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TOBRAMYCIN Rivex Ophthalmics Antibiotic Availability And Storage: Each mL of sterile ophthalmic solution contains: tobramycin 0.3%. Nonmedicinal ingredients: benzalkonium chloride (as a preservative), boric acid, purified water, sodium chloride, sodium hydroxide, sodium sulfate, sulfuric acid and tyloxapol. Plastic squeeze bottles of 5 mL with controlled tip applicators. TOBRAMYCIN Rivex Ophthalmics Antibiotic

TOFRANIL® Novartis Pharmaceuticals Imipramine HCl Antidepressant Action and Clinical Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. It possesses anticholinergic properties which are responsible for certain of its side effects. The mechanism of action of imipramine and other tricyclic antidepressants is not well established, but it is thought that it might be related to their…

TOBI™ PathoGenesis Tobramycin (as sulfate) Respiratory Antibiotic Action and Clinical Uses: Pharmacology TOBI is a formulation of tobramycin designed specifically for administration by inhalation. When tobramycin solution for inhalation is inhaled, tobramycin can be detected at high concentration in the sputum of cystic fibrosis patients.: The drug substance, tobramycin, is an aminoglycoside antibiotic derived from S. tenebrarius. Tobramycin, a cationic polar molecule that does not readily cross epithelial membranes, is…

TOBRADEX® Alcon Tobramycin-Dexamethasone Antibiotic-Corticosteroid Action and Clinical Uses: Dexamethasone, a potent corticosteroid, suppresses the inflammatory response to chemical, immunological or mechanical irritants. The bactericidal activity of tobramycin is accomplished by specific inhibition of normal protein synthesis in susceptible bacteria. Indications And Clinical Uses: For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exist. Ocular steroids are indicated…

TIMOPTIC®, TIMOPTIC-XE® Merck Frosst Timolol Maleate Elevated Intraocular Pressure Therapy Action and Clinical Timolol is a general beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant or local anesthetic (membrane-stabilizing) activity. Timolol combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biologic response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation…

TIMPILO® Merck Frosst Timolol Maleate-Pilocarpine HCl Elevated Intraocular Pressure Therapy Action and Clinical Uses: Timolol is a nonselective beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane-stabilizing) activity. Timolol combines reversibly with a part of the cell membrane, the beta-adrenergic receptor, and thus inhibits the usual biologic response that would occur with stimulation of that receptor. This specific competitive antagonism blocks stimulation…

TIMENTIN® SmithKline Beecham Ticarcillin Disodium-Potassium Clavulanate Antibiotic-b-Lactamase Inhibitor Action and Clinical Ticarcillin exerts a bactericidal action against sensitive organisms during the stage of active multiplication through the inhibition of the biosynthesis of bacterial cell wall mucopeptides. Clavulanic acid inhibits specific b-lactamases of some microorganisms and allows ticarcillin to inhibit ticarcillin resistant organisms which produce clavulanic acid sensitive b-lactamases.IndicationsIndications: Indications And Clinical Uses: For the treatment of the following infections when…

TIMOLIDE® Merck Frosst Timolol Maleate-Hydrochlorothiazide Antihypertensive Action and Clinical Uses: Timolide combines the antihypertensive activity of 2 agents: a beta-adrenergic receptor blocking agent (timolol maleate) and a diuretic (hydrochlorothiazide). Timolol is a non-selective beta-adrenergic receptor blocking agent that does not have significant intrinsic sympathomimetic, direct myocardial depressant, or local anesthetic (membrane stabilizing) activity in humans. The mechanism of the antihypertensive effect of beta-adrenergic receptor blocking agents has not yet been…

TIAMOL® Spectropharm Dermatology Fluocinonide Topical Corticosteroid Action and Clinical Uses: Fluocinonide is effective because of the anti-inflammatory, antipruritic and vasoconstrictor actions of fluocinonide.IndicationsIndications: Indications And Clinical Uses: For topical use in the management of acute or chronic dermatoses responsive to corticosteroids. Contra-Indications: Topical corticosteroids are contraindicated in tuberculosis, fungal, most viral lesions of the skin (including herpes simplex, vaccinia and varicella), untreated bacterial infections and also contraindicated in individuals with…

TIAZAC® Crystaal Diltiazem HCI Antihypertensive-Antianginal Action and Clinical Uses: Diltiazem is a calcium ion cellular influx inhibitor (calcium entry blocker or calcium ion antagonist).: Mechanism of Action: The therapeutic effect of this group of drugs is believed to be related to their specific cellular action of selectively inhibiting transmembrane influx of calcium ions into cardiac muscle and vascular smooth muscle. The contractile processes of these tissues are dependent upon the…