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FLEET® PHOSPHO®-SODA Johnson & Johnson• Merck Sodium Phosphates Laxative Action And Clinical Pharmacology: Depending on dosage, sodium phosphates oral solution is useful as a laxative in the relief of constipation, or as a bowel evacuant for a variety of diagnostic, surgical and therapeutic indications. Dibasic sodium phosphate and monobasic sodium phosphate are poorly absorbed from the gastrointestinal tract and retain water in the lumen of the intestine. When administered orally,…

FLEXALL® Chattem Menthol Topical Analgesic Indications And Clinical Uses: For temporary relief from minor arthritis pain, bursitis, tendonitis, backache, strains and sprains. Warnings: For external use only. Keep out of the reach of children. Keep away from eyes, mucous membranes, broken or irritated skin. If rash occurs, discontinue use. Do not bandage tightly or use heating pad. Dosage: Apply generously to muscles and joints and gently massage until gel disappears….

FLAMAZINE® Smith & Nephew Silver Sulfadiazine Topical Antibacterial Action And Clinical Pharmacology: Silver sulfadiazine is released slowly from the cream, and thus rapid depletion of chloride and associated electrolyte disturbances are minimized. Silver sulfadiazine is not inhibited by PABA. In burned pigs, the absorption of silver was less than 1% of the applied dose, however 5 to 8% of the sulfadiazine was absorbed. There is very little penetration of the…

FLAMAZINE® C Smith & Nephew Silver Sulfadiazine – Chlorhexidine Digluconate Topical Antibacterial Action And Clinical Pharmacology: The mechanism of silver sulfadiazine’s antibacterial action has not been fully elucidated. After exposure to the drug, structural changes in the bacterial cell membrane occur, including distortion and enlargement of the cell and a weakening of the cell wall membrane. This is accompanied by reduced viability in sensitive strains. The silver sulfadiazine molecule dissociates…

FLAREX® Alcon Fluorometholone Acetate Corticosteroid Action And Clinical Pharmacology: Adrenocorticoids suppress the inflammatory response (edema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, deposition of collagen and scar formation) to chemical, immunological or mechanical irritants. Adrenocorticoids may cause a rise in intraocular pressure in susceptible individuals. They are absorbed into aqueous humor, cornea, iris, choroid, ciliary body, and retina. Systemic absorption occurs but may be significant only at higher doses…

FLAXEDIL® Rh´ne-Poulenc Rorer Gallamine Triethiodide Muscle Relaxant Action And Clinical Pharmacology: Gallamine is a competitive neuromuscular blocking agent. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release. Following usual i.v. doses muscle relaxation occurs rapidly and reaches a…

FIORINAL® Novartis Pharmaceuticals ASA – Caffeine – Butalbital Analgesic – Sedative Indications And Clinical Uses: For tension (or muscle contraction) headache and conditions where a simultaneous sedative and analgesic action is required, such as mixed migraine headaches, menstrual and postpartum tension and pain. Contraindications, Precautions and Adverse Effects: See Fiorinal-C monograph. A possible association between Reye’s syndrome and the use of salicylates has been suggested but not established. Reye’s syndrome…

FIORINAL®-C 1/4, 1/2 Novartis Pharmaceuticals ASA – Caffeine – Codeine – Butalbital Analgesic – Sedative Indications And Clinical Uses: The relief of acute and chronic pain of mild, moderate, or severe degree, which is accompanied by tension or anxiety and in all indications where a simultaneous sedative and analgesic action is required, such as: tension headache, musculoskeletal pain, including low back pain, postoperative, post partum pain, dysmenorrhea, pain associated with…

FLAGYL® Rh´ne-Poulenc Rorer Metronidazole Antibacterial – Antiprotozoal Action And Clinical Pharmacology: Metronidazole is bactericidal against anaerobic bacteria, it exerts trichomonacidal activity and is also active against Giardia lamblia and Entamoeba histolytica. Its exact mechanism of action has not been entirely determined as yet. It has been proposed that an intermediate in the reduction of metronidazole, produced only in anaerobic bacteria and protozoa is bound to deoxyribonucleic acid and electron-transport proteins,…

FLAGYSTATIN® R´ne-Poulenc Rorer Metronidazole – Nystatin Trichomonacide – Moniliacide Indications And Clinical Uses: Mixed vaginal infection due to Trichomonas vaginalis and C. albicans. Contra-Indications: Hypersensitivity to either of the components. Combined treatment with oral Flagyl should be avoided in cases of active neurological disorders or a history of blood dyscrasia, hypothyroidism or hypoadrenalism unless in the opinion of the physician the benefits outweigh the possible hazard to the patient. See…