therapy Action and Clinical Timolol is a general beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant or local anesthetic (membrane-stabilizing) activity. Timolol combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biologic response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation…

TIMPILO® Merck Frosst Timolol Maleate-Pilocarpine HCl Elevated Intraocular Pressure Therapy Action and Clinical Uses: Timolol is a nonselective beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Timolol combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biologic response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation…