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BELLERGAL® SPACETABS® Novartis Pharmaceuticals Belladonna – Ergotamine Tartrate – Phenobarbital Anticholinergic – Antispasmodic – Sedative Indications And Clinical Uses: Functional symptoms such as hot flushes, perspiration, palpitations, dizzy spells, restlessness, apprehension, fatigue, insomnia, headache, for example in patients with anxiety-tension states associated with menopause. Menopausal women who are treated with Bellergal, exhibiting atrophic vaginitis and/or osteoporosis, require specific therapy for these conditions if indicated. Contra-Indications: Narrow-angle glaucoma, sepsis, occlusive vascular…

BECONASE Aq® Glaxo Wellcome Beclomethasone Dipropionate Corticosteroid for Nasal Use Action And Clinical Pharmacology: Beclomethasone dipropionate is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When inhaled intranasally at therapeutic doses, it has a direct anti-inflammatory action within the nasal mucosa, the mechanism of which is not yet completely defined. The minute amount absorbed in therapeutic doses has not been shown to exert any apparent clinical systemic…

BEANO® Block Drug Alpha-D-Galactosidase Alpha Galactosidase Enzyme Action And Clinical Pharmacology: Hydrolysis converts raffinose, stachyose and verbascose into their digestible sugar components: glucose, galactose, sucrose and fructose. Raffinose yields sucrose+ galactose; stachyose yields sucrose+galactose; verbascose yields glucose+fructose+galactose. Indications And Clinical Uses: Helps prevent gas. Beano enzyme has been shown to be effective in both clinical and anecdotal studies with humans when consuming foods with high alpha-linked sugar content. Use results…

BECLOFORTE® Glaxo Wellcome Beclomethasone Dipropionate Corticosteroid for the Treatment of Bronchial Asthma Action And Clinical Pharmacology: Beclomethasone dipropionate is a potent anti-inflammatory steroid with strong topical and weak systemic activity. When inhaled at therapeutic dosages, it has a direct anti-inflammatory action on the bronchial mucosa. Since with therapeutic doses the minute amounts absorbed do not exert any significant systemic effect, inhaled beclomethasone dipropionate can replace oral steroids with the elimination…

BACTROBAN® SmithKline Beecham Mupirocin Topical Antibiotic Action And Clinical Pharmacology: Mupirocin exerts a bactericidal action against sensitive organisms by inhibiting bacterial protein synthesis. It reversibly and specifically binds to bacterial isoleucyl transfer-RNA synthetase Indications And Clinical Uses: For the topical treatment of the following when caused by sensitive strains of staphylococcus and streptococcus species: impetigo, superficially infected dermatoses, lesions which are moist and weeping. For abrasions, minor cuts and wounds,…

BACTRIM™ ROCHE® Roche Trimethoprim – Sulfamethoxazole Antibacterial Action And Clinical Pharmacology: Trimethoprim plus sulfamethoxazole block 2 consecutive steps in the biosynthesis of nucleic acids and proteins essential to many bacteria. Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid. Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by reversibly inhibiting the required enzyme, dihydrofolate reductase. The effect of the dual consecutive action is to reduce…

BARBITURATES Amobarbital Butabarbital Pentobarbital Phenobarbital Secobarbital Anticonvulsant – Sedative-Hypnotic Pharmacology: Barbiturates are nonselective central nervous system (CNS) depressants, capable of producing all degrees of depression from mild sedation and hypnosis to general anaesthesia, deep coma and death. The extent of CNS depression varies with the route of administration, dose and pharmacokinetic characteristics of the particular barbiturate. Patient specific factors such as age, physical or emotional state and the concomitant use…

BARRIERE-HC® Roberts Hydrocortisone – Silicone Dermatitis Therapy Indications And Clinical Uses: Adjunctive treatment of allergic dermatoses and other inflammatory skin conditions amenable to topical corticosteroid therapy (e.g., contact, atopic and seborrheic dermatitis, neurodermatitis, psoriasis and anogenital pruritus). Contra-Indications: Tuberculous and most fungal and viral lesions of the skin, herpes simplex, vaccinia and varicella particularly. Precautions: Although untoward effects associated with the use of topical corticosteroids are uncommon and not to…

BAYCOL® Bayer Cerivastatin Sodium Lipid Metabolism Regulator Action And Clinical Pharmacology: Cerivastatin is an entirely synthetic, enantiomerically pure cholesterol-lowering agent and is structurally similar to the fungal derivatives of this therapeutic class. Cerivastatin is a competitive inhibitor of 3-hydroxy-3methyl-glutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. The inhibition of cholesterol biosynthesis by cerivastatin…

BCG Vaccine (Freeze Dried) Connaught Attenuated Tubercle Bacillus Active Immunizing Agent Action And Clinical Pharmacology: BCG Vaccine (Freeze-Dried) for intracutaneous administration, as prepared by Connaught Laboratories Limited, is made from a culture of an attenuated strain of living bovine tubercle bacillus (Bacillus Calmette-Gurin). It is supplied as a freeze-dried product ready for immediate use following reconstitution with the accompanying diluent, which consists of sterile phosphate-buffered saline. The manufacturing and testing…